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Best NFL Picks Today

Find the best NFL bets today - Sept. 16, 2026. Free expert and computer picks for every NFL game.

New Computer Picks powered by Odds Shark

Predicted Score

DET logo
DET
DET

25.66 @ 27.69

BUF
BUF logo
BUF

Lions vs Bills · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

DET logo
DET
DET

25.66

+5.5 -115

o54.5 -107

+195

BUF logo
BUF
BUF

27.69

-5.5 -105

u55.0 -115

-225

Philadelphia @ Tennessee
Matchup Stats
Pittsburgh @ New England
Matchup Stats

Predicted Score

PIT logo
PIT
PIT

19.02 @ 24.77

NE
NE logo
NE

Steelers vs Patriots · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

PIT logo
PIT
PIT

19.02

+5.5 -109

o41.5 -108

+210

NE logo
NE
NE

24.77

-5.5 -105

u41.5 -107

-218

Minnesota @ Chicago
Matchup Stats

Predicted Score

MIN logo
MIN
MIN

18.31 @ 24.71

CHI
CHI logo
CHI

Vikings vs Bears · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

MIN logo
MIN
MIN

18.31

+5.5 -110

o47.5 -115

+200

CHI logo
CHI
CHI

24.71

-5.5 -105

u48.5 -111

-218

Carolina @ Atlanta
Matchup Stats

Predicted Score

CAR logo
CAR
CAR

22.24 @ 23.21

ATL
ATL logo
ATL

Panthers vs Falcons · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

CAR logo
CAR
CAR

22.24

-2.5 -109

o43.5 -110

-135

ATL logo
ATL
ATL

23.21

+2.5 -105

u44.5 -115

+121

Green Bay @ N.Y. Jets
Matchup Stats

Predicted Score

GB logo
GB
GB

24.68 @ 18.91

NYJ
NYJ logo
NYJ

Packers vs Jets · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

GB logo
GB
GB

24.68

-3.5 -105

o44.5 -110

-185

NYJ logo
NYJ
NYJ

18.91

+3.5 -106

u45.5 -115

+170

Top Projection Breece Hall u69.5 Rushing Yards (-115)
u70.5-120
New Orleans @ Baltimore
Matchup Stats

Predicted Score

NO logo
NO
NO

20.49 @ 26.38

BAL
BAL logo
BAL

Saints vs Ravens · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

NO logo
NO
NO

20.49

+8.5 -109

o46.5 -108

+330

BAL logo
BAL
BAL

26.38

-8.5 -105

u47.5 -115

-395

Top Projection Lamar Jackson u40.5 Rushing Yards (-115)
u41.5-118
Cincinnati @ Houston
Matchup Stats

Predicted Score

CIN logo
CIN
CIN

24.26 @ 25.68

HOU
HOU logo
HOU

Bengals vs Texans · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

CIN logo
CIN
CIN

24.26

+2.5 +100

o46.5 -110

+134

HOU logo
HOU
HOU

25.68

-2.5 -115

u46.5 -105

-148

Top Projection Joe Burrow o245.5 Passing Yards (-110)
o245.5-110
Cleveland @ Tampa Bay
Matchup Stats

Predicted Score

CLE logo
CLE
CLE

15.11 @ 22.80

TB
TB logo
TB

Browns vs Buccaneers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

CLE logo
CLE
CLE

15.11

+8.5 -109

o41.0 -114

+350

TB logo
TB
TB

22.80

-8.5 -105

u41.5 -110

-395

Top Projection Deshaun Watson o20.5 Rushing Yards (-140)
o20.5-140
Jacksonville @ Denver
Matchup Stats

Predicted Score

JAC logo
JAC
JAC

20.86 @ 24.35

DEN
DEN logo
DEN

Jaguars vs Broncos · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

JAC logo
JAC
JAC

20.86

+3.5 -135

o44.5 -118

+130

DEN logo
DEN
DEN

24.35

-3.5 -115

u45.5 -110

-145

Las Vegas @ L.A. Chargers
Matchup Stats

Predicted Score

LV logo
LV
LV

18.70 @ 25.57

LAC
LAC logo
LAC

Raiders vs Chargers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

LV logo
LV
LV

18.70

+6.5 -105

o43.5 -105

+250

LAC logo
LAC
LAC

25.57

-6.5 -110

u43.5 -107

-290

Seattle @ Arizona
Matchup Stats

Predicted Score

SEA logo
SEA
SEA

21.49 @ 21.13

ARI
ARI logo
ARI

Seahawks vs Cardinals · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

SEA logo
SEA
SEA

21.49

-3.5 -110

o40.5 -115

-195

ARI logo
ARI
ARI

21.13

+3.5 -105

u41.0 -108

+175

Top Projection Jacoby Brissett u5.5 Rushing Yards (-115)
u5.5-115
Miami @ San Francisco
Matchup Stats

