The New York Knicks will try to break out of their four-game slide tonight as they host the Brooklyn Nets at Madison Square Garden.
New York may well finally get a win tonight, but my Nets vs. Knicks predictions still like Brooklyn to cover the spread.
Keep reading to see the full analysis of tonight’s matchup in my free NBA picks for Wednesday, January 21.
Nets vs Knicks prediction
Nets vs Knicks best bet: Nets +11.5 (-110)
The New York Knicks are currently in freefall, having lost four straight and nine of their last 11. Despite comments made earlier this month by owner James Dolan, this has looked more like a team that has to fight to stay out of the play-in tournament than one that’s on its way to the NBA Finals.
Coming off an embarrassing loss to the Dallas Mavericks in which they trailed by as many as 30 points, the Knicks have one of their best chances to snap out of their funk against the 12-29 Nets. New York has beaten the Brooklyn Nets in each of their last 12 meetings, and the Nets have lost seven of their last eight.
But even if the Knicks can manage to get back in the win column tonight, covering a large spread may be another story.
New York hasn’t covered as a double-digit favorite since December 5, and the Knicks have managed to lose outright in their last two games as a 10+ point favorite.
It’s hard to blow teams out when you’re playing as poorly on the defensive end as the Knicks, who are giving up 114.9 ppg on the year. With this many points on the board, I’m taking the Nets to cover.

Nets vs Knicks same-game parlay
The Knicks have also been struggling on the offensive end, scoring 101 points or less in three of their last four games. Combined with Brooklyn’s own offensive struggles, the Under looks like a good play tonight.
Still, I’ll take center Nic Claxton to hit his personal Over at 10.5 points, as he is averaging 12.8 ppg and has hit this total in each of his last two games.
Nets vs Knicks SGP
- Nets +11.5
- Under 220.5
- Nic Claxton Over 10.5 points
Our "from downtown" SGP: Eager about Egor
The Knicks are allowing opponents to shoot 37.5% from 3-point range, and Egor Demin has hit at least three shots from deep in five of his last seven games.
Nets vs Knicks SGP
- Nets +11.5
- Under 220.5
- Nic Claxton Over 10.5 points
- Egor Demin Over 2.5 threes
Nets vs Knicks odds
- Spread: Nets +11.5 | Knicks -11.5
- Moneyline: Nets +460 | Knicks -620
- Over/Under: Over 220.5 | Under 220.5
Nets vs Knicks betting trend to know
The Knicks are 2-11 ATS in their last 13 games overall. Find more NBA betting trends for Nets vs. Knicks.
How to watch Nets vs Knicks
| Location | Madison Square Garden, New York, NY |
| Date | Wednesday, January 21, 2026 |
| Tip-off | 7:30 p.m. ET |
| TV | YES, MSG |
Nets vs Knicks latest injuries
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