Anytime Touchdown Scorer Giants vs Patriots Prediction: TD Picks for Monday Night Football Week 13

TreVeyon Henderson has been one of the best running backs after contact, and he'll be the go-to option inside the red zone when the Patriots face a porous Giants defense.

Trevor Knapp - Betting Analyst at Covers.com
Trevor Knapp • Betting Analyst
Nov 30, 2025 • 13:30 ET • 4 min read
TreVeyon Henderson New England Patriots NFL
Photo By - Imagn Images. New England Patriots running back TreVeyon Henderson (32) celebrates a touchdown.

A cross-conference showdown is set for Monday Night Football, as the 10-2 New England Patriots host the 2-10 New York Giants at Gillette Stadium.

TreyVeyon Henderson has emerged as New England's clear-cut No. 1 running back, and the rookie headlines my favorite Giants vs. Patriots anytime touchdown picks for Monday, December 1. 

For even more NFL picks, make sure to check out our full Giants vs. Patriots predictions!

Giants anytime touchdown pick

Theo Johnson (+260 at bet365)

Injuries have piled up all year for the New York Giants' offense, and that has resulted in tight end Theo Johnson boasting a team-leading 30% target rate in the red zone. 

Johnson was targeted twice in the RZ last week against Detroit, and he's been one of Jaxson Dart's favorite weapons inside the 20s. From Weeks 4 through 10, with Dart starting, Johnson caught four touchdown passes from the rookie pivot.

Receivers Wan’Dale Robinson and Darius Slayton are both listed as questionable for this prime-time matchup, and with Dart returning under center on MNF, Johnson will be in line to reap the benefits in Foxborough.

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Patriots anytime touchdown pick

TreVeyon Henderson (-115 at bet365)

Despite starting the season as RB3 behind Rhamondre Stevenson and Antonio Gibson, TreVeyon Henderson has established himself as the lead back for the New England Patriots.

After Stevenson missed three straight games with turf toe starting in Week 9, Henderson has averaged 16.3 carries over his past four contests, boasting multi-score outings against the Buccaneers and Jets. 

Week 12 saw Henderson log 19 first-half snaps compared to Stevenson's nine, and the former Ohio State standout will feast on a Giants defense that is allowing a league-worst 5.9 yards per rushing attempt. 

Henderson currently sports a team-leading six touchdowns on the season, with five of them coming over his last three games. He’s also been targeted nine times through the air during that stretch, and I expect him to keep the production rolling at home.

Odds are correct at the time of publishing and are subject to change.
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Trevor Knapp - Covers
Betting Analyst

Trevor joined the Covers content team as a publishing editor in early 2022. Growing up in Vancouver, he studied Broadcast and Online Journalism at the British Columbia Institute of Technology (BCIT), and interned with TSN and Sportsnet Radio while also writing for the Daily Hive.

An avid bettor of the MLB, NFL, and CFL, Trevor advises his fellow sports bettors to leave their hearts at the door and not hesitate to fade their favorite team. It's a strategy he follows regularly as an apathetic Indianapolis Colts and Toronto Blue Jays fan.

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