Predicted Score

MIA logo
MIA
MIA

18.96 @ 27.14

SF
SF logo
SF

Dolphins vs 49ers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

MIA logo
MIA
MIA

18.96

+13.5 -110

o45.5 +100

+750

SF logo
SF
SF

27.14

-13.5 -105

u45.5 -108

-900

Top Projection Greg Dulcich o20.5 Receiving Yards (-140)
o20.5-140
Washington @ Dallas
Matchup Stats

Predicted Score

WAS logo
WAS
WAS

24.41 @ 28.75

DAL
DAL logo
DAL

Commanders vs Cowboys · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

WAS logo
WAS
WAS

24.41

+4.5 -113

o50.5 -105

+185

DAL logo
DAL
DAL

28.75

-4.5 -105

u50.5 -108

-200

Indianapolis @ Kansas City
Matchup Stats

Predicted Score

IND logo
IND
IND

20.17 @ 24.13

KC
KC logo
KC

Colts vs Chiefs · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

IND logo
IND
IND

20.17

+6.5 +100

o46.0 -110

+265

KC logo
KC
KC

24.13

-6.5 -115

u47.0 -114

-285

Top Projection Patrick Mahomes u15.5 Rushing Yards (-115)
u15.5-115
N.Y. Giants @ L.A. Rams
Matchup Stats

Predicted Score

NYG logo
NYG
NYG

19.94 @ 29.02

LA
LA logo
LA

Giants vs Rams · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

NYG logo
NYG
NYG

19.94

+7.5 -115

o47.5 -115

+295

LA logo
LA
LA

29.02

-7.5 +102

u48.5 -110

-345

Top Projection Jaxson Dart u29.5 Rushing Yards (-110)
u29.5-110
Detroit Lions image thumbnail DET @ Buffalo Bills image thumbnail BUF Thu, Sep 17 • 8:15 PM ET
Passing Yards
Jared Goff logo Jared Goff o263.5 Passing Yards (-115)
Best Odds
Pick made: 15 minutes ago
Dustin Saracini logo
Dustin Saracini
Senior Analyst

Expect Goff to air it out in what should be an absolute shootout between these two offenses on Thursday Night Football. Detroit's secondary gave up 410 yards through the air in Week 1, while the Bills' unit coughed up 274, paving the way for points - and strong quarterback play. When it comes to Goff, he went over this number 11 times last season, averaging roughly 39 pass attempts per game. If we get anywhere near that type of volume in a matchup projected for 54+ points, Goff will fly over this number.

Receiving Yards
Keon Coleman logo Keon Coleman o10.5 Receiving Yards (-111)
Best Odds
Pick made: 2 hours ago
Neil Parker logo
Neil Parker
Betting Analyst

The Lions secondary was exposed without veterans Kerby Joseph (knee) and Brian Branch (Achilles) for a league-high 410 passing yards by the New Orleans Saints, and now Detroit heads to Orchard Park to face Bills star QB Josh Allen. I’m anticipating Buffalo having its own success through the air, and in particular, Coleman to pick up 11 or more receiving yards. The third-year wideout was quiet in a Week 1 road game against a Houston Texans defense that allowed the lowest EPA per dropback and ranked second in pass defense DVOA in 2025, so Detroit presents a far better matchup at home. Plus, Coleman recorded 14.3 yards per reception and a 13.7 aDoT through his first two seasons.

