NFL Week 7 opens with a Thursday Night Football clash between AFC North rivals, the Pittsburgh Steelers and Cincinnati Bengals.
We've got another international contest on tap for Sunday morning, when the Los Angeles Rams and Jacksonville Jaguars face off at London's Wembley Stadium.
The biggest game on Sunday's slate is arguably the Philadelphia Eagles looking to avenge their upset loss to the New York Giants by taking on the Minnesota Vikings as road favorites.
The day wraps with the Atlanta Falcons and San Francisco 49ers on Sunday Night Football before giving way to another Monday doubleheader: Tampa Bay Buccaneers at Detroit Lions and Houston Texans at Seattle Seahawks.
Let's take a look opening numbers and early movement of the NFL Week 7 odds.
NFL odds Week 7
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
 Steelersvs  Bengals |
Bengals +5.5 | Steelers -270 Bengals +220 |
42.5 |
 Ramsvs  Jaguars |
Jaguars +3 | Rams -148 Jaguars +126 |
44.5 |
 Patriotsvs  Titans |
Titans +7 | Patriots -360 Titans +290 |
41.5 |
 Saintsvs  Bears |
Bears -4.5 | Saints +190 Bears -230 |
45.5 |
 Dolphinsvs  Browns |
Browns -2.5 | Dolphins +130 Browns -154 |
40.5 |
 Panthersvs  Jets |
Jets +1.5 | Panthers -130 Jets +110 |
42.5 |
 Eaglesvs  Vikings |
Vikings +2.5 | Eagles -134 Vikings +114 |
43.5 |
 Raidersvs  Chiefs |
Chiefs -11.5 | Raiders +530 Chiefs -750 |
45.5 |
 Giantsvs  Broncos |
Broncos -7 | Giants +270 Broncos -335 |
40.5 |
 Coltsvs  Chargers |
Chargers -1.5 | Colts +102 Chargers -120 |
48.5 |
 Commandersvs  Cowboys |
Cowboys +2.5 | Commanders -132 Cowboys +114 |
53.5 |
 Packersvs  Cardinals |
Cardinals +6.5 | Packers -310 Cardinals +250 |
44.5 |
 Falconsvs  49ers |
49ers -3 | Falcons +134 49ers -158 |
46.5 |
 Buccaneersvs  Lions |
Lions -4.5 | Buccaneers +198 Lions -240 |
52.5 |
 Texansvs  Seahawks |
Seahawks -3.5 | Texans +148 Seahawks -176 |
40.5 |
Lines as of 10-14
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Steelers vs Bengals odds (Thursday, 8:15 p.m., Prime Video)
Opening line
- Bengals +6.5
- Over/Under 40.5
- View full Steelers vs. Bengals odds and matchup
- Read our Steelers vs. Bengals picks and predictions (coming soon)
The Steelers opened as big as 6.5-point favorites for Thursday Night Football and that line settled at -5.5 across the industry. The vig on that is climbing, so a move to Pittsburgh -6 could be on the way. The Bengals have a notable injury to watch in pass rusher Trey Hendrickson, who left Week 6 (back). The total opened at 40.5 and jumped to 41.5 points.
Also see: full Thursday Night Football odds
Rams vs Jaguars odds (Sunday, 9:30 a.m., NFL Network)
Opening line
- Jaguars +3
- Over/Under 46.5
- View full Rams vs. Jaguars odds and matchup
- Read our Rams vs. Jaguars picks and predictions (coming soon)
It’s a very early wake-up call for the Rams, who face the Jaguars at Wembley Stadium in London in Week 7. Los Angeles opened as a 3-point neutral-site favorite but the ankle injury to star WR Puka Nacua could drag this line down. The total opened at 46.5 points and shrank to 45.5 O/U.
Patriots vs Titans odds (Sunday, 1:00 p.m., CBS)
Opening line
- Titans +6.5
- Over/Under 41.5
- View full Patriots vs. Titans odds and matchup
- Read our Patriots vs. Titans picks and predictions (coming soon)
The Patriots opened as 6.5-point road chalk in Tennessee and some books have gone to the key number of a touchdown on this spread. The Titans could be without WR1 Calvin Ridley after he left Week 6’s loss (hamstring). The total opened at 41.5 points.
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Saints vs Bears odds (Sunday, 1:00 p.m., FOX)
Opening line
- Bears -4.5
- Over/Under 45.5
- View full Saints vs. Bears odds and matchup
- Read our Saints vs. Bears picks and predictions (coming soon)
Chicago squeaked out a win on Monday but has a short week to prep for the Saints at home in Week 7. The Bears opened as 4.5-point favorites while the total hit the board at 45.5 points.
Dolphins vs Browns odds (Sunday, 1:00 p.m., CBS)
Opening line
- Browns -2.5
- Over/Under 40.5
- View full Dolphins vs. Browns odds and matchup
- Read our Dolphins vs. Browns picks and predictions (coming soon)
The Browns are 2.5-point home favorites hosting the Dolphins in Week 7. However, there were several injuries on both sides of the ball come out of Sunday’s game, including TE David Njoku. This Over/Under opened at 40.5 and dropped to 39.5 points.
Panthers vs Jets odds (Sunday, 1:00 p.m., FOX)
Opening line
- Jets -1.5
- Over/Under 44.5
- View full Panthers vs. Jets odds and matchup
- Read our Panthers vs. Jets picks and predictions (coming soon)
The Jets don’t get a break after a bad showing in London in Week 6. New York opened as a 1.5-point home favorite hosting Carolina and some books have moved this spread to -1, with an injury to WR Garrett Wilson standing out. The Over/Under hit the board at 44.5 points and is down to 43.5 O/U.
