A fresh, shiny new NFL season is here, and the first jam-packed Sunday is upon us, and it comes with no shortage of injury concerns already.
We're tracking the latest NFL Week 1 injury updates and most pressing game-time decisions to assist with your NFL picks.
Latest NFL Week 1 injury updates
Updated at 6:56 p.m. ET on Sunday, Sept. 13.
- Malik Nabers active for Sunday Night Football: A knee injury cut Nabers' season short last year. Giants head coach John Harbaugh wouldn't fully commit to playing him in Week 1, but said "I think he's ready to go" earlier in the week. He practiced in full all week and was ultimately given the green light after testing his knee this afternoon.

Who will play in NFL Week 1?
Here are the latest updates on the most critical injury situations for Week 1.
| Game | Player(s) | Status | Latest update |
|---|---|---|---|
| 🟢 Active | Love suffered a high ankle sprain early in the preseason. But the reports about his availability throughout the week were progressively encouraging, and the highly touted rookie is ready to roll. | ||
| 🟢 Expected to practice | For a long while it's looked like Mahomes would play in Week 1, and head coach Andy Reid said "there's a good chance." He's been practicing in full all week too, so while there's no concrete word yet, Mahomes being under center seems highly likely. | ||
| 🟢 Active | After uncertainty swirled around the receiver and his knee, he was officially named active about 90 minutes before game time. |
Odds are correct at the time of publishing and are subject to change.
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