View 19 Picks
Philadelphia Eagles image thumbnail PHI @ Tennessee Titans image thumbnail TEN Sun, Sep 20 • 1:00 PM ET
Receiving Yards
Carnell Tate logo
Carnell Tate o40.5 Receiving Yards (-120)
Projection 52.43 (Over)
Best Odds
Pick made: 23 minutes ago
EV Model Rating
Star rating: 5 out of 5
An extreme throwing game script is implied by the Titans being a giant -7-point underdog in this game.. The predictive model expects the Tennessee Titans as the 6th-most pass-oriented offense among all teams this week with a 59.4% pass rate, accounting for their underlying propensities and matchup dynamics.. Based on the game dynamics and the underlying tendencies of each team, this game is expected by the projections to see 130.1 offensive plays run: the 4th-most out of all the games this week.. Last year, the feeble Philadelphia Eagles defense has surrendered the most yards-after-the-catch in football to opposing wide receivers: a colossal 0.00 YAC.. When it comes to cornerbacks in defending pass-catchers, Philadelphia's CB corps has been easily exploitable last year, profiling as the 7th-worst in the NFL.
Receiving Yards
DeVonta Smith logo
DeVonta Smith o60.5 Receiving Yards (-120)
Projection 64.97 (Over)
Best Odds
Pick made: 27 minutes ago
EV Model Rating
Star rating: 4 out of 5
Our trusted projections expect the Philadelphia Eagles to run the 7th-most total plays among all teams this week with 65.4 plays, accounting for their underlying propensities and game dynamics.. The Eagles have played in the most "bad weather" (rain, snow, or 15+ mph wind) games in the NFL since the start of last season, which ought to result in increased pass volume, lower running volume, and improved offense effectiveness when facing better weather in this week's game.. With an impressive 98.0% Route Participation Rate (100th percentile) last year, DeVonta Smith places among the wide receivers with the most usage in the league.. In this contest, DeVonta Smith is forecasted by the projection model to place in the 89th percentile when it comes to WRs with 7.6 targets.. DeVonta Smith has put up a monstrous 86.0 air yards per game last year: 89th percentile among WRs.
View 10 Picks
Pittsburgh Steelers image thumbnail PIT @ New England Patriots image thumbnail NE Sun, Sep 20 • 1:00 PM ET
Total
Pittsburgh Steelers image thumbnail New England Patriots image thumbnail u42.5 (-110)
Best Odds
Pick made: 2 days ago
Neil Parker logo
Neil Parker
Betting Analyst

The Steelers are built for Unders, and the Patriots lack game-breaking talent on offense with wide receiver A.J. Brown (ankle) out and running back TreVeyon Henderson (ankle) still nursing an injury. Pittsburgh quarterback Aaron Rodgers completed just 60% of his passes for a pedestrian 5.6 yards per attempt in Week 1, and New England QB Drake Maye’s 5.4 YPA and 6.5 aDoT in the season opener don’t jump off the page, either. The Steelers also allowed the fourth-lowest EPA per play, with the Pats surrendering the seventh lowest ahead of Monday Night Football, so we’re landing a fair number on this Under given the lack of offensive explosiveness going against this pair of stout stop units.

Rushing Yards
Drake Maye logo
Drake Maye u23.5 Rushing Yards (-115)
Projection 1.97 (Under)
Best Odds
Pick made: 13 minutes ago
EV Model Rating
Star rating: 5 out of 5
The projections expect the New England Patriots offense to be the 6th-slowest paced team in the NFL (in a neutral context) at the present time, averaging 29.28 seconds per snap.. Last year, the poor Pittsburgh Steelers run defense has conceded a monstrous 4.12 adjusted yards-per-carry (YPC) to opposing rushing attacks: the 26th-largest rate in the league.
View 11 Picks
Minnesota Vikings image thumbnail MIN @ Chicago Bears image thumbnail CHI Sun, Sep 20 • 1:00 PM ET
Spread
Chicago Bears image thumbnail CHI -5.5 (-110)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

While Wentz was serviceable, I see more than two points separating him and Murry in terms of value to the spread. That’s especially true if the Bears can break away on the scoreboard and force Wentz to carry the load. Minnesota’s defense is dangerous but gave up a ton of yards to the Packers. If we take the Cheeseheads’ fourth-quarter collapse out of the equation, the Vikes stop unit was 21st in EPA allowed per play in the first three quarters. Murray’s chances of clearing concussion protocols seems slim when you look at his reaction to the hit. Once he’s officially ruled out, this spread jumps to Bears -6 or higher. Give me Chicago below the key number now.

