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MLB Picks

Get free expert and computer MLB picks for every game on Sept. 23, 2026.

New Computer Picks powered by Odds Shark

Predicted Score

HOU logo
HOU
HOU

3.89 @ 4.34

SEA
SEA logo
SEA

Astros vs Mariners · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

HOU logo
HOU
HOU

3.89

+120

o7.0 -120

+3.5 -700

SEA logo
SEA
SEA

4.34

-130

u7.5 -125

-3.5 +400

LA Angels @ Athletics
Matchup Stats

Predicted Score

LAA logo
LAA
LAA

5.42 @ 5.15

ATH
ATH logo
ATH

Angels vs Athletics · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

LAA logo
LAA
LAA

5.42

-107

o9.5 -104

-1.5 +152

ATH logo
ATH
ATH

5.15

+100

u9.5 -109

+1.5 -162

Top Projection Mike Trout o0.5 Total RBIs (+155)
o0.5+155
Minnesota @ San Francisco
Matchup Stats

Predicted Score

MIN logo
MIN
MIN

4.40 @ 3.39

SF
SF logo
SF

Twins vs Giants · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

MIN logo
MIN
MIN

4.40

-130

o7.0 -115

-1.5 +135

SF logo
SF
SF

3.39

+117

u7.5 -120

+1.5 -152

Top Projection Luke Keaschall o0.5 Total RBIs (+265)
o0.5+265
San Diego @ LA Dodgers
Matchup Stats

Predicted Score

SD logo
SD
SD

4.63 @ 5.17

LAD
LAD logo
LAD

Padres vs Dodgers · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

SD logo
SD
SD

4.63

+112

o8.5 +101

+1.5 -185

LAD logo
LAD
LAD

5.17

-125

u8.5 -112

-1.5 +165

Washington @ Detroit
Matchup Stats

Predicted Score

WAS logo
WAS
WAS

3.59 @ 3.75

DET
DET logo
DET

Nationals vs Tigers · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

WAS logo
WAS
WAS

3.59

+160

o7.5 -118

+1.5 -140

DET logo
DET
DET

3.75

-180

u8.5 -142

-1.5 +122

Toronto @ Baltimore
Matchup Stats

Predicted Score

TOR logo
TOR
TOR

4.13 @ 4.33

BAL
BAL logo
BAL

Blue Jays vs Orioles · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TOR logo
TOR
TOR

4.13

+105

o7.5 +105

+1.5 -225

BAL logo
BAL
BAL

4.33

-120

u7.5 -125

-1.5 +175

Minnesota @ San Francisco
Matchup Stats
Milwaukee @ Philadelphia
Matchup Stats

Predicted Score

MIL logo
MIL
MIL

4.10 @ 3.98

PHI
PHI logo
PHI

Brewers vs Phillies · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

MIL logo
MIL
MIL

4.10

-136

o7.5 -102

-1.5 +135

PHI logo
PHI
PHI

3.98

+120

u7.5 -113

+1.5 -150

St. Louis @ Pittsburgh
Matchup Stats

Predicted Score

STL logo
STL
STL

4.30 @ 4.17

PIT
PIT logo
PIT

Cardinals vs Pirates · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

STL logo
STL
STL

4.30

--

--

--

PIT logo
PIT
PIT

4.17

--

--

--

Tampa Bay @ NY Yankees
Matchup Stats

Predicted Score

TB logo
TB
TB

3.76 @ 4.14

NYY
NYY logo
NYY

Rays vs Yankees · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

TB logo
TB
TB

3.76

+120

o7.0 -105

+1.5 -180

NYY logo
NYY
NYY

4.14

-139

u7.5 -136

-1.5 +161

Cleveland @ Boston
Matchup Stats

Predicted Score

CLE logo
CLE
CLE

3.81 @ 3.78

BOS
BOS logo
BOS

Guardians vs Red Sox · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CLE logo
CLE
CLE

3.81

+120

o7.0 -118

+1.5 -186

BOS logo
BOS
BOS

3.78

-130

u7.5 -120

-1.5 +169

Cincinnati @ Atlanta
Matchup Stats

Predicted Score

CIN logo
CIN
CIN

3.86 @ 4.85

ATL
ATL logo
ATL

Reds vs Braves · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CIN logo
CIN
CIN

