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Best NFL Picks Today

Find the best NFL bets today - Sept. 16, 2026. Free expert and computer picks for every NFL game.

New Computer Picks powered by Odds Shark

Predicted Score

DET logo
DET
DET

25.91 @ 26.02

BUF
BUF logo
BUF

Lions vs Bills · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

DET logo
DET
DET

25.91

+5.5 -115

o54.0 -110

+190

BUF logo
BUF
BUF

26.02

-5.5 -105

u54.5 -110

-215

Philadelphia @ Tennessee
Matchup Stats

Predicted Score

PHI logo
PHI
PHI

23.62 @ 15.37

TEN
TEN logo
TEN

Eagles vs Titans · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

PHI logo
PHI
PHI

23.62

-6.5 -120

o39.5 -105

-310

TEN logo
TEN
TEN

15.37

+6.5 +102

u40.0 -115

+280

Pittsburgh @ New England
Matchup Stats

Predicted Score

PIT logo
PIT
PIT

18.91 @ 23.48

NE
NE logo
NE

Steelers vs Patriots · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

PIT logo
PIT
PIT

18.91

+5.5 -109

o41.5 -108

+205

NE logo
NE
NE

23.48

-5.5 -105

u41.5 -107

-218

Top Projection Aaron Rodgers o207.5 Passing Yards (-111)
o203.5-115
Minnesota @ Chicago
Matchup Stats

Predicted Score

MIN logo
MIN
MIN

18.68 @ 23.59

CHI
CHI logo
CHI

Vikings vs Bears · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

MIN logo
MIN
MIN

18.68

+5.5 -109

o48.0 -110

+205

CHI logo
CHI
CHI

23.59

-5.5 -108

u48.5 -112

-235

Carolina @ Atlanta
Matchup Stats

Predicted Score

CAR logo
CAR
CAR

21.38 @ 23.03

ATL
ATL logo
ATL

Panthers vs Falcons · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

CAR logo
CAR
CAR

21.38

-2.5 -109

o43.5 -110

-134

ATL logo
ATL
ATL

23.03

+2.5 -105

u44.0 -113

+121

Top Projection Kyle Pitts Sr. o30.5 Receiving Yards (-140)
o30.5-140
Green Bay @ N.Y. Jets
Matchup Stats

Predicted Score

GB logo
GB
GB

25.46 @ 19.42

NYJ
NYJ logo
NYJ

Packers vs Jets · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

GB logo
GB
GB

25.46

-3.5 -105

o44.5 -110

-185

NYJ logo
NYJ
NYJ

19.42

+3.5 -107

u44.5 -105

+170

Top Projection MarShawn Lloyd o45.5 Rushing Yards (-125)
o45.5-125
New Orleans @ Baltimore
Matchup Stats

Predicted Score

NO logo
NO
NO

20.49 @ 25.82

BAL
BAL logo
BAL

Saints vs Ravens · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

NO logo
NO
NO

20.49

+8.5 -109

o46.5 -115

+330

BAL logo
BAL
BAL

25.82

-8.5 +100

u47.5 -112

-400

Cincinnati @ Houston
Matchup Stats

Predicted Score

CIN logo
CIN
CIN

25.02 @ 26.04

HOU
HOU logo
HOU

Bengals vs Texans · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

CIN logo
CIN
CIN

25.02

+2.5 +100

o46.5 -110

+134

HOU logo
HOU
HOU

26.04

-2.5 -118

u46.5 -105

-145

Cleveland @ Tampa Bay
Matchup Stats

Predicted Score

CLE logo
CLE
CLE

15.56 @ 23.33

TB
TB logo
TB

Browns vs Buccaneers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

CLE logo
CLE
CLE

15.56

+8.5 -109

o41.0 -107

+350

TB logo
TB
TB

23.33

-8.5 -105

u41.5 -110

-395

Jacksonville @ Denver
Matchup Stats

Predicted Score

JAC logo
JAC
JAC

20.90 @ 24.61

DEN
DEN logo
DEN

Jaguars vs Broncos · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

JAC logo
JAC
JAC

20.90

+3.5 -135

o44.5 -118

+130

DEN logo
DEN
DEN

24.61

-3.5 -115

u45.5 -110

-148

Las Vegas @ L.A. Chargers
Matchup Stats

Predicted Score

LV logo
LV
LV

19.29 @ 24.49

LAC
LAC logo
LAC

Raiders vs Chargers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

LV logo
LV
LV

19.29

+6.5 -105

o43.5 -105

+250

LAC logo
LAC
LAC

24.49

-6.5 -110

u43.5 -107

-290

Seattle @ Arizona
Matchup Stats

Predicted Score

SEA logo
SEA
SEA

21.88 @ 21.15

ARI
ARI logo
ARI

Seahawks vs Cardinals · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

SEA logo
SEA
SEA

21.88

-3.5 -115

o40.5 -115

-200

ARI logo
ARI
ARI

21.15

+3.5 -105

u41.5 -115

+176

Top Projection Jacoby Brissett u5.5 Rushing Yards (-115)
u5.5-115
Miami @ San Francisco
Matchup Stats

