The New York Yankees and Boston Red Sox will renew a rivalry with a weekend series in the Bronx starting this evening.
The Yankees swept Boston earlier this year already and will look to extend their winning streak over their fierce foe to six tonight. The Bronx Bombers are favorites tonight, and we expect them to show why against a Red Sox arm that’s due for regression.
Read all about it in my Yankees vs. Red Sox predictions and MLB picks for Friday, June 5.
Who will win Red Sox vs Yankees today: Yankees moneyline (-140)
Despite their struggles in the wake of AL MVP Aaron Judge's injury, the New York Yankees should take care of business tonight, and I'd play this to -165.
Sonny Gray is due for negative regression. His 4.39 expected ERA is nearly a full run and a half higher than his actual ERA. Pulling these metrics down the most is a barrel rate that sits in the Bottom 33% of the sport.
Judge's absence is felt, but the Yankees still rank first in baseball in both barrel and hard-hit rate, built to expose Gray's contact profile.
COVERS INTEL: Sonny Gray drops his four-seam usage to 9% against right-handed hitters, forcing him into a cutter-heavy mix against a Yankees lineup that leads the league in barrel rate.
Red Sox vs Yankees Over/Under pick: Over 7.5 (-120)
This is a two-unit play on the Over, my seventh of the season. I made this number 8.3 and would play it to 8.
We've talked about Gray and why this Yankees lineup can cause him problems, even without Judge. The other side is the Boston Red Sox offense, and I feel good about them in this matchup.
Ryan Weathers' nearly 30% strikeout rate is impressive, but a Bottom-15 percentile barrel rate cannot be trusted with a total this low, especially against a Boston lineup with four starters in the Top 30% of those metrics.
- ML/RL bets: 27-21, +5.94 units
- Over/Under bets: 30-18, +14.07 units
Red Sox vs Yankees odds
- Moneyline: Red Sox +125 | Yankees -150
- Run line: Red Sox +1.5 (-170) | Yankees -1.5 (+145)
- Over/Under: Over 8 | Under 8
Red Sox vs Yankees trend
The Yankees have cashed the Over in six of their last eight games for +3.75 units and a 43% ROI. Find more MLB betting trends for Red Sox vs. Yankees.
How to watch Red Sox vs Yankees and game info
| Location | Yankee Stadium, Bronx, NY |
| Date | Friday, June 5, 2026 |
| First pitch | 7:05 p.m. ET |
| TV | Peacock |
| Red Sox starting pitcher | Sonny Gray (6-1, 3.06 ERA) |
| Yankees starting pitcher | Ryan Weathers (2-3, 3.52 ERA) |
Red Sox vs Yankees latest injuries
Red Sox vs Yankees weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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