The New York Yankees are -110 favorites on the road against the Detroit Tigers tonight at Comerica Park, with the total set at 7.5 for the middle game of a three-game series.
New York limps in having dropped three straight and four of its last five, while Detroit rides a four-game winning streak.
My Yankees vs Tigers predictions and MLB picks for Tuesday, June 23, expect those trends to continue.
Who will win Yankees vs Tigers today: Tigers (-104)
I've faded Carlos Rodon a good deal this season, and I'm doing it again, backing the Detroit Tigers. He has elite strikeout stuff, but there's a notable issue in this matchup.
His Bottom 9th percentile walk rate at just over 13% puts free runners on against a Tigers offense that has heated up as of late and does a good job of putting the ball into play.
Casey Mize has historically handled this group with a 3.63 ERA across four career starts, including two quality starts against the New York Yankees last season.
That makes sense, too, given his swing-and-miss stuff that has peaked this season with a 25%+ strikeout rate. I'd play this to -120.

Yankees vs Tigers Over/Under pick: Over 7.5 (-116)
Both starters carry command issues, and both lineups are built to exploit them.
Mize returned from his second IL stint of the season last Wednesday and admitted his last outing was undone by too many three-ball counts — allowing three runs in just over four innings against a similar-hitting-profile team in the Houston Astros.
The Yankees lineup still has Paul Goldschmidt turning time back with a .898 OPS and Ben Rice (.389 xwOBA) doing damage. While I think Mize has some success, he'll give up enough here with the Tigers doing the heavy lifting. Play to 8.
- ML/RL bets: 30-26, +6.67 units
- Over/Under bets: 35-22, +16.82 units
Yankees vs Tigers weather
Temps are expected to hover around 70 degrees F come game time, with little chance of rain and slight winds.
Yankees vs Tigers odds
- Moneyline: Yankees -115 | Tigers +100
- Run line: Yankees -1.5 | Tigers +1.5
- Over/Under: Over 7.5 | Under 7.5
Yankees vs Tigers trend
The Detroit Tigers have hit the moneyline in 12 of their last 18 games (+5.65 Units / 26% ROI). Find more MLB betting trends for Yankees vs. Tigers.
How to watch Yankees vs Tigers and game info
| Location | Comerica Park, Detroit, MI |
| Date | Tuesday, June 23, 2026 |
| First pitch | 6:40 p.m. ET |
| TV | YES, DSN |
| Yankees starting pitcher | Carlos Rodon (3-2, 3.50 ERA) |
| Tigers starting pitcher | Casey Mize (2-4, 2.58 ERA) |
Yankees vs Tigers latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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