3.86

+210

o7.0 -125

+1.5 -105

ATL logo
ATL
ATL

4.85

-235

u7.5 -120

-1.5 -110

Chi. White Sox @ Kansas City
Matchup Stats

Predicted Score

CHW logo
CHW
CHW

4.79 @ 4.89

KC
KC logo
KC

White Sox vs Royals · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

CHW logo
CHW
CHW

4.79

-112

o8.5 -107

-1.5 +150

KC logo
KC
KC

4.89

-102

u8.5 +100

+1.5 -173

Miami @ Chi. Cubs
Matchup Stats

Predicted Score

MIA logo
MIA
MIA

3.79 @ 4.63

CHC
CHC logo
CHC

Marlins vs Cubs · Prediction & Game Odds

Team

Predicted Score

ML

Total

Run Line

MIA logo
MIA
MIA

3.79

+150

o6.5 -137

+1.5 -150

CHC logo
CHC
CHC

4.63

-170

u7.5 -145

-1.5 +135

Houston Astros image thumbnail HOU @ Seattle Mariners image thumbnail SEA Tue, Sep 22 • 9:40 PM ET
Total Home Runs
Yordan Alvarez logo Yordan Alvarez o0.5 Total Home Runs (+257)
Best Odds
Pick made: 7 hours ago
Colby Marchio logo
Colby Marchio
Contributor

We can finally trust the big fella once again, as Yordan Alvarez draws Seattle Mariners right-hander Logan Gilbert. The Houston Astros slugger owns a .559 SLG, .265 ISO, 57%+ hard-hit rate and 14.3% barrel rate over his last 10 games. Alvarez also enters Tuesday with an elite rating on Batters-Box and covers 100% of Gilbert’s pitch mix. Among 63 elite ratings this season, Alvarez has gone yard 22.22% of the time. Meanwhile, Gilbert’s last 30 left-handed hitters have posted a 52%+ hard-hit rate, 10.5% barrel rate, .460 xBA and .669 xSLG. Take this up to 30%.

Total Home Runs
Cal Raleigh logo Cal Raleigh o0.5 Total Home Runs (+300)
Best Odds
Pick made: 10 hours ago
Todd Cordell logo
Todd Cordell
Betting Analyst

Cal Raleigh is back and better than ever. Okay, maybe not ever – but he’s back!

Raleigh has hammered the fastball-sweeper combination over the last 25 games, posting a ridiculous .478 ISO and 35.7% barrel rate.

Raleigh only has seven career at-bats against Cristian Javier but hit safely in three of them, with one leaving the park.

View 14 Picks
Los Angeles Angels image thumbnail LAA @ Athletics Athletics image thumbnail ATH Tue, Sep 22 • 9:40 PM ET
Total Bases
Henry Bolte logo
Henry Bolte o1.5 Total Bases (+120)
Projection 1.8
Best Odds
Pick made: 15 minutes ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Henry Bolte as the best batter in MLB when estimating his BABIP skill.. Henry Bolte is projected to hit 1st in the batting order in today's game, which would be an upgrade from his 51% rate of hitting in the bottom-half of the batting order this season.. Sutter Health Park profiles as the #1 ballpark in the majors for righty home runs, per the leading projection system (THE BAT).. In the league, Sutter Health Park has the 4th-lowest average fence height.. Hot weather is strongly correlated with more offense (and fewer strikeouts), and the weather report forecasts the hottest weather on the slate today at 83°.
Total Bases
Jonah Heim logo
Jonah Heim o1.5 Total Bases (+140)
Projection 1.67
Best Odds
Pick made: 15 minutes ago
EV Model Rating
Star rating: 3 out of 5
Sutter Health Park profiles as the #1 ballpark in the majors for righty home runs, per the leading projection system (THE BAT).. In the league, Sutter Health Park has the 4th-lowest average fence height.. Hot weather is strongly correlated with more offense (and fewer strikeouts), and the weather report forecasts the hottest weather on the slate today at 83°.. As a switch-hitter who is best from the 0 side of the dish, Jonah Heim will have the advantage of batting from from his better side against Yusei Kikuchi in this game.. The Los Angeles Angels infield defense projects as the 4th-worst out of all the teams in action today.
View 10 Picks
Minnesota Twins image thumbnail MIN @ San Francisco Giants image thumbnail SF Tue, Sep 22 • 9:45 PM ET
Total Home Runs
Drew Gilbert logo Drew Gilbert o0.5 Total Home Runs (+770)
Best Odds
Pick made: 10 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Play up to 20%. Drew Gilbert's recent power profile makes him an intriguing longshot. He's homered twice in five games while producing a .500 ISO, 60% hard-hit rate, and 20% barrel rate lately. Bradley has also been more vulnerable to home runs on the road, giving Gilbert a legitimate path to another bomb.