Predicted Score

MIA logo
MIA
MIA

17.95 @ 27.39

SF
SF logo
SF

Dolphins vs 49ers · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

MIA logo
MIA
MIA

17.95

+13.5 -110

o45.5 -108

+700

SF logo
SF
SF

27.39

-13.5 -105

u46.5 -115

-900

Top Projection Greg Dulcich o20.5 Receiving Yards (-140)
o20.5-140
Washington @ Dallas
Matchup Stats

Predicted Score

WAS logo
WAS
WAS

24.50 @ 29.57

DAL
DAL logo
DAL

Commanders vs Cowboys · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

WAS logo
WAS
WAS

24.50

+4.5 -110

o49.5 -129

+180

DAL logo
DAL
DAL

29.57

-4.5 -103

u50.5 -108

-200

Indianapolis @ Kansas City
Matchup Stats

Predicted Score

IND logo
IND
IND

20.53 @ 24.37

KC
KC logo
KC

Colts vs Chiefs · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

IND logo
IND
IND

20.53

+6.5 +100

o46.5 -108

+265

KC logo
KC
KC

24.37

-6.5 -115

u47.0 -114

-285

Top Projection Patrick Mahomes u15.5 Rushing Yards (-115)
u15.5-115
N.Y. Giants @ L.A. Rams
Matchup Stats

Predicted Score

NYG logo
NYG
NYG

19.99 @ 30.26

LA
LA logo
LA

Giants vs Rams · Prediction & Game Odds

Team

Predicted Score

Spread

Total

ML

NYG logo
NYG
NYG

19.99

+7.5 -115

o47.5 -115

+295

LA logo
LA
LA

30.26

-7.5 +102

u48.5 -110

-345

Top Projection Jaxson Dart u29.5 Rushing Yards (-114)
u30.5-118
Detroit Lions image thumbnail DET @ Buffalo Bills image thumbnail BUF Thu, Sep 17 • 8:15 PM ET
Spread
Detroit Lions image thumbnail DET +4.5 (-102)
Best Odds
Pick made: 6 hours ago
Jon Metler logo
Jon Metler
Betting Analyst

Give me the Lions catching 4.5 points, as I make them closer to a 3-point underdog against the Buffalo Bills on Thursday Night Football. A lot will be made about Detroit's secondary, but it's not like Buffalo's secondary was slowing down the Texans' offense in Week 1. Jared Goff needs a clean pocket to be effective, and I think Penei Sewell is the key to this matchup. Sewell can completely neutralize Bradley Chubb one-on-one, allowing the Lions to shift their protection toward Ed Oliver and Greg Rousseau. That should give Detroit a better chance to keep Goff's jersey clean without compromising its route numbers.

Anytime Touchdown
James Cook III logo James Cook III Score a Touchdown (Yes: -131)
Best Odds
Pick made: 13 hours ago
Jason Logan logo
Jason Logan
Senior Betting Analyst

All in all, it was a quiet opener for Cook in what turned into a shootout in Houston. He carried the ball only 13 times and was targeted on four passes for three receptions. That lack of involvement was addressed by offensive coordinator Pete Carmichael. “I think any time you can get ball in James Cook’s hands, it’s a great thing,” Carmichael told the media. “The opportunities to get the ball in his hands will be important, going forward.” OK, Pete. We’re trusting you here. Touchdown projections give Cook between a 60% and 77% shot at finding paydirt at new Highmark.

