The Chicago Cubs and Los Angeles Dodgers both feature Top-5 offenses, which were on full display in a 10 run series opener.
My Cubs vs. Dodgers predictions see another high-scoring affair in the cards Saturday night.
Let’s take a closer look at my daily MLB picks for April 25.
Who will win Cubs vs Dodgers today: Dodgers (-140)
Colin Rea has pitched very well for the Chicago Cubs but his two best starts came against an 8-18 Philadelphia Phillies team.
There are also a couple of concerns in his numbers. For one, he ranks 26th among today’s projected starters in soft contact rate. He’s not generating much.
That’s not a great recipe heading into a matchup with the Los Angeles Dodgers, who rank first in hard hit rate against righties this season.
He also ranks 40th percentile or worst in whiffs and K%. He doesn’t miss many bats, and that could lead to problems against a powerful Dodgers offense.

Cubs vs Dodgers Over/Under pick: Over 9.5 (+100)
The Dodgers rank first in average, second in OBP, and fourth in runs per game. They also hit the ball as hard as anybody, and Rea has not induced a lot of soft contact.
Chicago should score plenty of runs as well. They have plated at least six runs in six consecutive road games, and 4+ in eight of 10 away dates this season.
Dodgers starter Roki Sasaki is sporting a 6.11 ERA and allowing more than two homers per nine innings, which doesn’t set up well facing a Cubs team that slots fifth in homers.
- ML/RL bets: 5-3, +1.18 units
- Over/Under bets: 2-6, -4.72 units
Cubs vs Dodgers odds
- Moneyline: Chicago (+130) | Los Angeles (-150)
- Run line: Chicago +1.5 (-145) | Los Angeles -1.5 (+125)
- Over/Under: Over 9.5 (+100) | Under 9.5 (-120)
Cubs vs Dodgers trend
The Los Angeles Dodgers have hit the Moneyline in 35 of their last 50 games (+6.45 Units / 7% ROI). Find more MLB betting trends for Cubs vs. Dodgers.
How to watch Cubs vs Dodgers and game info
| Location | Dodger Stadium, Los Angeles, CA |
| Date | Saturday, April 25, 2026 |
| First pitch | 7:15 p.m. ET |
| TV | FOX |
| Cubs starting pitcher | Colin Rea (3-0, 3.00 ERA) |
| Dodgers starting pitcher | Roki Sasaki (0-2, 6.11 ERA) |
Cubs vs Dodgers latest injuries
Cubs vs Dodgers weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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