After getting hammered in the first two of a five-game road set, it doesn’t get easier for the Indiana Pacers, who square off with the Boston Celtics at TD Garden tonight.
My Pacers vs. Celtics predictions and NBA picks don't expect Indiana to keep up its end of the scoring bargain, ultimately dragging down the total, on Wednesday, January 21.
Pacers vs Celtics prediction
Pacers vs Celtics best bet: Under 227.5 (-110)
On Saturday, the Indiana Pacers put up their fewest points of the campaign in a 121-78 thrashing at the hands of the Pistons.
They followed that up by scoring just 104 points in a loss to the 76ers, turning it over a whopping 24 times.
Over their last five games, Indiana has scored 104 points or less four times – well below their 110.1 points per game average on the year, which ranks 29th, better than only Brooklyn.
Amazingly, one of those games was a win against these same Boston Celtics, who have lost three of five, with the C’s putting up just 98 points per game in those losses.
Still, in what was supposed to be a regroup year, Boston sits second in the East, powered by All-Star Jaylen Brown.
However, Brown did find his way onto the injury report with a hamstring injury, though he is listed as probable for Wednesday. The one loss to Indy was with Brown out of the lineup.
Indiana can’t score, and Boston owns the second-best scoring defense in the league, and third-best field goal shooting defense.
It’s no surprise, then, that the Under has hit in two of three meetings this season. Indiana has cashed the Under in six of its last seven, and the beat (and beatings) should go on in Beantown.
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Pacers vs Celtics same-game parlay
Brown was just named an All-Star starter for the first time in his career on Monday, and Indy is a good opponent to showcase his wares. He’s topped 30 points in both meetings with the Pacers, clearing this total once and falling short by a free throw the other.
And perhaps the books haven’t been following Aaron Nesmith too closely, setting his 3-point make line at 2.5. He’s gone Under that figure in six straight, and is just 2-for-22 from distance in his last three games.
Pacers vs Celtics SGP
- Under 227.5
- Jaylen Brown Over 30.5 points
- Aaron Nesmith Under 2.5 threes
Our "from downtown" SGP: Derrick White's Block Party
Neemias Queta has been a revelation for Boston’s improbable run this year, leading the team in rebounds at 8.2 per game. But he’s only topped his 8.5-board line in two of the last six, and has gone sub-9 in all three games vs. Indy this year.
We’ll finish with the Over for the best blocking guard in the business. Derrick White has had multi-block games in eight of his last 11, including a 7-swat effort against Utah.
Pacers vs Celtics SGP
- Under 227.5
- Jaylen Brown Over 30.5 points
- Aaron Nesmith Under 2.5 threes
- Neemias Queta Under 8.5 rebounds
- Derrick White Over 0.5 blocks
Pacers vs Celtics odds
- Spread: Pacers +10.5 (-110) | Celtics -10.5 (-110)
- Moneyline: Pacers +400 | Celtics -550
- Over/Under: Over 227 (-110) | Under 227 (-110)
Pacers vs Celtics betting trend to know
The Pacers have lost 15 straight road games vs teams with a winning record. Find more NBA betting trends for Pacers vs. Celtics.
How to watch Pacers vs Celtics
| Location | TD Garden, Boston, MA |
| Date | Wednesday, January 21, 2026 |
| Tip-off | 7:30 p.m. ET |
| TV | FDSN Indiana, NBC Sports Boston |
Pacers vs Celtics latest injuries
Not intended for use in MA.
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