Anytime Touchdown
Justin Jefferson logo
Justin Jefferson Score a Touchdown (Yes: +185)
Projection 0.52 (Yes)
Best Odds
Pick made: a minute ago
EV Model Rating
Star rating: 4 out of 5
The Vikings will be starting backup quarterback Carson Wentz in this contest, which usually means fewer pass attempts and more rushing.. At a -5.5-point disadvantage, the Vikings are underdogs in this game, suggesting more of a reliance on moving the ball through the air than their usual game plan.. Right now, the 4th-most pass-oriented offense in football near the goal line (60.9% in a neutral context) according to the model is the Minnesota Vikings.. Given the game dynamics and the underlying traits of each team, this contest is forecasted by the projection model to have 131.0 offensive plays run: the 2nd-highest number among all games this week.. Our trusted projections expect Justin Jefferson to be a much bigger part of his offense's passing attack near the goal line in this game (29.8% projected Red Zone Target Share) than he has been since the start of last season (24.6% in games he has played).
View 11 Picks
Carolina Panthers image thumbnail CAR @ Atlanta Falcons image thumbnail ATL Sun, Sep 20 • 1:00 PM ET
Total
Carolina Panthers image thumbnail Atlanta Falcons image thumbnail o43.5 (-111)
Best Odds
Pick made: 2 days ago
Shawn Krest logo
Shawn Krest
Betting Analyst

Stay Over up to 45.5. The Panthers answered all questions about their offense in the opener, and the Carolina defense didn't show it was capable of stopping anyone. The Panthers have set scoring records for the preseason Hall of Fame Game and the NFL Week One opener. 

Spread
Atlanta Falcons image thumbnail ATL +1.5 (-111)
Best Odds
Pick made: 2 days ago
Shawn Krest logo
Shawn Krest
Betting Analyst

Stick with Atlanta up until -1.5. Falcons running back Bijan Robinson carrying the ball against a Panthers' defense that gave up a half dozen rushing touchdowns in the opener is a bad matchup for Carolina. Atlanta's offense could also get a boost if Tua Tagovailoa can return from injury.

View 9 Picks
Green Bay Packers image thumbnail GB @ New York Jets image thumbnail NYJ Sun, Sep 20 • 1:00 PM ET
Total
Green Bay Packers image thumbnail New York Jets image thumbnail u44.5 (-111)
Best Odds
Pick made: yesterday
Ed Scimia logo
Ed Scimia
Betting Analyst

The New York Jets averaged just 17.6 ppg last year and while Geno Smith is an upgrade at quarterback, I'm unconvinced that he's going to improve the situation all that much at age 35. Meanwhile, the Jets defense will get pressure on a one-dimensional Green Bay Packers offense that totaled just 66 yards on the ground against the Vikings. I'm backing the Under down to 42.5 points.

Spread
New York Jets image thumbnail NYJ +3.5 (-111)
Best Odds
Pick made: yesterday
Ed Scimia logo
Ed Scimia
Betting Analyst

There's no denying it: the New York Jets looked downright competent in Week 1. Breece Hall ran for 102 yards, Geno Smith was efficient in the passing game, and the defense held the Tennessee Titans to -0.28 EPA per pass. At home, I like New York to cover against the Green Bay Packers as long as the spread stays above a field goal.

View 9 Picks
New Orleans Saints image thumbnail NO @ Baltimore Ravens image thumbnail BAL Sun, Sep 20 • 1:00 PM ET
Total
New Orleans Saints image thumbnail Baltimore Ravens image thumbnail u47.5 (-110)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

The New Orleans Saints looked dead in the water for the first 30 minutes of the 2026 season. They were 27th in EPA per play in the first half versus Detroit on Sunday before the Lions took their foot off the gas and found themselves in an overtime squeaker. New Orleans’ output looks better than it was, scoring six points in the extra frame (before missing the 2-point convert). The Baltimore Ravens hung 41 points on Indianapolis in Week 1 but took a hit in the receiving corps, losing Zay Flowers and Ja'Kobi Lane to injury. This group was already thin and could have Baltimore’s offense short and simple in Week 2. The Ravens ran at the second highest rate in the opener (58%), mainly due to protecting a big lead in the second half. But they could be forced into similar handoffs with the passing game missing pieces.

Passing Yards
Tyler Shough logo
Tyler Shough o231.5 Passing Yards (-115)
Projection 240.9 (Over)
Best Odds
Pick made: a minute ago
EV Model Rating
Star rating: 4 out of 5
The Saints are an enormous 8.5-point underdog in this week's contest, which points towards an extreme passing game script.. Based on their underlying tendencies and matchup dynamics, the leading projections forecast the New Orleans Saints to pass on 61.2% of their chances: the 4th-greatest clip on the slate this week.. The New Orleans Saints have run the 3rd-most plays in the NFL since the start of last season, totaling a colossal 60.4 plays per game.. The Baltimore Ravens defense has been something of pass funnel last year, inducing opposing teams to attempt the 2nd-most passes in the NFL (36.2 per game) last year.. Opposing teams have thrown for the 3rd-most adjusted yards in the NFL (249.0 per game) versus the Baltimore Ravens defense last year.
View 9 Picks
Cincinnati Bengals image thumbnail CIN @ Houston Texans image thumbnail HOU Sun, Sep 20 • 1:00 PM ET
Spread
Houston Texans image thumbnail HOU -2.5 (-110)
Best Odds
Pick made: 2 days ago
Jason Logan logo
Jason Logan
Senior Betting Analyst