Total
Minnesota Twins image thumbnail San Francisco Giants image thumbnail o7.5 (-101)
Best Odds
Pick made: 10 hours ago
Quinn Allen logo
Quinn Allen
Betting Analyst

Play up to 55%. The bullpen matchup creates plenty of late scoring potential. San Francisco's relief corps has posted a 6.73 FIP with 2.45 HR/9 allowed over the last week, while Minnesota's pen hasn't exactly been dominant either. At only 7.5, one rough relief inning could quickly push this Over.

View 13 Picks
San Diego Padres image thumbnail SD @ Los Angeles Dodgers image thumbnail LAD Tue, Sep 22 • 10:10 PM ET
Total Home Runs
Jackson Merrill logo Jackson Merrill o0.5 Total Home Runs (+465)
Best Odds
Pick made: 7 hours ago
Colby Marchio logo
Colby Marchio
Contributor

San Diego Padres young buck Jackson Merrill is my favorite home run look in this matchup against Los Angeles Dodgers right-hander Roki Sasaki. Sasaki has gone back to his struggling ways, with the last 60 lefties he has faced owning a .417 xBA, .524 xSLG and .363 xwOBA. Meanwhile, Merrill has been crushing the ball over his last 10 games, maintaining a 67.7% hard-hit rate with a .628 SLG and .233 ISO. Sasaki has also posted a 5.02 ERA and 5.48 xERA over his last three starts while allowing nearly 46% hard contact. I’m backing Merrill to go yard.

Total Home Runs
Fernando Tatis Jr. logo Fernando Tatis Jr. o0.5 Total Home Runs (+373)
Best Odds
Pick made: 13 hours ago
JD Yonke logo
JD Yonke
Betting Analyst

Fernando Tatis Jr. has been scoring hot at the dish, leaving the yard five times in his last nine games. Dodger Stadium's 124 Park Factor for home runs means that there's an increased chance of Tatis continuing his fine form by popping a long ball.

 

View 15 Picks
Toronto Blue Jays image thumbnail TOR @ Baltimore Orioles image thumbnail BAL Wed, Sep 23 • 1:35 PM ET
Total Home Runs
George Springer logo George Springer o0.5 Total Home Runs (+850)
Pick made: 10 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

What's wrong with a little double-dip on Springer tonight? Not only does he have strong numbers against Bassitt (2 HR, .631 xSLG), but six of his 15 homers this year have come off breaking balls - and we all know the veteran righty loves to throw the kitchen sink at hitters. If someone is going yard tonight, Springer is the most likely candidate, and at +850, we can't turn down that price.

Total
Toronto Blue Jays image thumbnail Baltimore Orioles image thumbnail o7.5 (+100)
Best Odds
Pick made: 10 hours ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

I'd price this closer to -110, so we're going to take advantage of this value. The Blue Jays see a familiar face on the bump in Chris Bassitt tonight, and while he's been fine over his last two starts, his 4.96 xERA suggests Toronto should be able to get to him. I'm expecting the Blue Jays to manufacture runs, with Bassitt posting a career-high xBA (.279) and career-low K rate (16.4%) this season. On the other side is Max Scherzer, who Baltimore just tagged for six earned runs 11 days ago. No matter how you slice it, tonight looks like we'll see some offensive fireworks. 

View 4 Picks
Milwaukee Brewers image thumbnail MIL @ Philadelphia Phillies image thumbnail PHI Wed, Sep 23 • 6:40 PM ET
Moneyline
Milwaukee Brewers image thumbnail MIL (-136)
Best Odds
Pick made: 2 minutes ago
Chris Vasile logo
Chris Vasile
Publishing Editor

Milwaukee has won eight of its last 10, and I like the pitching advantage with Logan Henderson. The right-hander owns a 2.51 ERA and 0.81 WHIP and has allowed just eight earned runs over his last five starts. Philadelphia counters with Aaron Nola and a bullpen carrying a 4.34 ERA. With the Brewers owning MLB's best record and getting the better starter and relief corps, -136 is a price I'm willing to lay.

