Giants vs 49ers TNF Prop Bets: Little Giants

James Bisson - Head of Content, Betting
James Bisson • Head of Content, Betting 16+ years betting experience
Updated: Sep 21, 2023 , 06:31 PM ET • 4 min read

Week 3 of the NFL season kicks off on Thursday with a clash between the Giants and 49ers. The Niners are heavy favorites but our TNF prop bets believe there are markets ripe for the picking. Read on to find out more!

The New York Giants escaped disaster last week, completing a 20-0 halftime comeback to steal a win against the presumed bottom-of-the-barrel Cardinals. The Week 3 odds have them traveling to take on the San Francisco 49ers, who have strung together two impressive wins to start the season. 

The Giants will embark on their trip without both their star running back Saquon Barkley and emerging left tackle Andrew Thomas, while San Francisco may be without breakout wideout Brandon Aiyuk.

Who will step up and emerge on the national stage for Thursday Night Football? TNF odds have the Niners tabbed as -10.5 point favorites with the total sitting at 44.5. 

Continue reading for free NFL prop picks and predictions for the Giants vs. 49ers Thursday Night Football game on September 21 and check out our full game preview in our Giants vs. 49ers predictions — and our Christian McCaffrey odds and props spotlight.

Giants vs 49ers TNF props

  • Mitchell Over 28.5 rush yards
  • Purdy Under 28.5 pass attempts
  • Bosa Over 0.75 sacks

Picks made on September 20 at 4:45 p.m. ET.
Read full analysis of each pick.

Best Thursday Night Football bonuses

FanDuel All Users
50% profit boost for one Giants/49ers bet! Claim Now

DraftKings All Users
50% profit boost for one Giants/49ers bet! Claim Now

bet365 All Users
50% profit boost for one Giants/49ers SGP! Claim Now

Pointsbet All Users
Power Hour: Bonus bets and boosted odds released 6-9 p.m. ET all weekend! Claim Now

Eligible USA locations only. Also, see our full list of best sportsbook promotions for 2023.
21+. Gambling Problem? Call 1-800-GAMBLER

Enjoying Covers content? Add us as a preferred source on your Google account Add as a preferred source on Google

Giants vs 49ers TNF props

Prop bet #1: Producing in relief

After playing 100% of the Niners' Week 2 snaps (and 85% of their Week 1 snaps), Kyle Shanahan admitted that he needed to spell Christian McCaffrey and noted "We definitely got to get Elijah [Mitchell] in there more and do better with our rotation than we did yesterday. That wasn’t the plan going in, it just ended up that way. I’ve got to make sure that doesn’t happen".

Elijah Mitchell has logged just five rushing attempts this season (all coming in Week 1), and didn't even take the field in the last game. But given Shanahan's comments, we should see a workload for Mitchell more in line with last year's.

In the four regular season games that Mitchell and McCaffrey played together last year, Mitchell averaged 9.8 carries and 59.5 rushing yards per game. Even in the two playoff games they played together last year (a time during which Shanahan would lean heaviest on his stars), Mitchell still handled 23 combined rushing attempts and had snap percentages of 22% (Wild Card round) and 33% (Divisional round).

Throw in the fact that this game has blowout potential (the Niners are favored by 10 at most books), and you have a recipe for Mitchell to find the field.

Elijah Mitchel prop: Over 28.5 rushing yards (-110 at DraftKings)

Prop bet #2: Purdy Pedestrian

Thursday Night Football can always be a bit wonky, and coaches of teams tend to play a bit safer and more conservatively in order to not strain their players too much - especially if they are expected to win or have established a large lead.

A perfect example of this is a Thursday Night Football game from last December - a game which Purdy actually played in. The Niners had built a 21-6 lead over the Seahawks by the middle of the third quarter and across their final 28 offensive plays (end-of-game kneel downs were excluded), they only attempted ten passes.

Purdy finished with 26 pass attempts for the game, a mark that is certainly low for him. In fact of the ten games (both regular season and playoffs) that he started and finished, he has only had less pass attempts in four of those games. Those four games were blowouts of 17, 23, 25, and 28

If we expect a blowout, we should expect Purdy to throw less.

Brock Purdy prop: Under 28.5 pass attempts (-130 at DraftKings)

Prop bet #3: Sack City

Nick Bosa got what he wanted when a five-year $170 million extension ended his holdout just before the season began. However, his performance thus far hasn't exactly made the extension look worth it in the small sample that is the 2023 season thus far.

Bosa has been held without a sack for the first two games, and the star EDGE rusher has not gone sack-less in back-to-back games since the 2021 season. Helping his cause is the fact that the Giants' offensive line will be shorthanded after it was announced left tackle Andrew Thomas will miss Thursday night's game.

And the offensive line has already had its fair share of troubles even before Thomas' departure, having surrendered ten sacks across the first two games already. That included seven alone to the Cowboys' defense, a defense that talent-wise profiles similarly to the Niners'.

Nick Bosa prop: Over 0.75 sacks (+100 at DraftKings)

Not intended for use in MA.
Affiliate Disclosure: Covers may receive advertising commissions for visits to a sportsbook or betting site
.

Kentucky: Sports betting is coming!

Kentucky sports betting will launch on September 28 — but you can pre-register now!
Check out the best Kentucky sports betting apps, as well as the best Kentucky sportsbook promos!

21+ and present in KY. Gambling Problem? Call 1-800-GAMBLER

Google News
Stay updated with the latest picks, odds, and news! Tap the star to add us to your favorites on Google News to never miss a story.

Pages related to this topic

James Bisson
Head of Content, Betting

James Bisson is the Editor-in-Chief at Covers. He has been a writer, reporter and editor for more than 20 years, including a nine-year stint with The Canadian Press and more than five years at theScore. He has covered dozens of marquee events including the 2010 Winter Olympics, the 2006 Stanley Cup final and Wrestlemania 23, and his work has appeared in more than 200 publications, including the Los Angeles Times, the Guardian, Yahoo! Sports, the Toronto Star and The Globe and Mail.

His book, “100 Greatest Canadian Sports Moments”, was a hardcover best-seller in Canada in 2008 and earned him appearances on CBC Radio and Canada AM. He has written more than 50 sportsbook reviews, more than 200 industry news articles, and dozens of other sportsbook-related content articles.

A graduate of the broadcast journalism program at Ryerson University (now Toronto Metropolitan University), James has been an avid bettor since the early 2000s, and cites bet365 as his favorite sports betting site due to its superior functionality and quick payouts. His biggest professional highlight: Covering Canada's first Olympic gold medal on home soil – and interviewing Bret Hart. Twice.

Popular Content

Covers is verified safe by: Evalon Logo GPWA Logo GDPR Logo GeoTrust Logo Evalon Logo