View 18 Picks
Philadelphia Eagles image thumbnail PHI @ Tennessee Titans image thumbnail TEN Sun, Sep 20 • 1:00 PM ET
Receiving Yards
Wan'Dale Robinson logo
Wan'Dale Robinson o35.5 Receiving Yards (-115)
Projection 45.54 (Over)
Best Odds
Pick made: 5 hours ago
EV Model Rating
Star rating: 5 out of 5
An extreme throwing game script is implied by the Titans being a giant -7-point underdog in this game.. The predictive model expects the Tennessee Titans as the 10th-most pass-oriented offense among all teams this week with a 59.7% pass rate, accounting for their underlying propensities and matchup dynamics.. Our trusted projections expect the Titans to be the 6th-quickest paced defense in the league (adjusted for context) at the present time, with opposing offenses averaging 28.31 seconds per play.. In this contest, Wan'Dale Robinson is projected by our trusted projection set to position himself in the 89th percentile among WRs with 7.6 targets.. Wan'Dale Robinson has notched a massive 74.0 air yards per game last year: 84th percentile when it comes to WRs.
Rushing Yards
Tony Pollard logo
Tony Pollard o45.5 Rushing Yards (-115)
Projection 60.61 (Over)
Best Odds
Pick made: 9 hours ago
EV Model Rating
Star rating: 5 out of 5
Our trusted projections expect the Titans to be the 6th-quickest paced defense in the league (adjusted for context) at the present time, with opposing offenses averaging 28.31 seconds per play.. In this week's contest, Tony Pollard is expected by the model to secure a spot in the 87th percentile among running backs with 15.8 rush attempts.. Tony Pollard has been given 65.3% of his team's run game usage last year, putting him in the 96th percentile among RBs.. Tony Pollard has grinded out 51.0 adjusted yards per game on the ground last year, one of the largest figures in football when it comes to RBs (86th percentile).. Tony Pollard ranks as one of the leading running backs in the league at grinding out extra rushing yardage, averaging an excellent 3.21 yards-after-contact last year while checking in at the 75th percentile.
View 7 Picks
Pittsburgh Steelers image thumbnail PIT @ New England Patriots image thumbnail NE Sun, Sep 20 • 1:00 PM ET
Total
Pittsburgh Steelers image thumbnail New England Patriots image thumbnail u42.5 (-110)
Best Odds
Pick made: yesterday
Neil Parker logo
Neil Parker
Betting Analyst

The Steelers are built for Unders, and the Patriots lack game-breaking talent on offense with wide receiver A.J. Brown (ankle) out and running back TreVeyon Henderson (ankle) still nursing an injury. Pittsburgh quarterback Aaron Rodgers completed just 60% of his passes for a pedestrian 5.6 yards per attempt in Week 1, and New England QB Drake Maye’s 5.4 YPA and 6.5 aDoT in the season opener don’t jump off the page, either. The Steelers also allowed the fourth-lowest EPA per play, with the Pats surrendering the seventh lowest ahead of Monday Night Football, so we’re landing a fair number on this Under given the lack of offensive explosiveness going against this pair of stout stop units.

Receiving Yards
Hunter Henry logo
Hunter Henry o30.5 Receiving Yards (-140)
Projection 45.8 (Over)
Best Odds
Pick made: 4 hours ago
EV Model Rating
Star rating: 5 out of 5
The Steelers defense has been something of pass funnel last year, inducing opposing quarterbacks to attempt the 5th-most passes in the NFL (35.8 per game) last year.. In this week's game, Hunter Henry is predicted by the predictive model to rank in the 78th percentile among TEs with 4.8 targets.. Hunter Henry has been a big part of his team's passing attack, garnering a Target Share of 17.6% last year, which puts him in the 88th percentile among tight ends.. Hunter Henry has put up a whopping 40.0 air yards per game last year: 90th percentile when it comes to tight ends.. When it comes to pass-blocking (and the strong impact it has on all pass attack metrics), the O-line of the New England Patriots grades out as the 5th-best in football last year.
View 10 Picks
Minnesota Vikings image thumbnail MIN @ Chicago Bears image thumbnail CHI Sun, Sep 20 • 1:00 PM ET
Spread
Chicago Bears image thumbnail CHI -5.5 (-110)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

While Wentz was serviceable, I see more than two points separating him and Murry in terms of value to the spread. That’s especially true if the Bears can break away on the scoreboard and force Wentz to carry the load. Minnesota’s defense is dangerous but gave up a ton of yards to the Packers. If we take the Cheeseheads’ fourth-quarter collapse out of the equation, the Vikes stop unit was 21st in EPA allowed per play in the first three quarters. Murray’s chances of clearing concussion protocols seems slim when you look at his reaction to the hit. Once he’s officially ruled out, this spread jumps to Bears -6 or higher. Give me Chicago below the key number now.

