MLB Player Props & Best Bets for Today, September 22

Colby Marchio - Contributor at Covers.com
Colby Marchio • Betting Analyst 7+ years betting experience
Updated: Sep 22, 2026 , 11:48 AM ET • 4 min read

Jake Burger is in a prime boom spot tonight against Sean Manaea. Over his last 60 at-bats against lefties, the Rangers slugger is generating a 60% hard-hit rate and a 35% barrel rate, while posting a .731 SLG and .462 ISO.

MLB player props Jake Burger
Photo By - Reuters Connect. Texas Rangers first baseman Jake Burger (21) rounds the bases after hitting a two-run home run.

STOP! Do not cry! We still have plenty of MLB player props to get through on the final week and last full-slate Tuesday of the season.

Join me as I break down three of my favorite MLB picks for September 22, including why Jake Burger is ready to pop off against Sean Manaea.

Best MLB player props today

Player  Pick Odds
Rockies Kyle Freeland  Over 2.5 earned runs -151
Rangers MacKenzie Gore Over 1.5 walks allowed -141
Rangers Jake Burger Over 1.5 hits + runs + RBI -105
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Kyle Freeland Over 2.5 earned runs (-151)

Teams average roughly three runs in the first five innings, while the Colorado Rockies are allowing well over three runs in the first five innings at home this season.

Left-hander Kyle Freeland, who has the worst pitcher rating on Batters-Box’s current-season dataset, is giving up 3.5 runs per game at home this season. Overall, he has allowed 3.79 runs per outing (24 starts).

This evening, the veteran southpaw draws six elite-rated Arizona Diamondbacks hitters. On top of that, this lineup is on fire, posting a 115 wRC+, .775 OPS, and .341 wOBA over the last 12 games.

If you are not in the juice-paying business, alt to 3.5 earned runs, but I would rather have the better number than sweat out another run. 

  • Time: 8:40 p.m. ET
  • Where to watch: ARID, COLR

MacKenzie Gore Over 1.5 walks allowed (-141)

Texas Rangers left-hander MacKenzie Gore has been struggling to find the zone over his last couple of outings. He draws a New York Mets team that has been drawing walks at a solid clip as of late, too.

Paying $1.41 juice is not asking a lot when Gore sports a near-17% walk rate over his last five starts. He has also allowed at least three walks in five straight starts.

New York has been great at drawing walks against southpaws. In its last 60 at-bats against a left-hander, seven hitters own at least a 10% walk rate.

Gore may be on a short leash due to his command issues, but we could also see this prop go over in the first inning. Either way, these percentages are way too high to ignore. Do not pay more than -145.

  • Time: 8:05 p.m. ET
  • Where to watch: RSN, SNY

Jake Burger Over 1.5 hits + runs + RBI (-105)

I'm making another Mets vs. Rangers prediction, as Jake Burger finds himself in a feast spot against Mets southpaw Sean Manaea, who has a near-17% barrel rate in his last five starts.

Meanwhile, Burger has been torching left-handers. Against the last 60 lefties the Rangers slugger has faced, he is generating a 60% hard-hit rate and a 35% barrel rate, while owning a .731 SLG and .462 ISO.

Manaea, against the last 30 right-handed hitters he has faced, is allowing a 50% hard-hit rate and a 13.6% barrel rate. On top of that, they have a .317 xBA, .561 xSLG, and .267 ISO.

With how much hard contact Burger is generating and how much Manaea is allowing, if the big fella connects, it should be in the bleachers.

Take this down to -120.

  • Time: 8:05 p.m. ET
  • Where to watch: RSN, SNY
Colby Marchio's 2026 Transparency Record
  • Prop picks: 524-1031, +7.3 units

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Colby Marchio
Betting Analyst

Colby Marchio is a two-time DePaul alum and former Division 1 (club) baseball player who has been sports betting since 2019. Since graduating in 2021, he has worked throughout the media circuit, hosting and appearing on various television and radio shows while making countless guest appearances discussing Major League Baseball, college basketball, college football, and the National Football League.

A self-proclaimed numbers nerd, Colby may enjoy digging through the data even more than winning itself. That passion is why his two favorite sports to cover are college basketball and Major League Baseball. 

As for his favorite sportsbook, it is whichever one has the best price, or whichever one is not taxing him as an Illinois resident. 

You can find all of his plays and more @ColbyMBets on Twitter/X.

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