View Pick
Cleveland Guardians image thumbnail CLE @ Boston Red Sox image thumbnail BOS Wed, Sep 23 • 7:10 PM ET
Total
Cleveland Guardians image thumbnail Boston Red Sox image thumbnail u7.5 (-120)
Best Odds
Pick made: a minute ago
Chris Vasile logo
Chris Vasile
Publishing Editor

Sonny Gray has been excellent down the stretch, posting a 2.61 ERA over his last five starts while averaging six innings per outing. Four of those five games finished with seven runs or fewer. Foster Griffin has a 3.06 ERA of his own and held Boston to one run over five innings earlier this season. With two starters capable of working deep, I'm backing Under 7.5.

View Pick

What Is An MLB Computer Pick?

MLB picks are bet suggestions based on our computer's assessment of the game. Tons of betting data goes into a computer pick, including pitching matchups, injury reports, analytics, and even recent betting trends.

How To Use MLB Computer Picks

You can use the tables above to help with your bets during the MLB season. The first section includes free, computer-generated picks for daily Major League Baseball games. Baseball bettors can choose to follow the computer, fade the computer, or simply use our computer picks as one element of their betting strategy.

This page also tees up access to deeper betting trends. For example, if a club's run line is favored, you can check their ATS trends, potentially opening up some quality underdog bets.

If you're ready to get started with MLB betting, visit our dedicated page highlighting the best MLB betting sites.

Moneyline

This is the most common and easiest wager for a bettor to make when it comes to MLB picks. Basically, to win an MLB moneyline pick, you just have to choose which team will win the game.

It's simple: if you bet the White Sox moneyline over the Red Sox and Chicago wins, you win your bet.

Run line

The run line is another name for a point spread that you may be more familiar with in NBA and NFL betting. A point spread varies in the NFL and NBA from as little as 0.5 points up to double-digit spreads. A baseball run line is almost always a 1.5-point spread.

The favorite will be -1.5 while the underdog will be +1.5. At the end of the game, if you take away 1.5 runs from the favorite or add 1.5 runs to the underdog and they end up winning the game, you win your MLB pick against the spread.

Totals (Over/Under)

Another common wager is to bet on the total in baseball, which is a bet on the total runs scored in the baseball game. You are simply choosing whether the final score will be Over or Under that total. Betting the Over/Under on a matchup is a great way to get started in MLB score predictions.

Free Computer Picks by Odds Shark

More MLB Picks & Betting Tools

NRFI/YRFI MLB Picks

A new and emerging MLB betting market is the NRFI/YRFI bet. These are quick-hitters in which you make a wager on the O/U total of the first inning, typically set at 0.5 runs. Thus, the bet is coined as No Run First Inning or Yes Run First Inning. No need to wait a couple of hours to cash a bet when it could be done in 20 minutes or less.

First Five Innings MLB Picks

The above options, moneyline, run line, and Over/Under, can also be placed on the first five innings of a game rather than the full game. Many experienced bettors will use this approach because, typically, this will take bullpens out of the equation and make your job researching the game easier. After all, you can just focus on the starting pitchers.

MLB Picks And Parlays

If you want to combine multiple games into one mega wager, you may consider making a parlay bet. A parlay is when you pick two or more MLB games on one single betting ticket, which will increase the payout of your bet.

But it also comes with more risk, as each of those MLB picks must hit for your ticket to pay out. Our parlay calculator is a great tool to find out what your potential payout would be.

If you're looking for more MLB picks content, check out our consensus picks and prop bets pages to get your fix. While you're at it, head over to our MLB promos page to get the best bang for your buck.

MLB Player Props

Player props are a great way to hone in on an individual matchup for a game. These types of wagers will be individualized for a player: Will Shohei Ohtani hit a home run? Will Gerrit Cole get seven strikeouts? Will Paul Skenes allow two earned runs?

You simply choose whether this outcome will happen or not. Keeping up to date on daily pitching matchups and batters on a hot streak can give you a huge boost when placing player prop bets.

MLB Futures Picks

Lastly, prior to the season and even throughout the season, you can place futures bets on all the long-term awards and outcomes. You can lock in an MLB pick on who will win their division, which squad will win the World Series, or even who will win the Rookie of the Year, MVP, or Cy Young.

MLB Free Picks FAQs

When do we release our MLB picks?

Covers’ MLB picks release on game day. Some significant matchups like playoff games release in the days leading up to the game.

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Covers provides free MLB picks covering many markets, including run lines, totals, moneylines, player props, and more.