Passing Yards
Caleb Williams logo
Caleb Williams u228.5 Passing Yards (-115)
Projection 211.7 (Under)
Best Odds
Pick made: 14 minutes ago
EV Model Rating
Star rating: 5 out of 5
The Bears are a 5.5-point favorite in this game, likely leading to a running game script.. The projections expect the Chicago Bears as the 5th-least pass-oriented offense among all teams this week with a 52.3% pass rate, based on their underlying tendencies and matchup dynamics.. Opposing offenses teams have been disinclined to lean on the pass against the Vikings, averaging the fewest attempts in football (a measly 27.4 per game) last year.. Last year, the imposing Minnesota Vikings defense has given up a measly 162.0 adjusted yards per game through the air to opposing teams: the best in the NFL.
View 11 Picks
Carolina Panthers image thumbnail CAR @ Atlanta Falcons image thumbnail ATL Sun, Sep 20 • 1:00 PM ET
Total
Carolina Panthers image thumbnail Atlanta Falcons image thumbnail o43.5 (-111)
Best Odds
Pick made: yesterday
Shawn Krest logo
Shawn Krest
Betting Analyst

Stay Over up to 45.5. The Panthers answered all questions about their offense in the opener, and the Carolina defense didn't show it was capable of stopping anyone. The Panthers have set scoring records for the preseason Hall of Fame Game and the NFL Week One opener. 

Spread
Atlanta Falcons image thumbnail ATL +1.5 (-111)
Best Odds
Pick made: yesterday
Shawn Krest logo
Shawn Krest
Betting Analyst

Stick with Atlanta up until -1.5. Falcons running back Bijan Robinson carrying the ball against a Panthers' defense that gave up a half dozen rushing touchdowns in the opener is a bad matchup for Carolina. Atlanta's offense could also get a boost if Tua Tagovailoa can return from injury.

View 11 Picks
Green Bay Packers image thumbnail GB @ New York Jets image thumbnail NYJ Sun, Sep 20 • 1:00 PM ET
Total
Green Bay Packers image thumbnail New York Jets image thumbnail u44.5 (-111)
Best Odds
Pick made: yesterday
Ed Scimia logo
Ed Scimia
Betting Analyst

The New York Jets averaged just 17.6 ppg last year and while Geno Smith is an upgrade at quarterback, I'm unconvinced that he's going to improve the situation all that much at age 35. Meanwhile, the Jets defense will get pressure on a one-dimensional Green Bay Packers offense that totaled just 66 yards on the ground against the Vikings. I'm backing the Under down to 42.5 points.

Spread
New York Jets image thumbnail NYJ +3.5 (-111)
Best Odds
Pick made: yesterday
Ed Scimia logo
Ed Scimia
Betting Analyst

There's no denying it: the New York Jets looked downright competent in Week 1. Breece Hall ran for 102 yards, Geno Smith was efficient in the passing game, and the defense held the Tennessee Titans to -0.28 EPA per pass. At home, I like New York to cover against the Green Bay Packers as long as the spread stays above a field goal.

View 8 Picks
New Orleans Saints image thumbnail NO @ Baltimore Ravens image thumbnail BAL Sun, Sep 20 • 1:00 PM ET
Total
New Orleans Saints image thumbnail Baltimore Ravens image thumbnail u47.5 (-110)
Best Odds
Pick made: yesterday
Jason Logan logo
Jason Logan
Senior Betting Analyst

The New Orleans Saints looked dead in the water for the first 30 minutes of the 2026 season. They were 27th in EPA per play in the first half versus Detroit on Sunday before the Lions took their foot off the gas and found themselves in an overtime squeaker. New Orleans’ output looks better than it was, scoring six points in the extra frame (before missing the 2-point convert). The Baltimore Ravens hung 41 points on Indianapolis in Week 1 but took a hit in the receiving corps, losing Zay Flowers and Ja'Kobi Lane to injury. This group was already thin and could have Baltimore’s offense short and simple in Week 2. The Ravens ran at the second highest rate in the opener (58%), mainly due to protecting a big lead in the second half. But they could be forced into similar handoffs with the passing game missing pieces.

