There are many lopsided matchups on the NFL betting board in Week 13, including a clash between the New York Giants and Seattle Seahawks on Sunday evening.
The 8-3 Seahawks are fresh off a win on Monday Night Football and opened as 10-point favorites against a Giants team that has won three games in a row.
We break down the NFL odds with our best picks and predictions for the Giants vs Seahawks on Sunday, December 6, with kickoff at 4:05 p.m. ET.
New York Giants at Seattle Seahawks Betting Preview
It's expected to be a mild afternoon at Lumen Field in Seattle, with temperatures around 49 degrees, breezes reaching up to nine miles per hour, and a six percent chance of rain. Be sure to monitor the gametime conditions with our NFL weather info.
Giants: Daniel Jones QB (Out), Devonta Freeman RB (Out), Sam Beal CB (Out), Dante Pettis WR (Out), Nate Solder T (Out).
Seahawks: Brandon Shell T (Out), Travis Homer (Out), Greg Olsen TE (Out), Quinton Dunbar CB (Out), Lano Hill S (Out), Bruce Irvin LB (Out), Josh Gordon WR (Out).
Find our latest NFL injury reports.
Betting Trend to Know
The Under is 5-1 in the Giants' last six games overall. Find more NFL betting trends for Giants vs. Seahawks.
Against the Spread (ATS) Pick
Recent reports suggest that Jones avoided a serious leg injury on the weekend and could suit up in Week 13. That could give a betting advantage to the Giants who are 4-1 ATS in their last five games and have outplayed expectations on the road recently, going 21-8 ATS in their previous 29 away contests.
Led by Russell Wilson and a high-flying offense, the Seahawks are 8-3 SU this season. However, a leaky defense has made it difficult for Seattle to cover the spread, causing them to go just 2-5 ATS in their last seven games.
The Giants defense isn't outstanding but it has been solid, ranking ninth in the league in scoring defense (23 points per game) and 10th in total defense (340.1 yards per game). Sure, they've faced off against some pretty pathetic offenses in the NFC East but they also limited the Buccaneers to 364 yards and the Rams to 240 earlier this year.
Are they going to shut down Wilson and the passing game? Probably not, but they should be able to keep this game close enough to cover.
PREDICTION: New York Giants +10 (-110)
With an explosive offense and a lax defense, Seattle was a profitable Over play for the first half of the year, but has now cashed the Under in three consecutive contests.
The Seahawks also tend to play lower-scoring games against poor opponents, going 4-0 to the Under in their last four games against teams with a losing record.
Regardless of who plays QB, the Giants have no real weapons surrounding them, with plodding running back Wayne Gallman the best in the backfield and second-year wideout Darius Slayton leading the team with just 53 receiving yards per game.
New York ranks 30th in the league in scoring with 19.5 ppg and is 5-1 to the Under in the last six contests. Take the Under again.
PREDICTION: Under 48 (-110)
Seahawks wide receiver D.K. Metcalf leads the NFL in receiving yards this season and is coming off a 177-yard performance on Monday night against the Eagles.
Not only does Metcalf average 94.5 receiving yards per game he's been very consistent hitting the 90-yard plateau in eight of his 11 games this season.
Despite a strong campaign for new Giants cornerback James Bradberry, the G-Men are merely average at defending against wideouts, ranking 16th in the league in yards allowed to opposing WRs. Take the Over on Metcalf's receiving yard total of 78.5.
PREDICTION: D.K. Metcalf Over 78.5 receiving yards (-120)
Giants vs Seahawks Betting Card
- New York Giants +10 (-110)
- Under 48 (-110)
- D.K. Metcalf Over 78.5 receiving yards (-120)
Did you know that if you parlayed this week’s NFL Giants vs. Seahawks picks, you could win $56.82 on a $10 bet?
Use our NFL parlay calculator to create your own parlays and see their potential payouts.
Where Can I Bet on the NFL?
You can bet on NFL odds at every online and casino sportsbooks, including NFL moneylines, spreads, Over/Under totals and a ton of NFL prop odds. Head over to our best-suggested sportsbooks for the top spots to bet on NFL odds in your area.