The Bengals got four takeaways and still had to sweat out the Bucs in Week 1. Houston's defense bounces back and that offense is improved and always strong at home. The Texans were 9 for 18 on 3rd/4th down conversions and went 4/5 for TDs in the red zone. Cincy finished 2/5 in RZ and needed a defensive score and four FGM (two 50+ yarders) to get to 33 points, despite those extra possesions.

Passing Yards
Joe Burrow logo
Joe Burrow o250.5 Passing Yards (-110)
Projection 299.78 (Over)
Best Odds
Pick made: a minute ago
EV Model Rating
Star rating: 5 out of 5
This week's line suggests a throwing game script for the Bengals, who are -3-point underdogs.. Based on their underlying propensities and matchup dynamics, the model projects the Cincinnati Bengals to pass on 68.8% of their plays: the greatest frequency among all teams this week.. Given the game dynamics and the underlying play styles of each team, this contest is forecasted by the projection model to have 129.8 plays on offense called: the 5th-highest number out of all the games this week.. The passing attacks of both teams (including both volume and effectiveness) ought to benefit from the calm "weather" conditions (meaning zero wind) inside this dome, while run volume may slide.. Joe Burrow rates as one of the most accurate QBs in the league last year with a fantastic 69.8% Adjusted Completion%, grading out in the 88th percentile.
View 11 Picks
Cleveland Browns image thumbnail CLE @ Tampa Bay Buccaneers image thumbnail TB Sun, Sep 20 • 1:00 PM ET
Anytime Touchdown
Bucky Irving logo
Bucky Irving Score a Touchdown (Yes: -110)
Projection 0.72 (Yes)
Best Odds
Pick made: 11 minutes ago
EV Model Rating
Star rating: 4 out of 5
The Buccaneers rank as the 5th-most pass-focused team in football near the end zone (in a neutral context) this year with a 77.8% red zone pass rate.
Rushing Yards
Quinshon Judkins logo
Quinshon Judkins o44.5 Rushing Yards (-115)
Projection 67.26 (Over)
Best Odds
Pick made: 31 minutes ago
EV Model Rating
Star rating: 5 out of 5
Our trusted projections expect the Browns as the 10th-most run-centric offense on the slate this week with a 44.3% run rate, based on their underlying strategic approach and matchup dynamics.. As it relates to the defensive tackles' role in stopping the run, Tampa Bay's unit has been atrocious last year, grading out as the 3rd-worst in the league. in the league.
View 9 Picks
Jacksonville Jaguars image thumbnail JAC @ Denver Broncos image thumbnail DEN Sun, Sep 20 • 4:05 PM ET
Passing Attempts
Trevor Lawrence logo
Trevor Lawrence o31.5 Passing Attempts (-122)
Projection 34.45 (Over)
Best Odds
Pick made: 5 minutes ago
EV Model Rating
Star rating: 4 out of 5
The model projects the Jacksonville Jaguars as the 8th-most pass-heavy offense among all teams this week with a 60.1% pass rate, based on their underlying propensities and matchup dynamics.. Given the game dynamics and the underlying approaches of each team, this game is forecasted by the model to see 131.9 offensive plays called: the highest number among all games this week.. The Jaguars have run the 9th-most plays in football since the start of last season, totaling a massive 58.4 plays per game.. In this week's contest, Trevor Lawrence is expected by the projection model to wind up with the 5th-most pass attempts among all quarterbacks with 36.2. . Opposing offenses have averaged 34.4 pass attempts per game versus the Denver Broncos defense last year: 6th-most in the league.
Passing Yards
Bo Nix logo
Bo Nix o215.5 Passing Yards (-120)
Projection 252.42 (Over)
Best Odds
Pick made: 41 minutes ago
EV Model Rating
Star rating: 5 out of 5
Given their underlying play style and matchup dynamics, the model projects the Broncos to pass on 60.1% of their plays: the 8th-highest rate on the slate this week.. The leading projections forecast this game to have the most plays run out of all the games this week at 131.9 plays, given the play styles of each team and game dynamics.. The Broncos have run the 8th-most plays in football since the start of last season, totaling a staggering 58.7 plays per game.. The Jacksonville Jaguars defense has been a prominent pass funnel last year, leading opposing quarterbacks to attempt the most passes in the NFL (37.5 per game) last year.. The Denver Broncos O-line grades out as the 4th-best in the NFL last year in protecting the quarterback, which has a strong influence on all air attack metrics across the board.
View 10 Picks
Las Vegas Raiders image thumbnail LV @ Los Angeles Chargers image thumbnail LAC Sun, Sep 20 • 4:05 PM ET
Anytime Touchdown
Omarion Hampton logo
Omarion Hampton Score a Touchdown (Yes: -130)
Projection 0.76 (Yes)
Best Odds
Pick made: a minute ago
EV Model Rating
Star rating: 4 out of 5