Receiving Yards
Chris Olave logo
Chris Olave o65.5 Receiving Yards (-135)
Projection 75.18 (Over)
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 5 out of 5
The Saints are an enormous 8.5-point underdog in this week's contest, which points towards an extreme passing game script.. Based on their underlying tendencies and matchup dynamics, the leading projections forecast the New Orleans Saints to pass on 61.2% of their chances: the 4th-greatest clip on the slate this week.. The New Orleans Saints have run the 3rd-most plays in the NFL since the start of last season, totaling a colossal 60.4 plays per game.. The Baltimore Ravens defense has been something of pass funnel last year, inducing opposing teams to attempt the 2nd-most passes in the NFL (36.2 per game) last year.. In this week's contest, Chris Olave is predicted by the projections to slot into the 97th percentile among WRs with 10.1 targets.
View 6 Picks
Cincinnati Bengals image thumbnail CIN @ Houston Texans image thumbnail HOU Sun, Sep 20 • 1:00 PM ET
Spread
Houston Texans image thumbnail HOU -2.5 (-110)
Best Odds
Pick made: 2 days ago
Jason Logan logo
Jason Logan
Senior Betting Analyst

The Bengals got four takeaways and still had to sweat out the Bucs in Week 1. Houston's defense bounces back and that offense is improved and always strong at home. The Texans were 9 for 18 on 3rd/4th down conversions and went 4/5 for TDs in the red zone. Cincy finished 2/5 in RZ and needed a defensive score and four FGM (two 50+ yarders) to get to 33 points, despite those extra possesions.

