NFL Picks Against the Spread for Every Week 11 Game Today

Chris Vasile breaks down his favorite NFL picks against the spread for Week 11, including the Los Angeles Chargers and Kansas City Chiefs.

Chris Vasile - Betting Analyst at Covers.com
Chris Vasile • Betting Analyst
Nov 16, 2025 • 09:28 ET • 4 min read
Detroit Lions quarterback Jared Goff (16) drops back to pass against the Tampa Bay Buccaneers.
Photo By - Imagn Images. Detroit Lions quarterback Jared Goff (16) drops back to pass against the Tampa Bay Buccaneers.

A wise man once said, “On any given Sunday, you’re gonna win or you’re gonna lose.”

And this season, that’s never felt truer. What we think we know makes no sense, and who teams think they are might just be an illusion.

Either way, we went 8-6 last week — let’s top that with our Week 11 NFL picks against the spread.

Week 11 NFL picks against the spread

Matchup Pick
Jets Jets vs Patriots Patriots    Jets (+11.5)
Commanders Commanders vs Dolphins Dolphins Dolphins (-2.5)
Chargers Chargers vs Jaguars Jaguars  Chargers (-2.5)
Buccaneers Buccaneers vs Bills Bills   Bills (+5.5)
Bears Bears vs Vikings Vikings Bears (+3)
Packers Packers vs Giants Giants    Packers (-7.5)
Texans Texans vs Titans Titans Titans (+7.5)
Panthers Panthers vs Falcons Falcons Falcons (-3.5)
Bengals Bengals vs Steelers Steelers Bengals (+5.5)
49ers 49ers vs Cardinals Cardinals Cardinals (+2.5)
Seahawks Seahawks vs Rams Rams Rams (-2.5)
Chiefs Chiefs vs Broncos Broncos Chiefs (-3.5)
Ravens Ravens vs Browns Browns Ravens(+8.5)
Lions Lions vs Eagles Eagles Lions (-1.5)
Cowboys Cowboys vs Raiders Raiders Cowboys (-3.5)

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Expert Week 11 NFL ATS picks

Jets vs Patriots: Jets Jets (+11.5)

Keeping with the theme of the opening monologue, nothing in this league makes sense, which is why the first-place New England Patriots will not cover double digits on a short week. They are coming off an emotional road win vs. Tampa Bay, and now have to face the lowly New York Jets, who also found the win column last week. Too many points. 

Read our full Jets vs. Patriots predictions.

Commanders vs Dolphins: Dolphins Dolphins (-2.5)

The Miami Dolphins beat the Bills, while the Washington Commanders gave up 44 to the Lions. I'm not saying the Miami will hang 44 on the Washington defense, but I don't see a way back for a Commanders team that's dropped five straight. 

Read our full Commanders vs. Dolphins predictions.

Chargers vs Jaguars: Chargers Chargers (-2.5)

One does not simply give up 26 fourth-quarter points to Davis Mills and expect a bettor to trust you a week later. The Los Angeles Chargers are a good football team with a real quarterback, and I expect them to drop 30+ on the Jacksonville Jaguars defense. 

Read our full Chargers vs. Jaguars predictions.

Buccaneers vs Bills: Bills Bills (-5.5)

If the Buffalo Bills have any sense of pride, they come out and lay a whooping on the Tampa Bay Buccaneers. They were embarrassed by the Dolphins, and that won't fly on their home turf. I'll trust them to bounce back in this spot against a depleted Bucs side. 

Read our full Buccaneers vs. Bills predictions.

Bears vs Vikings: Bears Bears (+3)

The Chicago Bears are playing some good football right now, and this is a revenge spot from their Week 1 loss to the Minnesota Vikings — a game they led 17-6 heading into the fourth quarter. 

Read our full Bears vs. Vikings predictions.

Packers vs Giants: Packers Packers (-7.5)

I was on the Eagles last week to beat the Green Bay Packers, and that cashed despite some god-awful football. Now, I will back the Packers to beat the coachless, Jaxson Dart-less, New York Giants, who would be better off losing and securing a high draft pick. 

Read our full Packers vs. Giants predictions.

Texans vs Titans: Titans Titans (+7.5)

The Houston Texans caught lightning in a bottle against a bad team last week, and while they may play another bad team this week, this is too many points. The Tennessee Titans are off a bye, and I believe they come out with some jump. 

Read our full Texans vs. Titans predictions.

Panthers vs Falcons: FalconsFalcons (-3.5)

I will die on this hill. The Carolina Panthers are not a good football team despite their 5-5 record. They've caught a couple of teams by surprise, and the Atlanta Falcons won't be one of them. The Falcons have too much offense for the Panthers to keep up with, and desperately need a win to stop their four-game losing skid. 

Read our full Panthers vs. Falcons predictions.

Bengals vs Steelers: Bengals Bengals (+5.5)

The last time these teams met, the Cincinnati Bengals won 33-31 as +5.5-point underdogs. I expect a similar result here. 

Read our full Bengals vs. Steelers predictions.

49ers vs Cardinals: Cardinals Cardinals (+2.5)

Both teams were lit up last week, giving up 42 and 44 points, respectively. I would prefer this spread to be +3, but at home, I think the Arizona Cardinals' offense has a bit more upside than the San Francisco 49ers'. 

Read our full 49ers vs. Cardinals predictions.

Seahawks vs Rams: Rams Rams (-2.5)

This may very well be the highest-scoring game of the week, but I trust the home side a bit more. Sam Darnold is primed for a stinker, and the Los Angeles Rams defense rates out better across the board. 

Read our full Chiefs vs. Broncos predictions.

Chiefs vs Broncos: Chiefs Chiefs (-3.5)

Offense wins out here. Luckily for the Kansas City Chiefs, they are off a bye and have Patrick Mahomes.

Read our full Chiefs vs. Broncos predictions.

Ravens vs Browns: Ravens Ravens (-8.5)

Don't let the Baltimore Ravens get hot. Once they do, they'll be hard to stop. I expect a thorough beating of the Cleveland Browns

Read our full Ravens vs. Browns predictions.

Lions vs Eagles: Lions Lions (+1.5)

This will be a very good football game (I say, with fingers crossed). Either way, I'll trust the Detroit Lions behind Jared Goff and Dan Campbell's aggressive play-calling. 

Read our full Lions vs. Eagles predictions.

Cowboys vs Raiders: Cowboys Cowboys (-3.5)

The Dallas Cowboys are coming off a bye, while the Las Vegas Raiders were held to seven points on Thursday against the Broncos. I know both teams have their issues, but I trust Dallas' offense to put up points more than I do whatever the Raiders are running out. 

My NFL ATS record is 77-72 this season for +0.2 units.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Chris Vasile Covers.com
Betting Analyst

Chris Vasile has been in the betting industry for well over a decade, honing his craft as a writer, editor, and handicapper. Chris has contributed betting and non-betting content for online publications such as ProSportsDaily and The Hockey Writers, in addition to Covers. With a keen interest in soccer, Chris has been featured on Covers' 'Before You Bet', BetMGM Network, and SportsGrid. He also runs his own YouTube channel — Game Day Wagers.

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