MLB Picks

Get free expert and computer MLB picks for every game on April 21, 2026. With over 25 years of betting experience, our analysts and predictive models help you find the best value.

Cincinnati Reds logo CIN @ Tampa Bay Rays logo TB Tue, Apr 21 • 6:40 PM ET
10 Computer Picks
Total Bases
Sal Stewart logo
Sal Stewart o1.5 Total Bases (+125)
Projection 1.83
Best Odds
Pick made: 5 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Sal Stewart as the 17th-best batter in MLB when it comes to his batting average talent.. Sal Stewart is projected to hit 4th in the lineup in today's game.. The Tropicana Field roof is expected to be closed today, making the temperature in this contest 8° hotter than the average outdoor game of all games today — favorable for offense.. Hitting from the opposite that Steven Matz throws from, Sal Stewart will have an advantage in today's matchup.. Sal Stewart has an 86th percentile opposite-field rate on his flyballs (34.8%) and has the good fortune of hitting them towards MLB's 5th-shallowest RF fences in today's matchup.
Total Bases
Eugenio Suarez logo
Eugenio Suarez o1.5 Total Bases (+165)
Projection 1.54
Best Odds
Pick made: 5 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) ranks Eugenio Suarez as MLB's 20th-best home run hitter.. Eugenio Suarez is projected to hit 5th in the lineup in this matchup.. The Tropicana Field roof is expected to be closed today, making the temperature in this contest 8° hotter than the average outdoor game of all games today — favorable for offense.. Hitting from the opposite that Steven Matz throws from, Eugenio Suarez will have the upper hand in today's game.. Eugenio Suarez pulls a lot of his flyballs (39.4% — 96th percentile) and will have a big advantage hitting them towards baseball's 6th-shallowest LF fences in today's game.
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St. Louis Cardinals logo STL @ Miami Marlins logo MIA Tue, Apr 21 • 6:40 PM ET
8 Computer Picks
Total Hits
Kyle Stowers logo
Kyle Stowers u0.5 Total Hits (+180)
Projection 0.87
Best Odds
Pick made: 5 hours ago
EV Model Rating
Star rating: 3 out of 5
LoanDepot Park's elevation is near sea-level, one of the lowest in the league, which usually leads (as a rule of thumb) to worse offense.. Kyle Stowers pulls a lot of his flyballs (33.9% — 75th percentile) and will be challenged by baseball's 4th-deepest RF fences in today's game.. Out of all the teams today, the 5th-strongest infield defense is that of the St. Louis Cardinals.. Based on Statcast data, the leading projection system (THE BAT X)'s version of Expected Batting Average (.272) provides evidence that Kyle Stowers has had some very good luck since the start of last season with his .291 actual batting average.
Total Bases
Jordan Walker logo
Jordan Walker o1.5 Total Bases (+130)
Projection 1.78
Best Odds
Pick made: 20 minutes ago
EV Model Rating
Star rating: 3 out of 5
As it relates to his home run talent, Jordan Walker ranks in the 94th percentile according to the leading projection system (THE BAT X).. Jordan Walker is projected to bat 4th in the batting order in this matchup.. The LoanDepot Park roof figures to be closed today, making the temperature in this contest 8° hotter than the average outdoor game on the slate today — favorable for offense.. Jordan Walker has big-time HR ability (94th percentile) if he makes contact, but that's never a guarantee (28.3% K%). Today, however, opposing pitcher Chris Paddack struggles to strike batters out (18th percentile K%) — great news for Walker.. Jordan Walker hits a lot of his flyballs to center field (40.7% — 99th percentile) and is a great match for the park considering he'll be hitting towards MLB's 6th-shallowest CF fences today.
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Milwaukee Brewers logo MIL @ Detroit Tigers logo DET Tue, Apr 21 • 6:40 PM ET
2 Expert Picks 10 Computer Picks
Total
Milwaukee Brewers logo Detroit Tigers logo u8.5 (-107)
Best Odds
Pick made: 7 hours ago
Shawn Krest image
Shawn Krest
Betting Analyst

Keider Montero and Kyle Harrison have suppressed offenses effectively this season, and neither the Brewers nor the Tigers has lit scoreboards on fire yet in 2026.