Our trusted projections expect the Chargers to be the 8th-most pass-centric team in the NFL near the goal line (in a neutral context) at the present time with a 58.2% red zone pass rate.. The 7th-most plays in the NFL have been run by the Los Angeles Chargers since the start of last season (a colossal 59.5 per game on average).. The weatherman calls for 1-mph wind in this game. Low wind usually means increased pass volume, and reduced rush volume, increased touchdown potential, and better passing effectiveness.
Rushing Yards
Omarion Hampton logo
Omarion Hampton o63.5 Rushing Yards (-115)
Projection 79.14 (Over)
Best Odds
Pick made: 41 minutes ago
EV Model Rating
Star rating: 5 out of 5
This game's line implies an extreme rushing game script for the Chargers, who are a heavy favorite by 7 points.. The predictive model expects the Los Angeles Chargers as the 6th-most run-centric team among all teams this week with a 47.6% run rate, based on their underlying strategic approach and matchup dynamics.. The 7th-most plays in the NFL have been run by the Los Angeles Chargers since the start of last season (a colossal 59.5 per game on average).
View 6 Picks
Seattle Seahawks image thumbnail SEA @ Arizona Cardinals image thumbnail ARI Sun, Sep 20 • 4:25 PM ET
Receiving Yards
Jaxon Smith-Njigba logo
Jaxon Smith-Njigba o79.5 Receiving Yards (-115)
Projection 88.95 (Over)
Best Odds
Pick made: 3 minutes ago
EV Model Rating
Star rating: 5 out of 5
The Seahawks will be starting backup QB Drew Lock this week, which typically means fewer pass attempts and more rushing.. The pass games of both teams (in terms of both volume and effectiveness) figure to benefit from the calm "weather" conditions (as in zero wind) inside this dome, while run volume may decline.. In this week's contest, Jaxon Smith-Njigba is predicted by the predictive model to slot into the 99th percentile when it comes to wide receivers with 10.8 targets.. With a high 36.0% Target% (100th percentile) last year, Jaxon Smith-Njigba rates as one of the wideouts with the biggest workloads in the NFL.. Jaxon Smith-Njigba has accrued a massive 109.0 air yards per game last year: 98th percentile when it comes to wideouts.
Passing Yards
Jacoby Brissett logo
Jacoby Brissett o215.5 Passing Yards (-115)
Projection 240.43 (Over)
Best Odds
Pick made: 19 minutes ago
EV Model Rating
Star rating: 5 out of 5
A passing game script is indicated by the Cardinals being a -4-point underdog in this week's game.. The predictive model expects the Arizona Cardinals as the 3rd-most pass-focused team among all teams this week with a 62.8% pass rate, based on their underlying strategic approach and matchup dynamics.. The 4th-largest volume of plays in the league have been run by the Arizona Cardinals since the start of last season (a staggering 60.0 per game on average).. The Seattle Seahawks defense has been a prominent pass funnel last year, leading opposing quarterbacks to attempt the 4th-most passes in football (36.1 per game) last year.. Jacoby Brissett grades out as one of the best quarterbacks in the league last year, averaging a stellar 220.0 adjusted yards per game while ranking in the 90th percentile.
View 7 Picks
Miami Dolphins image thumbnail MIA @ San Francisco 49ers image thumbnail SF Sun, Sep 20 • 4:25 PM ET
Anytime Touchdown
Christian McCaffrey logo
Christian McCaffrey Score a Touchdown (Yes: -180)
Projection 1.26 (Yes)
Best Odds
Pick made: a minute ago
EV Model Rating
Star rating: 4 out of 5
The 49ers rank as the 4th-most pass-centric offense in football near the end zone (context-neutralized) this year with a 80.0% red zone pass rate.. The 10th-largest volume of plays in the NFL have been called by the San Francisco 49ers since the start of last season (a colossal 58.3 per game on average).. When it comes to air yards, Christian McCaffrey grades out in the lofty 100th percentile among RBs last year, averaging an astounding 21.0 per game. (due to most of their targets being behind the line of scrimmage, this is far more remarkable than it sounds since most RBs have negative air yards).. Christian McCaffrey slots into the 100th percentile among running back WOPR (Weighted Opportunity Rating—an advanced stat that weighs high-value offensive involvement) with a superb 41.1 figure last year.. Christian McCaffrey ranks in the 100th percentile among RBs when it comes to catching touchdowns last year, averaging a terrific 0.35 per game.
Rushing Yards
Brock Purdy logo
Brock Purdy u10.5 Rushing Yards (+115)
Projection 1.25 (Under)
Best Odds
Pick made: 29 minutes ago
EV Model Rating
Star rating: 5 out of 5
Given the game dynamics and the underlying approaches of each team, this game is projected by our trusted projection set to have just 121.7 offensive plays run: the fewest out of all the games this week.
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Washington Commanders image thumbnail WAS @ Dallas Cowboys image thumbnail DAL Sun, Sep 20 • 4:25 PM ET
Anytime Touchdown
CeeDee Lamb logo CeeDee Lamb Score a Touchdown (Yes: +120)
Best Odds
Pick made: 2 hours ago
Jason Logan logo
Jason Logan
Senior Betting Analyst

