Get free expert and computer MLB picks for every game on April 22, 2026. With over 25 years of betting experience, our analysts and predictive models help you find the best value.
SD
@
COL
Tue, Apr 21 • 8:40 PM ET
Brenton Doyle o0.5 Total Home Runs (+700)
Brenton Doyle might hit near the bottom of the Colorado Rockies lineup, but his +700 home run price at home vs. Randy Vásquez is a great number that I’d play down to +600. Coors Field is always a strong backdrop, but it stands out even more on this slate and projects as the top hitting environment on Tuesday. The snow is gone, temperatures are up to 80 degrees, and the wind is blowing out to left field — all pointing to a favorable home run setup. Vásquez can allow solid contact and ranks among the worst pitchers in baseball in Blast Contact% through the first month. Doyle may only have one homer so far, but it came against Vásquez two weeks ago, and he also brings one of the fastest swings in the Colorado lineup.
TOR
@
LAA
Tue, Apr 21 • 9:38 PM ET
Vladimir Guerrero Jr. o0.5 Total Home Runs (+600)
Guerrero Jr. has been known to hit his homers in bunches, so I’ll bet on him getting another one tonight in Angel Stadium after going yard last night. Additionally, Vladdy does seem to torture sinker ballers. He has a 56.6% hard-hit rate against the pitch this season, while posting a .532 slug-rate against it in 2025.
Vladimir Guerrero Jr. o1.5 Total Bases (+110)
Vladimir Guerrero Jr. has been one of the most consistent hitters in baseball this season, batting .354, the second-highest average in the majors. Vladdy is also currently riding an 11-game hitting streak, averaging 2.54 bases per contest in that stretch.
CHW
@
AZ
Tue, Apr 21 • 9:40 PM ET
ATH
@
SEA
Tue, Apr 21 • 9:40 PM ET
LAD
@
SF
Tue, Apr 21 • 9:45 PM ET
LAD FirstFiveInnings -0.5 (-115)
The Dodgers have a clear early edge, leading MLB in runs scored in innings 1–5 on the road, while the Giants rank dead last at home. Los Angeles is also in better form, leading the league in OPS over the past week compared to San Francisco at 18th. Yoshinobu Yamamoto has been dominant, allowing just two earned runs in his last two starts and has owned Giants hitters, holding them to a combined .485 OPS in 79 at-bats, while Landen Roupp posted a 8.22 ERA in two appearances vs LA last season.
With temperatures in the mid-50s, it should be a pitcher-friendly environment. Yamamoto and Roupp have been two of the better starting pitchers in the league and should thrive.
There are two quality bullpens behind them as well — L.A. ranks seventh in SIERA in relief (3.45) while San Francisco (3.55) isn’t far behind at ninth and has all of its top options well-rested and at the ready.
Covers’ has more than 25 years of experience making smart MLB picks from the season’s first pitch to the World Series.
We find the best MLB odds and share our picks and baseball best bets for all the significant games of the baseball season right here on this page.
Our picks are researched and analyzed by experienced sports bettors looking for an edge to get the best value from their MLB betting.
Making smart MLB picks means looking beyond the favorites. Our free expert baseball picks will include a wide variety of bet types and markets.
Every day our baseball analysts look for quality baseball picks to share. You can expect well-researched picks on the money, run line, totals, player props, and much more.
Run lines are what other sports like football and basketball refer to as point spreads. Run lines even the odds between two teams, offering bettors as close to an even matchup as possible. Our analysts research vital stats, pitching matchups, injuries, and more to give you the best possible edge before making your MLB run line bets.
Covers’ analysts make MLB Over/Under picks throughout the baseball season. Betting on MLB Over/Unders means choosing whether you think the combined total runs scored in a game will be Over or Under a specific run total set by oddsmakers.
Betting on the MLB moneyline means picking which team will win a game outright. While less common than picking the run line or even a prop, our analysts will always look for high-value baseball moneyline picks if they feel it’s the best bet.
There’s always value in MLB props. Our team scours through game, team, and player props to try and find opportunity and value. From strikeouts to home runs, expect well-researched MLB prop picks from Covers.
Covers’ consensus MLB picks show you the odds and predictions that our vibrant community of bettors and players are making. Try our picks on with our free MLB contests for a chance at prizes and more.
If you’re ready to bet on MLB picks, you first need to find the right sportsbook. The best MLB betting sites offer secure banking, best odds, bonuses, and reliable customer service.
Covers’ staff of sports betting fans also offers a wide array of free picks for the NFL, NBA, NHL, NCAA basketball, and NCAA football.
Covers’ MLB picks release on game day. Some significant matchups like playoff games release in the days leading up to the game.
Covers provides free MLB picks covering many markets, including run lines, totals, moneylines, player props, and more.
Established in 1995,
All Picks
NFL
NCAAF
MLB
NBA
NCAAB
NHL
CFL
WNBA
Golf
World Cup