Moneyline
Detroit Tigers logo DET (-110)
Best Odds
Pick made: 7 hours ago
Shawn Krest image
Shawn Krest
Betting Analyst

The Brewers have too many key players (Jackson Chourio, Andrew Vaughn, Christian Yelich) on the injured list to counter Keider Montero. And while Kyle Harrison has been effective on the mound, he missed his last start with an injury and may not be 100%.

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New York Yankees logo NYY @ Boston Red Sox logo BOS Tue, Apr 21 • 6:45 PM ET
3 Expert Picks 10 Computer Picks
Total
New York Yankees logo Boston Red Sox logo o8.5 (-105)
Best Odds
Pick made: 7 hours ago
Chris Hatfield image
Chris Hatfield
Betting Analyst

Luis Gil's struggles will open the door for success for the Boston Red Sox, but the New York Yankees should be able to score, too. Connelly Early's 13% barrel rate, paired with an average exit velocity that’s actually worse than Gil's, is going to give the Bronx Bombers clear paths to run-scoring opportunities. I’d play this to 9.5 with a fair amount of confidence.

Moneyline
Boston Red Sox logo BOS (-115)
Best Odds
Pick made: 7 hours ago
Chris Hatfield image
Chris Hatfield
Betting Analyst

Luis Gil has posted some of the worst underlying metrics in 2026 to begin the season for any starting pitcher. The command issues that tanked his 2025 persist, and a 6.40 xERA suggests a player who has been more bad than unlucky. Boston has enough power in the lineup to hurt him. They’ve done it before, and the sixth-best hard-hit rate in the league looms large here. At a pick-em price, the Red Sox have the better matchup.

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Atlanta Braves logo ATL @ Washington Nationals logo WAS Tue, Apr 21 • 6:45 PM ET
1 Expert Pick 10 Computer Picks
Moneyline
Atlanta Braves logo ATL (-138)
Best Odds
Pick made: 8 hours ago
Joe Osborne image
Joe Osborne
Senior Betting Analyst

While both starting pitchers are off to solid starts, the gap between these offenses is significant, and Atlanta’s bullpen has been dominant. The Braves are 4-0 in Reynaldo Lopez’s outings, with Lopez allowing one earned run or fewer three times. He draws a Nationals lineup ranked 28th in OPS vs RHP over the last two weeks. Meanwhile, Foster Griffin faces a tough task against an Atlanta team that's 6-1 when facing lefty starters. The Braves are second in the majors in runs per game on the road.

Total Hits
Jonah Heim logo
Jonah Heim u0.5 Total Hits (+151)
Projection 0.73
Best Odds
Pick made: 2 hours ago
EV Model Rating
Star rating: 3 out of 5
The leading projection system (THE BAT X) projects Jonah Heim in the 2nd percentile as it relates to his BABIP skill.. Jonah Heim is penciled in 8th in the batting order today.. When starting against a lefty hurler since the start of last season, Jonah Heim has been pulled from the game early 10% of the time.. The leading projection system (THE BAT) projects Nationals Park as the 4th-worst park in the game for right-handed batting average.. Nationals Park's altitude is near sea-level, one of the lowest in Major League Baseball, which tends to lead to lower offensive output.
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Minnesota Twins logo MIN @ New York Mets logo NYM Tue, Apr 21 • 7:10 PM ET
2 Expert Picks 10 Computer Picks
Total
Minnesota Twins logo New York Mets logo o7.5 (+103)
Best Odds
Pick made: 4 hours ago
Ed Scimia image
Ed Scimia
Betting Analyst

We all know that the Mets have been downright awful offensively, but they should find success tonight against Woods Richardson. 