Passing Yards
C.J. Stroud logo
C.J. Stroud o235.5 Passing Yards (-115)
Projection 261.74 (Over)
Best Odds
Pick made: 32 seconds ago
EV Model Rating
Star rating: 5 out of 5
The predictive model expects the Texans to be the 7th-most pass-focused team in football (adjusted for context) at the moment with a 61.9% pass rate.. Given their underlying propensities and game dynamics, the Houston Texans are predicted by our trusted projection set to run 65.8 offensive plays in this contest: the 6th-most among all teams this week.. The most plays in the NFL have been run by the Texans since the start of last season (a monstrous 60.8 per game on average).. The pass attacks of both teams (in terms of both volume and effectiveness) figure to benefit from the still "weather" conditions (i.e. zero wind) inside this dome, while run volume may drop.. The Cincinnati Bengals pass defense has displayed poor efficiency last year, allowing 8.63 adjusted yards-per-target: the 4th-most in the NFL.
View 11 Picks
Cleveland Browns image thumbnail CLE @ Tampa Bay Buccaneers image thumbnail TB Sun, Sep 20 • 1:00 PM ET
Anytime Touchdown
Bucky Irving logo
Bucky Irving Score a Touchdown (Yes: -110)
Projection 0.72 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
The Buccaneers rank as the 5th-most pass-focused team in football near the end zone (in a neutral context) this year with a 77.8% red zone pass rate.
Receiving Yards
Emeka Egbuka logo
Emeka Egbuka o45.5 Receiving Yards (-135)
Projection 55.08 (Over)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
The Cleveland Browns pass defense has struggled when opposing wideouts have gotten into space, allowing an average of 0.00 yards-after-the-catch last year: the most in football.
View 7 Picks
Jacksonville Jaguars image thumbnail JAC @ Denver Broncos image thumbnail DEN Sun, Sep 20 • 4:05 PM ET
Receiving Yards
Evan Engram logo
Evan Engram o20.5 Receiving Yards (-125)
Projection 35.15 (Over)
Best Odds
Pick made: 32 seconds ago
EV Model Rating
Star rating: 5 out of 5
Given their underlying play style and matchup dynamics, the model projects the Broncos to pass on 60.1% of their plays: the 8th-highest rate on the slate this week.. The leading projections forecast this game to have the most plays run out of all the games this week at 131.9 plays, given the play styles of each team and game dynamics.. The Broncos have run the 8th-most plays in football since the start of last season, totaling a staggering 58.7 plays per game.. The Jacksonville Jaguars defense has been a prominent pass funnel last year, leading opposing quarterbacks to attempt the most passes in the NFL (37.5 per game) last year.. The projections expect Evan Engram to accrue 5.5 targets in this game, on balance, placing him in the 86th percentile among TEs.
Receiving Yards
Brenton Strange logo
Brenton Strange o30.5 Receiving Yards (-115)
Projection 36.48 (Over)
Best Odds
Pick made: 32 seconds ago
EV Model Rating
Star rating: 5 out of 5
The model projects the Jacksonville Jaguars as the 8th-most pass-heavy offense among all teams this week with a 60.1% pass rate, based on their underlying propensities and matchup dynamics.. Given the game dynamics and the underlying approaches of each team, this game is forecasted by the model to see 131.9 offensive plays called: the highest number among all games this week.. The Jaguars have run the 9th-most plays in football since the start of last season, totaling a massive 58.4 plays per game.. Opposing offenses have averaged 34.4 pass attempts per game versus the Denver Broncos defense last year: 6th-most in the league.. Brenton Strange has run a route on 73.9% of his offense's passing plays last year, putting him in the 88th percentile when it comes to TEs.
View 10 Picks
Las Vegas Raiders image thumbnail LV @ Los Angeles Chargers image thumbnail LAC Sun, Sep 20 • 4:05 PM ET
Rushing Yards
Omarion Hampton logo
Omarion Hampton o60.5 Rushing Yards (-125)
Projection 79.14 (Over)
Best Odds
Pick made: 24 minutes ago
EV Model Rating
Star rating: 5 out of 5
This game's line implies an extreme rushing game script for the Chargers, who are a heavy favorite by 7 points.. The predictive model expects the Los Angeles Chargers as the 6th-most run-centric team among all teams this week with a 47.6% run rate, based on their underlying strategic approach and matchup dynamics.. The 7th-most plays in the NFL have been run by the Los Angeles Chargers since the start of last season (a colossal 59.5 per game on average).
Passing Yards
Kirk Cousins logo
Kirk Cousins o185.5 Passing Yards (-120)
Projection 209.74 (Over)
Best Odds
Pick made: 2 hours ago
EV Model Rating
Star rating: 5 out of 5
An extreme throwing game script is suggested by the Raiders being a huge -7-point underdog in this game.. The leading projections forecast the Las Vegas Raiders to be the 5th-most pass-centric offense among all teams this week with a 60.4% pass rate, given their underlying traits and matchup dynamics.. Calm weather conditions (like the 1-mph wind being forecasted in this game) usually prompt increased passing effectiveness, higher touchdown potential, higher pass volume, and lower rush volume.. Last year, the deficient Los Angeles Chargers defense has given up the most yards-after-the-catch in the league to the opposing side: a staggering 0.00 YAC.
View 5 Picks
Seattle Seahawks image thumbnail SEA @ Arizona Cardinals image thumbnail ARI Sun, Sep 20 • 4:25 PM ET
Passing Yards
Jacoby Brissett logo
Jacoby Brissett o215.5 Passing Yards (-110)
Projection 239.9 (Over)
Best Odds
Pick made: 5 hours ago
EV Model Rating
Star rating: 5 out of 5
A passing game script is indicated by the Cardinals being a -4-point underdog in this week's game.. The predictive model expects the Arizona Cardinals as the 3rd-most pass-focused team among all teams this week with a 62.8% pass rate, based on their underlying strategic approach and matchup dynamics.. The 4th-largest volume of plays in the league have been run by the Arizona Cardinals since the start of last season (a staggering 60.0 per game on average).. The Seattle Seahawks defense has been a prominent pass funnel last year, leading opposing quarterbacks to attempt the 4th-most passes in football (36.1 per game) last year.. Jacoby Brissett grades out as one of the best quarterbacks in the league last year, averaging a stellar 220.0 adjusted yards per game while ranking in the 90th percentile.
Receiving Yards
Trey McBride logo
Trey McBride o55.5 Receiving Yards (-125)
Projection 66.71 (Over)
Best Odds
Pick made: 5 hours ago
EV Model Rating
Star rating: 5 out of 5
A passing game script is indicated by the Cardinals being a -4-point underdog in this week's game.. The predictive model expects the Arizona Cardinals as the 3rd-most pass-focused team among all teams this week with a 62.8% pass rate, based on their underlying strategic approach and matchup dynamics.. The 4th-largest volume of plays in the league have been run by the Arizona Cardinals since the start of last season (a staggering 60.0 per game on average).. This game will be played in a dome—which means no wind, increased pass volume, increased TD potential, and better passing effectiveness.. The Seattle Seahawks defense has been a prominent pass funnel last year, leading opposing quarterbacks to attempt the 4th-most passes in football (36.1 per game) last year.
