The Auburn Tigers put their 69-game non-conference home winning streak on the line against No. 12 Arizona Wildcats on Friday, November 13, at 9 p.m. ET inside Neville Arena.
My Arizona vs. Auburn prediction targets the Wildcats as 2.5-point road favorites, with a potential shootout and a three-leg combo worth exploring.
For more expert analysis and daily plays, check out the latest college basketball picks.
TOP PICK
Who will win Arizona vs Auburn: Arizona -2.5
I'm following the line movement and taking the Arizona Wildcats -2.5, up to -4.5. Arizona opened as 1.5-point favorites and has been steamed up to the current number, even though KenPom predicts the Auburn Tigers will win by two points.
Arizona is 44-28-3 against the spread (ATS) in non-conference games since head coach Tommy Lloyd took over in 2021. Lloyd has taken the Wildcats to four Sweet 16s, including last season's Final Four. Plus, Arizona is 37-17 straight-up in true road games in the Lloyd era.
I'm expecting Auburn's program to regress the further we move away from the Bruce Pearl era. Bruce's son, Steven, succeeded him last season, and it was the first time the Tigers didn't make the NCAA Tournament since 2021.

Arizona vs Auburn Over/Under pick: Over 158.5
The Over 158.5 is tradable up to 160.5.
Arizona is 25-12 to the Over as a road favorite, with totals clearing by an average of 5.4 points during Lloyd's tenure. The Wildcats have consistently played fast under Lloyd, ranking 49th in adjusted tempo, according to KenPom.
Arizona should have the upper hand in controlling possessions, with better turnover rates on both ends of the floor. There's also a recent blueprint for this matchup: The Wildcats hammered Auburn 97-68 last season, pushing the game Over 161.5 while playing at a faster pace than Auburn's season average.
Arizona vs Auburn combo
For the record, I'm only risking a quarter-unit on college hoops combos. Adding Auburn's team total Under 77.5 boosts the payout to 8.33x, compared to 3.74x with Arizona's team total Over.
And here's why I'm comfortable taking the bigger payout: Arizona and Auburn cleared the full-game total last season even though the Tigers scored just 68 points. Auburn has also stayed Under its team total in seven of its last 11 games dating back to last season. I can see Arizona doing most of the heavy lifting offensively while keeping Auburn below 78.
Arizona vs Auburn combo
- Wildcats -2.5
- Over 158.5
- Tigers team total Under 77.5
- Top picks: 5-1, +3.42 units
- Combos: 3-3, +1.83 units
- Props: 3-1, +1.65 units
Arizona vs Auburn odds
For help understanding probabilities, see our odds calculator.
- Spread: Arizona -2.5 | Auburn +2.5
- Over/Under: Over 158.5 | Under 158.5
- Moneyline: Arizona 57% | Auburn 44%
Check the latest college basketball odds for more on tonight's Arizona vs. Auburn matchup.
Arizona vs Auburn trend
The Tigers went 8-14 ATS as an underdog last season with a -3.5 spread differential. Find more college basketball betting trends.
How to watch Arizona vs Auburn
| Location | Neville Arena, Auburn, Ala. |
| Date | Friday, Nov. 13, 2026 |
| Tip off | 9 p.m. ET |
| TV | ESPN2 |
Arizona vs Auburn latest injuries
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