Week 2 closes with the preseason Super Bowl favorites looking to bounce back against the New York Giants, who kicked off the John Harbaugh era with an encouraging victory in Week 1.
Some of our Giants vs. Rams expert picks expect the Los Angeles Rams to look more like themselves on Monday Night Football, while some of our other NFL picks are more skeptical. We break down both sides below.
Giants vs Rams expert picks
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 Probability |
|
|---|---|
 Josh Inglis: Jaxson Dart 30+ rushing yards |
56% |
 Dustin Saracini: Matt Stafford 250+ passing yards |
49% |
 Joe Osborne: Rams -7.5 |
47% |
 Jon Metler: Giants +7.5 |
54% |
Percentages courtesy of Kalshi, one of the best prediction market apps.
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Josh Inglis' expert pick: Jaxson Dart 30+ rushing yards
Price: 56% at Kalshi
Jaxson Dart isn't getting his rushing production scaled properly. He scrambled five times last week and added three designed runs for 54 yards. He also had three kneel-downs and lost five total yards, all in a game where he led wire-to-wire.
He'll likely be playing from behind in this game, increasing his passing rate, which should in turn increase his scrambling chances. He also likely won't lose five yards on kneel-downs as a touchdown underdog. The Covers prop projections are calling for 37.6 rushing yards, and Dart to be the third-most active QB rusher in Week 2 with 7.2 carries.
Dustin Saracini’s expert pick: Matt Stafford 250+ passing yards
Price: 49% at Kalshi
You have to think the debacle in Australia will be Matt Stafford's worst game of the season — and there's nothing like some home cooking. He averaged nearly 300 yards per game at home in 2025 and is in a prime bounce-back spot after over a week of rest for this Week 2 matchup.
This New York Giants secondary held Dak Prescott to 175 yards in Week 1, but the Rams are an entirely different monster — expect Stafford to right the ship in prime time.
Joe Osborne's expert pick: Rams -7.5
Price: 47% at Kalshi
Expect an A+ response from the Los Angeles Rams after their silly Australia travel strategy blew up in their face, leading to an embarrassing result and perhaps the worst performance of the McVay/Stafford era.
Bouncing back is in their DNA as they enter MNF on a 7-1 ATS run in their last eight games after an outright loss. The Giants deserve credit for an impressive opener, but there are levels to this. L.A. entered the season viewed as the league’s clear-cut best team and was -9.5 on the lookahead. Now rested and pissed off, expect the Rams to lay the smack down on the young Giants.
Jon Metler’s expert pick: Giants +7.5
Price: 54% at Kalshi
Give me the Giants catching 7.5 points on Monday Night Football, as I make them closer to a 6-point underdog in this matchup. I think everyone expects the Rams to bounce back, but I saw a level of toughness and identity from this Giants team that really grabbed my attention in their first game under John Harbaugh.
Matthew Stafford is one of the few MVP candidates who doesn't bring much to the table with his legs and relies almost entirely on being a pocket passer. That pocket might not be as clean as he'd like with Brian Burns, Abdul Carter, and Arvell Reese coming off the edge.
I think this Giants defense can make Stafford uncomfortable and prevent the Rams from moving the ball up and down the field at will, which should keep this game within the number. We saw what this defense did to George Pickens and CeeDee Lamb in Week 1, and I expect New York to make life difficult for Stafford.
How to watch Giants vs Rams
| Location | SoFi Stadium, Los Angeles, CA |
| Date | Monday, Sept. 21, 2026 |
| Kickoff | 8:20 p.m. ET |
| TV | ESPN/ABC |
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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