View 5 Picks
Miami Dolphins image thumbnail MIA @ San Francisco 49ers image thumbnail SF Sun, Sep 20 • 4:25 PM ET
Rushing Yards
De'Von Achane logo
De'Von Achane o45.5 Rushing Yards (-135)
Projection 70.96 (Over)
Best Odds
Pick made: 4 hours ago
EV Model Rating
Star rating: 5 out of 5
The projections expect the Dolphins to be the 5th-most run-heavy team in the league (adjusted for context) at the present time with a 41.9% run rate.. Our trusted projections expect De'Von Achane to accrue 16.2 rush attempts this week, on balance, placing him in the 88th percentile among RBs.. De'Von Achane has received 62.9% of his team's rushing play calls last year, ranking him in the 93rd percentile among RBs.. De'Von Achane has grinded out 68.0 adjusted rushing yards per game last year, one of the biggest figures in the league among running backs (96th percentile).. With an impressive tally of 5.16 adjusted yards per carry (90th percentile), De'Von Achane stands among the best pure rushers in the NFL last year.
Receiving Yards
Mike Evans logo
Mike Evans o44.5 Receiving Yards (-115)
Projection 55.38 (Over)
Best Odds
Pick made: 6 hours ago
EV Model Rating
Star rating: 5 out of 5
The 10th-largest volume of plays in the NFL have been called by the San Francisco 49ers since the start of last season (a colossal 58.3 per game on average).. Our trusted projections expect Mike Evans to accumulate 6.5 targets in this contest, on balance, ranking him in the 77th percentile among WRs.. When it comes to air yards, Mike Evans ranks in the lofty 97th percentile among wide receivers last year, accruing a monstrous 106.0 per game.. Mike Evans's 59.6 WOPR (Weighted Opportunity Rating—an advanced metric that calculates high-value offensive usage) ranks among the league leaders: 90th percentile for wide receivers.. With an exceptional 39.0 adjusted receiving yards per game (75th percentile) last year, Mike Evans has been as one of the best wide receivers in the NFL in the league.
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Washington Commanders image thumbnail WAS @ Dallas Cowboys image thumbnail DAL Sun, Sep 20 • 4:25 PM ET
Receiving Yards
Terry McLaurin logo
Terry McLaurin o51.5 Receiving Yards (-114)
Projection 66.32 (Over)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 5 out of 5
This game's spread suggests a passing game script for the Commanders, who are -3.5-point underdogs.. The leading projections forecast this game to have the 3rd-largest volume of plays run out of all the games this week at 130.9 plays, based on the traits of each team and game dynamics.. The pass games of both teams (in terms of both volume and efficiency) stand to benefit from the still "weather" conditions (i.e. no wind) inside this dome, while ground volume may drop-off.. Opposing offenses have averaged 33.6 pass attempts per game versus the Cowboys defense last year: 9th-most in the NFL.. The projections expect Terry McLaurin to garner 7.6 targets in this week's game, on average, putting him in the 89th percentile when it comes to WRs.
Receiving Yards
Jake Ferguson logo
Jake Ferguson o27.5 Receiving Yards (-115)
Projection 39.6 (Over)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 5 out of 5
The leading projections forecast the Cowboys to be the 10th-most pass-heavy offense in the NFL (in a neutral context) at the moment with a 61.6% pass rate.. The model projects this game to see the 3rd-highest number of plays run out of all the games this week at 130.9 plays, accounting for the tendencies of each team and game dynamics.. The 5th-highest number of plays in the league have been run by the Cowboys since the start of last season (a massive 59.9 per game on average).. The pass attacks of both teams (in terms of both volume and efficiency) figure to benefit from the still "weather" conditions (meaning no wind) inside this dome, while ground volume may drop-off.. Last year, the feeble Commanders defense has allowed the most adjusted yards-per-target in the NFL to opposing tight ends: a massive 10.17 yards.
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Indianapolis Colts image thumbnail IND @ Kansas City Chiefs image thumbnail KC Sun, Sep 20 • 8:20 PM ET
Anytime Touchdown
Kenneth Walker logo
Kenneth Walker Score a Touchdown (Yes: -179)
Projection 0.92 (Yes)
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
The projections expect the Kansas City Chiefs to run the 3rd-most plays on offense on the slate this week with 66.0 plays, given their underlying propensities and game dynamics.. The Indianapolis Colts defense has been something of pass funnel last year, tempting opposing offenses to attempt the 2nd-most passes in the NFL (36.2 per game) last year.. The predictive model expects Kenneth Walker III to be a more important option in his team's pass game near the goal line this week (12.8% projected Red Zone Target Share) than he has been since the start of last season (4.5% in games he has played).. In regards to pocket protection (and the strong effect it has on all passing attack stats), the O-line of the Kansas City Chiefs ranks as the 8th-best in football last year.. Kenneth Walker III is positioned as one of the best possession receivers in football among running backs, hauling in an exceptional 91.5% of balls thrown his way (adjusted for context) last year, grading out in the 90th percentile.
Receiving Yards
Josh Downs logo
Josh Downs o34.5 Receiving Yards (-115)
Projection 52.87 (Over)
Best Odds
Pick made: 4 hours ago
EV Model Rating
Star rating: 5 out of 5
The Colts are a 6.5-point underdog in this week's game, likely creating a passing game script.. Based on their underlying propensities and matchup dynamics, the predictive model expects the Indianapolis Colts to pass on 0.0% of their opportunities: the lowest frequency among all teams this week.. Based on the game dynamics and the underlying play styles of each team, this game is predicted by the predictive model to see 130.6 total plays called: the 4th-highest number among all games this week.. In this week's contest, Josh Downs is anticipated by the projection model to position himself in the 89th percentile among wideouts with 7.6 targets.. Last year, the anemic Kansas City Chiefs pass defense has been gouged for a staggering 67.4% Adjusted Completion Rate to opposing wide receivers: the 6th-highest rate in football.
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New York Giants image thumbnail NYG @ Los Angeles Rams image thumbnail LA Mon, Sep 21 • 8:15 PM ET
Game Prop
Los Angeles Rams image thumbnail o27.5 Team Total (-120)
Best Odds
Pick made: 19 hours ago
Jason Logan logo
Jason Logan
Senior Betting Analyst

