Lakers vs Cavaliers Prediction, Picks & Odds for Tonight’s NBA Game

This could be LeBron's final trip to Cleveland, and you know The King will show out.

Jason Logan: Senior Betting Analyst at Covers
Jason Logan • Senior Betting Analyst
Jan 28, 2026 • 10:07 ET • 4 min read

NBA

Match starts: 7 hrs
CLE
53 %
LAL
47 %
EXPERT PICK - PROP
LeBron James o12.5  Rebounds and Assists (-105) LeBron James o12.5 Rebounds and Assists (-105)
Read Analysis
 LeBron James (23) brings the ball up court against the Dallas Mavericks during the game at the American Airlines Center.
Photo By - Reuters Connect. LeBron James (23) brings the ball up court against the Dallas Mavericks during the game at the American Airlines Center.

LeBron James returns to his hometown when the Los Angeles Lakers visit the Cleveland Cavaliers Wednesday.

James has helped Los Angeles win four of its last five games, contributing in various ways. Tonight, my Lakers vs. Cavaliers predictions call for a packed stat sheet from LeBron, focusing on his assists and rebounds.

Here are my best NBA picks for January 28.

Lakers vs Cavaliers prediction

Lakers vs Cavaliers best bet: LeBron James Over 12.5 rebounds+assists (-105)

At this point in his career, every trip to Cleveland could be LeBron James' last. Does that shrinking window make tonight’s game extra important to the former face of the franchise?

Maybe.

Since signing with the Los Angeles Lakers back in 2018, James has only played in Cleveland six times. On his first few trips back home, he put on a show with great effort.

But James’ role on the Lakers has changed in the past two seasons, becoming a complementary piece to Luka Doncic that does the little things.

That’s been especially true over the past month, as James worked his way into form after missing the start of the season. So far in January, he’s averaging 6.9 assists and 7.3 rebounds over 13 games.

The Cleveland Cavaliers come into Wednesday with a patchwork rotation, missing some key players on both ends of the floor. Cleveland’s trademark defense of past seasons is absent, with the team sitting in the middle of the league in defensive rating.

The Cavs are 23rd in opponent assist-to-FGM ratio and have also struggled to keep foes off the glass, rated 22nd in rebounds allowed. That’s compounded by the loss of leading rebounder Evan Mobley (8.8 rpg) for the next week (ankle).

James’s player projections for this homecoming call for another busy box score, with my numbers at 6.9 assists and 6.9 assists. That should have his combo prop of rebounds + assists priced at Over 12.5 -145.

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Lakers vs Cavaliers same-game parlay

The Lakers are rolling on this road trip and face a Cavs lineup that is getting shuffled due to injuries.

LeBron will let it fly from outside. While he’s not shooting well, he’s still taking 4.5 attempts from beyond the arc.

Lakers vs Cavaliers SGP

  • Lakers moneyline
  • LeBron James Over 12.5 rebounds+assists
  • LeBron James Over 1.5 threes

Our "from downtown" SGP: The King Has Returned

In six games in Cleveland as a Laker, James has posted a triple-double twice.

Lakers vs Cavaliers SGP

  • Los Angeles Lakers moneyline
  • LeBron James triple-double

Lakers vs Cavaliers odds

  • Spread: Lakers +3 | Cavaliers -3
  • Moneyline: Lakers +115 | Cavaliers -150
  • Over/Under: Over 235 | Under 235

Lakers vs Cavaliers betting trend to know

Los Angeles is 5-2 SU and ATS in non-conference road games this season. Find more NBA betting trends for Lakers vs. Cavaliers.

How to watch Lakers vs Cavaliers

Location Rocket Arena, Cleveland, OH
Date Wednesday, January 28, 2026
Tip-off 7:00 p.m. ET
TV ESPN

Lakers vs Cavaliers latest injuries

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Jason Logan Senior Industry Analyst Covers.com
Senior Betting Analyst

In his 20 years with Covers, lead NFL betting analyst; has seen it all and bet it all. Through the wild west of early Internet gambling to lobbying for legalized sports betting to our brave new wagering world, Jason has been a consistent source of actionable info and entertainment for squares and sharps alike. Since joining the Covers team back in 2005, he honed his handicapping skills to provide audiences with the most thorough insights, blending traditional capping methods with advanced modelling and predictive analysis. Jason has studied the ins and outs of the sports betting business, learning from some of the most successful gamblers in the industry and the biggest sportsbook operators on the planet. He is under center for Covers during NFL season as our top NFL expert, taking the points in his infamous NFL Underdogs column and representing the Covers Community at the Super Bowl. While he lives for football season, Jasons first love is basketball and that shows in his in-depth NBA, NCAA, and WNBA betting breakdowns. On top of being a mainstay in media from coast to coast; WPIX, PHL17, Fox 5 San Diego, WGNO, TSN, SportsNet, ESPN Radio; he had his analysis featured in USA Today, MSNBC, ESPN, the Wall Street Journal, CBS, Bloomberg, the L.A. Times, the New York Times and other major publications. You can also find JLo stuffing all the top picks and predictions he can into 10 minutes as the host of Covers; flagship podcast, The Sharp 600.

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