The reason I gravitate to Lamb over Pickens in Week 2 is Washington’s new defensive coordinator Daronte Jones and his blitz-happy approach. He blitzed at the fifth highest rate in Week 1 (37.5% up from 23.5% in 2025). Dak Prescott is exceptional at recognizing and exposing the blitz, most often finding Lamb on quick reads for yards after the catch. He has six touchdowns in 11 career games versus Washington and multiple projections have Lambs’s TD probability as high as 60% on Sunday.

Receiving Yards
Terry McLaurin logo Terry McLaurin o49.5 Receiving Yards (-120)
Best Odds
Pick made: 3 hours ago
Jason Logan logo
Jason Logan
Senior Betting Analyst

Rember in the offseason when Commanders new offensive coordinator David Blough said he wanted to get Terry McLaurin 10 targets a game? Well, Blough came up six short of that target talk in Week 1. McLaurin drew only four balls, catching two for just 14 yards versus Philadelphia. The Eagles presented a tougher challenge than this Cowboys secondary, which comes into Week 2 without starting safety Malik Hooker. McLaurin has gone for at least 50 yards in six straight matchups with Dallas and had 50+ in nine of 12 career meetings. Week 2 projections all sit north of 50 yards with most at 60+ and my number at 63 yards.

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Indianapolis Colts image thumbnail IND @ Kansas City Chiefs image thumbnail KC Sun, Sep 20 • 8:20 PM ET
Passing Yards
Patrick Mahomes logo
Patrick Mahomes u220.5 Passing Yards (-115)
Projection 204.66 (Under)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 5 out of 5
This week's spread implies a rushing game script for the Chiefs, who are favored by 6.5 points.. Based on their underlying strategic approach and matchup dynamics, the projections expect the Kansas City Chiefs to pass on 54.0% of their chances: the 7th-lowest rate on the slate this week.
Receiving Yards
Rashee Rice logo
Rashee Rice u54.5 Receiving Yards (-114)
Projection 50.99 (Under)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
This week's spread implies a rushing game script for the Chiefs, who are favored by 6.5 points.. Based on their underlying strategic approach and matchup dynamics, the projections expect the Kansas City Chiefs to pass on 54.0% of their chances: the 7th-lowest rate on the slate this week.. Our trusted projections expect Rashee Rice to be a much smaller piece of his team's air attack in this game (23.0% projected Target Share) than he has been since the start of last season (28.6% in games he has played).. With a poor 0.00 yards-after-the-catch (YAC) (1st percentile) last year, Rashee Rice has been among the leading wide receivers in the league in the league in picking up extra yardage.
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New York Giants image thumbnail NYG @ Los Angeles Rams image thumbnail LA Mon, Sep 21 • 8:15 PM ET
Game Prop
Los Angeles Rams image thumbnail o27.5 Team Total (-120)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

