The Los Angeles Dodgers (75%) have enjoyed unmatched success against sub .500 teams this season, posting a 61-26 record.
They're not playing for anything in the standings, but my Dodgers vs. Giants predictions are sure they want to stay sharp heading into the playoffs. That shouldn't be a difficult task against a San Francisco squad littered with minor-league players.
Let's dive deeper into my MLB picks for this afternoon game on Saturday, Sept. 26.
Who will win Dodgers vs Giants today: Dodgers -2.5
For help understanding probabilities, see our odds calculator.
I’m laying the -2.5 with the Los Angeles Dodgers up to 53%.
Blake Snell has conceded only four runs over his last 35 innings. He has pitched lights-out, and should effortlessly carve up a San Francisco Giants team playing without a single batter from its Opening Day lineup.
Dodgers manager Dave Roberts will continue to start their regular hitters in an effort to stay sharp before their first-round series.
It is all systems go at the plate, and Matt Wilkinson’s 42.9% hard-hit rate could get him into trouble.
COVERS INTEL: The Dodgers lead the majors in xSLG vs. southpaws, making them the perfect candidate to capitalize on Wilkinson's inability to limit hard contact.
Dodgers vs Giants Over/Under pick: Under 7.5
I like the Under to 55%.
The Giants rank 24th in hard-hit percentage, 26th in xSLG, and have struck out nearly 25% of the time against southpaws in September.
Their run production has continued to tumble as they’ve shut players down for the year. They’ve averaged 2.1 runs over their last seven games, and scored two or fewer five times. They won’t contribute much.
While the Dodgers still want to stay sharp, this game doesn’t carry any weight. The conditions are also favorable to pitchers at Oracle Park.
I project a 5-1 type of game, which would check both boxes.
Dodgers vs Giants home run prediction: Teoscar Hernandez
Teoscar Hernandez lives to face left-handed pitching. He's performed very well against them over the years, and has caught fire down the stretch of the regular season.
Hernandez posted a .400 average with a .325 ISO and 26.5% barrel rate vs. lefties over the last 30 games. Those numbers put him in the elite of the elite.
Wilkinson throws fastballs nearly 60% of the time facing righties. That plays directly into the hands of Hernandez, who is sporting a .450 ISO and nearly 65% hard-hit rate vs. fastballs in the past 30 games.
- ML/RL picks: 127-101, +2.36 units
- Over/Under picks: 119-103-6, +2.11 units
Dodgers vs Giants weather
The temperature is expected to sit in the low 60s, albeit with winds blowing out. Still favorable to the pitchers.
Dodgers vs Giants odds
- Moneyline: Dodgers 75% | Giants 26%
- Run line: Dodgers -2.5 (50%) | Giants +2.5 (51%)
- Over/Under: Over 7.5 (49%) | Under 7.5 (52%)
Dodgers vs Giants trend
Los Angeles has hit the Under in 10 of its last 15 road games (+6.65 units, 40% ROI). Find more MLB betting trends for Dodgers vs. Giants.
How to watch Dodgers vs Giants and game info
| Location | Oracle Park, San Francisco, CA |
| Date | Saturday, Sept. 26, 2026 |
| First pitch | 4:05 p.m. ET |
| TV | SportsNet LA, NBC Sports Bay Area |
| Dodgers starting pitcher | Blake Snell (4-1, 1.86 ERA) |
| Giants starting pitcher | Matt Wilkinson (1-3, 3.65 ERA) |
Dodgers vs Giants latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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