The Seattle Mariners will be looking to keep their winning ways alive tonight when they begin a series with the Minnesota Twins at Target Field.
My Mariners vs. Twins predictions will explain why I expect the M’s to take the series opener behind Luis Castillo on the bump.
Read more for my MLB picks for Monday, April 27.
Who will win Mariners vs Twins today: Mariners moneyline (-135)
The Seattle Mariners have captured four straight victories heading into tonight’s contest. Luis Castillo gets the ball tonight, and he’s found his form lately. The righty is also very familiar with this Minnesota Twins lineup.
Castillo has held their offense to a .195 average across 113 at-bats. Castillo has also allowed just three earned runs across his last two starts, and he’s only given up four earned runs on the road this year.
Seattle faces rookie Connor Prielipp this evening, who has held his own through three appearances. In his first start last week, Prielipp surrendered only two earned runs to the New York Mets.
However, he’s up against an M’s lineup which has scored 14 runs across its last two games.
I could see both guys throwing the ball well, but Castillo will be better, and Seattle will muster up enough offense to chase Prielipp relatively early.
COVERS INTEL: Minnesota’s bullpen has a horrid 4.85 ERA, and the Twins have also lost five straight games.
Mariners vs Twins Over/Under pick: Under 8.5 (+100)
While Seattle’s offense broke out a bit over the weekend, neither of these teams are scoring a ton of runs overall. The M’s are 22nd in runs scored, and they cashed the Under in two of the three games against the Cardinals.
The Twins also took part in a low-scoring series with the Tampa Bay Rays, with the Under hitting in all three matchups as well. They also scored just five runs in that series, and Minny comes up against a very good arm in Castillo.
The Mariners’ bullpen is also elite, compiling a 3.18 ERA. Most of the offense tonight will come from Seattle, but don’t expect a ton. Pitching will be the storyline of the first game of this series.
- ML/RL bets: 7-6, -2.94 units
- Over/Under bets: 7-6, +0.19 units
Mariners vs Twins odds
- Moneyline: Mariners -134 | Twins +114
- Run line: Mariners -1.5 | Twins +1.5
- Over/Under: Over 8.5 | Under 8.5
Mariners vs Twins trend
The Mariners have hit the Under in 10 of their last 13 away games (+6.80 Units / 48% ROI). Find more MLB betting trends for Mariners vs. Twins.
How to watch Mariners vs Twins and game info
| Location | Target Field, Minneapolis, MN |
| Date | Monday, April 27, 2026 |
| First pitch | 7:40 p.m. ET |
| TV | Mariners.TV, Twins.TV |
| Mariners starting pitcher | Luis Castillo (0-1, 5.01 ERA) |
| Twins starting pitcher | Connor Prielipp (0-0, 4.50 ERA) |
Mariners vs Twins latest injuries
Mariners vs Twins weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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