Sean McVay is an excellent game planner with added time he'll work out the kinks on this offense. Matthew Stafford couldn’t get going against the 49ers but faces a softer stop unit from the Giants. New York’s defense looked much better than it truly was in Week 1, due to the offense grinding out gains and chewing up TOP. The Cowboys offense only had two second half possessions and while it was limited in action, Dallas ranked out well in terms of advanced metrics like EPA per play DVOA. This is a fast track indoor at SoFi Stadium and it doesn’t seem likely that L.A.’s offense gets bottled up for a second straight game. 

Passing Yards
Jaxson Dart logo
Jaxson Dart o210.5 Passing Yards (-115)
Projection 227.5 (Over)
Best Odds
Pick made: a minute ago
EV Model Rating
Star rating: 5 out of 5
An extreme passing game script is indicated by the Giants being a big -7-point underdog this week.. The 6th-highest number of plays in the league have been called by the Giants since the start of last season (a staggering 59.7 per game on average).. The pass attacks of both teams (as it relates to both volume and effectiveness) stand to benefit from the calm weather conditions (1-mph wind) being forecasted in this game, while ground volume may drop.. The Rams defense has been a glaring pass funnel last year, allowing opposing offenses to attempt the 6th-most passes in the league (34.4 per game) last year.. Last year, the poor Los Angeles Rams defense has given up the most yards-after-the-catch in the league to the opposing side: a massive 0.00 YAC.
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For every matchup in an NFL season, our NFL computer produces selections for a variety of different betting angles. Our computer picks are based on a proprietary algorithm that values each team in the current week to produce moneyline, spread, and point total selections.

The table above, below the game picks, tracks our NFL computer's results over the last 100 games, outlining the record and profit for selections, based on $100 unit size. We track the profit based on both opening and closing lines for every matchup.

How to Use NFL Computer Picks

The easiest way to utilize our computer picks is to simply follow our selections for every matchup, what you'd call ailing the computer." But there are other ways to utilize our NFL computer picks, as well.

You can use our NFL computer as a jumping-off point to do more research into specific lines, cross-referencing with expert picks, which can be found above the selections for some matchups, recent NFL betting trends, and more.

As well, you can gauge the confidence of the matchup. The larger the projected score, the more confident the computer is in a specific pick.

Or, if you want to implement a system, betting only on underdogs, for example, you can look for matchups in which our computer likes the underdog to inform which picks you're going to hone in on for a given week.

We have these computer picks for every sport you're looking to wager on, as well:

Free Computer Picks by Odds Shark

Moneyline

NFL moneyline picks are the simplest way to get in on the NFL action. All you have to do is simply bet on which team you think will win the game.

For moneyline picks, the favorite is represented with a minus sign (-) in front of the odds, while the underdog has a plus (+). However, you don't get the same profit for picking an underdog compared to a favorite. If the favored team is -120, a $100 bet on them would pay out $80 in profit and $180 total, if they win the game. The underdog winning at +150 would pay out a $150 profit, $250 total.

We have a complete breakdown of how to read NFL moneyline odds for these NFL computer picks.

Spread

While moneyline picks are the simplest, picking NFL games against the spread is probably the most common wager for regular NFL bettors.

To bet an NFL spread, you wager on whether a team will win by a certain number of points or more or if they'll lose by fewer points than the spread. For example, if the spread is -6.5 for the New England Patriots, you would win the bet if they win the game by 7 points or more. Or if a team is +6.5, you're betting on if they'll win outright or lose by fewer than 6.5 points.

There is a correlation between moneyline odds and the spread, as books set these lines based on the same information.

You can read more about NFL spreads here.

Totals (Over/Under)

If you aren’t entirely sold on which NFL team will win or cover in an NFL game, you can still use our NFL computer picks to bet on the point total.

As opposed to taking a side, in total or Over/Under betting, you wager on whether both NFL teams will combine for a final score of more than (Over) or less than (Under) the total number of points set by oddsmakers.

The computer picks, and your handicapping of totals is more about how you think both teams will score points, not which team has the edge to win.

More NFL Picks & Betting Tools

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NFL Free Picks FAQs

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Covers NFL picks are released two to three days before each game on the NFL schedule.

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Covers provides free NFL picks covering many markets, including point spreads, totals, moneylines, player props, and more.