NFL Week 4 odds launch on Thursday Night Football as the Cleveland Browns play host to the division-rival Pittsburgh Steelers. Meanwhile, Sunday’s main slate features a heavyweight NFC showdown between the Los Angeles Rams and Philadelphia Eagles.
To cap off Week 4, Monday Night Football serves up an NFC South rivalry battle as the Atlanta Falcons head into the Caesars Superdome to take on the New Orleans Saints.
As lines take action, we're tracking the latest NFL odds, spreads, moneylines, and totals for every game on the slate.
NFL odds Week 4
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
 Steelersvs  Browns |
-2.5 71% +2.5 29% |
58% 44% |
o37.5 51% u37.5 54% |
 Coltsvs  Commanders |
-4.5 49% +4.5 51% |
66% 35% |
o46.5 52% u46.5 54% |
 Patriotsvs  Bills |
+5.5 19% -5.5 81% |
31% 71% |
o50.5 51% o50.5 54% |
 Jetsvs  Bears |
+3 49% -3 51% |
39% 66% |
o43.5 52% u43.5 54% |
 Jaguarsvs  Bengals |
+2.5 36% -2.5 64% |
45% 59% |
o50.5 53% u50.5 52% |
 Cardinalsvs  Giants |
+2.5 47% -2.5 53% |
47% 58% |
o43.5 58% u43.5 42% |
 Ramsvs  Eagles |
-2.5 41% +2.5 59% |
59% 44% |
o46.5 51% u46.5 54% |
 Packersvs  Buccaneers |
-1.5 48% +1.5 52% |
51% 50% |
o45.5 54% u45.5 51% |
 Titansvs  Ravens |
+10.5 29% -10.5 71% |
16% 86% |
o44.5 54% u44.5 51% |
 Cowboysvs  Texans |
+2.5 33% -2.5 67% |
42% 59% |
o47.5 52% u47.5 53% |
 Dolphinsvs  Vikings |
+10.5 30% -10.5 70% |
17% 85% |
o43.5 52% u43.5 55% |
 Chiefsvs  Raiders |
-5.5 65% +5.5 35% |
69% 32% |
o45.5 54% u45.4 52% |
 Broncosvs  49ers |
+3.5 28% -3.5 72% |
35% 66% |
o46.5 51% u46.5 52% |
 Chargersvs  Seahawks |
+6.5 28% -6.5 72% |
27% 75% |
o43.5 52% u43.5 51% |
 Lionsvs  Panthers |
-2.5 62% +2.5 38% |
59% 46% |
o49.5 52% u49.5 52% |
 Falconsvs  Saints |
+3.5 25% -3.5 75% |
38% 67% |
o45.5 56% u45.5 44% |
Lines as of 9-23.
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Thursday Night Football: Steelers vs Browns odds (8:15 p.m. ET, Prime Video)
Opening line
- Cleveland +2.5
- Over/Under 37.5
- View full Pittsburgh vs. Cleveland odds and matchup
- Read our Pittsburgh vs. Cleveland picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Thursday Night Football odds
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Sunday Night Football: Lions vs Panthers odds (8:20 p.m. ET, NBC)
Opening line
- Carolina +2.5
- Over/Under 49.5
- View full Detroit vs. Carolina odds and matchup
- Read our Detroit vs. Carolina picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Sunday Night Football odds
Monday Night Football: Falcons vs Saints odds (8:15 p.m., ESPN)
Opening line
- New Orleans -3.5
- Over/Under 45.5
- View full Atlanta vs. New Orleans odds and matchup
- Read our Atlanta vs. New Orleans picks and predictions (coming soon)
Opening line analysis coming soon!
Also see: full Monday Night Football odds
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Odds are correct at the time of publishing and are subject to change.
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