The Detroit Tigers have had a miserable time away from Comerica Park, losing eight of 10 road games this season.
My Tigers vs. Red Sox predictions and MLB picks expect those struggles to continue in Boston on Friday, April 17.
Who will win Tigers vs Red Sox tonight: Red Sox (-130)
Ranger Suarez has had a difficult start to his Boston Red Sox career, but that coincides with very tough competition.
He has faced the Astros, Padres, and Cardinals. The Astros sit fourth in runs per game while the Padres sit 11th, and the Cardinals rank seventh in wRC+ against left-handed pitchers.
Suarez should get a little bit of relief against the Detroit Tigers. They've hit just .213 off lefties and rank 22nd in wRC+.
While most of the Red Sox top bats are lefties, they do have some good righties — most notably Willson Contreras and Ceddanne Rafaela — who could cause problems for Casey Mize.

Tigers vs Red Sox Over/Under pick: Under 8 (-120)
Suarez owns a 3.74 xFIP, which is well below his 5.02 ERA. He hasn’t pitched as poorly as the results suggest — and I’ve already highlighted the difficult competition he faced.
The Tigers are hitting .216 with a .083 ISO on the road and cold weather is expected, making this a good spot for Suarez to get back on track.
Mize owns a solid 3.85 xFIP and has done a good job of neutralizing left-handed bets, setting him up for a quality start against Boston.
Both bullpens are also well-rested, so the managers will have plenty of options to help limit runs.
- ML/RL bets: 1-3, -2.82 units
- Over/Under bets: 0-4, -4.67 units
Tigers vs Red Sox odds
- Moneyline: Detroit +122 | Boston -127
- Run line: Detroit +1.5 (-186) | Boston -1.5 (+178)
- Over/Under: Over 8.5 (+117) | Under 8.5 (-122)
Tigers vs Red Sox trend
The Red Sox have hit the Under in 14 of their last 22 games at home (+6.45 Units / 27% ROI). Find more MLB betting trends for Tigers vs. Red Sox.
How to watch Tigers vs Red Sox and game info
| Location | Fenway Park, Boston, MA |
| Date | Friday, April 17, 2026 |
| First pitch | 7:15 p.m. ET |
| TV | Apple TV |
| Tigers starting pitcher | Casey Mize (1-1, 3.94 ERA) |
| Red Sox starting pitcher | Ranger Suarez (1-1, 5.02 ERA) |
Tigers vs Red Sox latest injuries
Tigers vs Red Sox weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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