Sean McVay is an excellent game planner with added time he'll work out the kinks on this offense. Matthew Stafford couldn’t get going against the 49ers but faces a softer stop unit from the Giants. New York’s defense looked much better than it truly was in Week 1, due to the offense grinding out gains and chewing up TOP. The Cowboys offense only had two second half possessions and while it was limited in action, Dallas ranked out well in terms of advanced metrics like EPA per play DVOA. This is a fast track indoor at SoFi Stadium and it doesn’t seem likely that L.A.’s offense gets bottled up for a second straight game. 

Rushing Yards
Cam Skattebo logo
Cam Skattebo o49.5 Rushing Yards (-114)
Projection 57.11 (Over)
Best Odds
Pick made: 4 minutes ago
EV Model Rating
Star rating: 5 out of 5
At the moment, the 7th-most run-oriented team in the league (41.0% context-neutralized) according to our trusted projection set is the New York Giants.. The 6th-highest number of plays in the league have been called by the Giants since the start of last season (a staggering 59.7 per game on average).
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For every matchup in an NFL season, our NFL computer produces selections for a variety of different betting angles. Our computer picks are based on a proprietary algorithm that values each team in the current week to produce moneyline, spread, and point total selections.

The table above, below the game picks, tracks our NFL computer's results over the last 100 games, outlining the record and profit for selections, based on $100 unit size. We track the profit based on both opening and closing lines for every matchup.

How to Use NFL Computer Picks

The easiest way to utilize our computer picks is to simply follow our selections for every matchup, what you'd call ailing the computer." But there are other ways to utilize our NFL computer picks, as well.

You can use our NFL computer as a jumping-off point to do more research into specific lines, cross-referencing with expert picks, which can be found above the selections for some matchups, recent NFL betting trends, and more.

As well, you can gauge the confidence of the matchup. The larger the projected score, the more confident the computer is in a specific pick.

Or, if you want to implement a system, betting only on underdogs, for example, you can look for matchups in which our computer likes the underdog to inform which picks you're going to hone in on for a given week.

We have these computer picks for every sport you're looking to wager on, as well:

Free Computer Picks by Odds Shark

Moneyline

NFL moneyline picks are the simplest way to get in on the NFL action. All you have to do is simply bet on which team you think will win the game.

For moneyline picks, the favorite is represented with a minus sign (-) in front of the odds, while the underdog has a plus (+). However, you don't get the same profit for picking an underdog compared to a favorite. If the favored team is -120, a $100 bet on them would pay out $80 in profit and $180 total, if they win the game. The underdog winning at +150 would pay out a $150 profit, $250 total.

We have a complete breakdown of how to read NFL moneyline odds for these NFL computer picks.

Spread

While moneyline picks are the simplest, picking NFL games against the spread is probably the most common wager for regular NFL bettors.

To bet an NFL spread, you wager on whether a team will win by a certain number of points or more or if they'll lose by fewer points than the spread. For example, if the spread is -6.5 for the New England Patriots, you would win the bet if they win the game by 7 points or more. Or if a team is +6.5, you're betting on if they'll win outright or lose by fewer than 6.5 points.

There is a correlation between moneyline odds and the spread, as books set these lines based on the same information.

You can read more about NFL spreads here.

Totals (Over/Under)

If you aren’t entirely sold on which NFL team will win or cover in an NFL game, you can still use our NFL computer picks to bet on the point total.

As opposed to taking a side, in total or Over/Under betting, you wager on whether both NFL teams will combine for a final score of more than (Over) or less than (Under) the total number of points set by oddsmakers.

The computer picks, and your handicapping of totals is more about how you think both teams will score points, not which team has the edge to win.

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