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Eagles vs Vikings odds (Sunday, 1:00 p.m., FOX)
Opening line
- Vikings +2.5
- Over/Under 42.5
- View full Eagles vs. Vikings odds and matchup
- Read our Eagles vs. Vikings picks and predictions (coming soon)
The Vikings have had two weeks to prepare for the Eagles and rest up a roster loaded with injuries. Minnesota is still unsure of its starting QB for this monster matchup, with J.J. McCarthy still on the mend. Philadelphia is coming off a mini bye after an upset loss to the Giants last Thursday and opened as 2.5-point road chalk. The total has bounced between 41.5 and 42.5 points since opening.
Raiders vs Chiefs odds (Sunday, 1:00 p.m., CBS)
Opening line
- Chiefs -10.5
- Over/Under 45.5
- View full Raiders vs. Chiefs odds and matchup
- Read our Raiders vs. Chiefs picks and predictions (coming soon)
The Chiefs came up big with a dominating win over Detroit on Sunday night and open as beefy 10.5-point favorites vs. the rival Raiders in Week 7. The total hit the board at 45.5 points.
Giants vs Broncos odds (Sunday, 4:05 p.m., CBS)
Opening line
- Broncos -7.5
- Over/Under 40.5
- View full Giants vs. Broncos odds and matchup
- Read our Giants vs. Broncos picks and predictions (coming soon)
The Broncos won a weird game over the Jets in London and now travel home to host the Giants, who are fresh off a Thursday upset of the Eagles. Denver opened as a 7.5-point favorite, but that number has dropped to a touchdown, with some shops below that key number to -6.5. The total hit the board at 40.5 points.
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Colts vs Chargers odds (Sunday, 4:05 p.m., CBS)
Opening line
- Chargers -1.5
- Over/Under 48.5
- View full Colts vs. Chargers odds and matchup
- Read our Colts vs. Chargers picks and predictions (coming soon)
The Chargers opened as 1.5-point home chalk against the Colts in Week 7. The Over/Under opened at 48.5 points and has bounced between that opener and 47.5 in the first 12 hours of action. Keep an eye on the Bolts’ laundry list of injuries, as some key offensive players could be back in action in Week 7.
Commanders vs Cowboys odds (Sunday, 4:25 p.m., FOX)
Opening line
- Cowboys +2.5
- Over/Under 53.5
- View full Commanders vs. Cowboys odds and matchup
- Read our Commanders vs. Cowboys picks and predictions (coming soon)
Washington is coming of a close loss on Monday and now faces this NFC East foes on the road. The Commanders opened as 2.5-point road chalk at Dallas with eyes on their banged-up receiving corps. The Cowboys are hoping they can get a star WR back in CeeDee Lamb in Week 7. The total opened at 53.5 points – the tallest total on the board.
Packers vs Cardinals odds (Sunday, 4:25 p.m., FOX)
Opening line
- Cardinals +6.5
- Over/Under 43.5
- View full Packers vs. Cardinals odds and matchup
- Read our Packers vs. Cardinals picks and predictions (coming soon)
The Packers didn’t exactly impress in their Week 6 win over Cincinnati, while the Cardinals kept fighting against the Colts despite star QB Kyler Murray watching from the sideline. Green Bay opened as a 6.5-point road favorite with the total at 43.5 points. On top of Murray’s health concerns, Arizona could be missing WR1 Marvin Harrison Jr. (concussion) in Week 7.
Falcons vs 49ers odds (Sunday, 8:20 p.m., NBC)
Opening line
- 49ers -3
- Over/Under 45.5
- View full Falcons vs. 49ers odds and matchup
- Read our Falcons vs. 49ers picks and predictions (coming soon)
The Falcons are coming off their biggest win of the season but have a short turnaround to get ready for the 49ers. Atlanta opened -3 and vig on the field goal is rising, indicating a possible hook coming later in the week. This total hit the board at 45.5 and jumped to 46.5 points. San Francisco is hoping to have QB Brock Purdy, WR Ricky Pearsall and TE George Kittle back in action this weekend.
Also see: full Sunday Night Football odds
Buccaneers vs Lions odds (Monday, 7:00 p.m., ABC/ESPN)
Opening line
- Lions -5.5
- Over/Under 52.5
- View full Buccaneers vs. Lions odds and matchup
- Read our Buccaneers vs. Lions picks and predictions (coming soon)
Detroit got smacked around by the Chiefs on Sunday night and has another tough matchup on Monday Night Football in Week 7. Tampa Bay comes to the Motor City as a 5.5-point road underdog. The extra day of rest will do both sides some good, as they have starters on both sides trying to get back on the field. The total opened at 52.5 and climbed to 53.5 points.
Also see: full Monday Night Football odds
Texans vs Seahawks odds (Monday, 10:00 p.m., ESPN)
Opening line
- Seahawks -3.5
- Over/Under 41.5
- View full Texans vs. Seahawks odds and matchup
- Read our Texans vs. Seahawks picks and predictions (coming soon)
Seattle opened as a 3.5-point home favorite for this Monday Night Football matchup with the Texans, who are coming off a bye. The Over/Under opened at 41.5 points and has since dipped to 40.5 O/U. Keep a close eye on the injury updates in a depleted Seattle secondary in Week 7.
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