The Twins starter has a career 4.35 ERA and 1.318 WHIP, isn’t a big strikeout pitcher, and gives up 1.3 homers per nine innings — all factors that a talented (if struggling) New York lineup can take advantage of.

Moneyline
New York Mets logo NYM (-157)
Best Odds
Pick made: 4 hours ago
Ed Scimia image
Ed Scimia
Betting Analyst

The Mets are catching a break in their first game back at Citi Field, as the Minnesota Twins are turning to starting pitcher Simeon Woods Richardson (0-3, 6.10 ERA) to take the mound after Mick Abel was placed on the injured list. Woods Richardson has had a rough start to the season, allowing 11 earned runs in nine innings over his past two starts.

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Philadelphia Phillies logo PHI @ Chicago Cubs logo CHC Tue, Apr 21 • 7:40 PM ET
2 Expert Picks 10 Computer Picks
Moneyline
Chicago Cubs logo CHC (-120)
Best Odds
Pick made: 7 hours ago
Todd Cordell image
Todd Cordell
Betting Analyst

The Phillies have scored two runs or fewer in five consecutive games and it’s difficult to envision things getting much better tonight. Philadelphia’s offense has been putrid against left-handed pitching, sporting a .260 wOBA (28th) and .549 OPS (29th). They now have to deal with Shota Imanaga, who has been one of the league’s best starters thus far. While I believe Jesus Luzardo to be much better than his counting stats indicate, this is a tough matchup to truly get back on track. The Cubs rank third in both wOBA and OPS against left-handed pitchers, and recorded 12 hits the last time they faced Luzardo.

Total
Philadelphia Phillies logo Chicago Cubs logo u8.5 (-105)
Best Odds
Pick made: 7 hours ago
Todd Cordell image
Todd Cordell
Betting Analyst

Jesus Luzardo is sporting a painful 7.94 ERA despite striking out six batters for every walk issued and allowing hard contact just 28.6% of the time. He has a 1.93 xFIP and 2.45 SIERA, excellent numbers that suggest much better days are ahead. Shota Imanaga has been lights out to date with sparkling metrics in many categories (2.45 ERA, 2.49 xFIP, 12.68 K/9). With strong bullpens behind these two starters – both teams rank Top-10 in xFIP this month – it’s difficult to envision either team putting up a ceiling performance at the plate.

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Baltimore Orioles logo BAL @ Kansas City Royals logo KC Tue, Apr 21 • 7:40 PM ET
2 Expert Picks 10 Computer Picks
Game Prop
Baltimore Orioles logo Kansas City Royals logo YRFI/NRFI (No: +102)
Best Odds
Pick made: 8 hours ago
Neil Parker image
Neil Parker
Betting Analyst

The Orioles and Royals respectively rank third and last in percentage of games scoring a run in the first inning, so even with the wind forecasted to be howling out at Kauffman Stadium, I’m expecting starters Shane Baz and Kris Bubic to post zeros in the opening frame. Baltimore hasn’t scored an opening-inning run on the road all season, and Kansas City is the lowest-scoring team in the opening frame for the year and second-lowest scoring team overall, too.

Total Bases
Jeremiah Jackson logo Jeremiah Jackson o1.5 Total Bases (+115)
Best Odds
Pick made: 17 hours ago
Eric Rosales image
Eric Rosales
Betting Analyst

Jeremiah Jackson has ripped lefty pitching this season, going 7-for-14 (.500) with a HR and five RBI, with a .714 slugging percentage.

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Pittsburgh Pirates logo PIT @ Texas Rangers logo TEX Tue, Apr 21 • 8:05 PM ET
10 Computer Picks
Total Bases
Oneil Cruz logo
Oneil Cruz o1.5 Total Bases (+135)
Projection 1.85
Best Odds
Pick made: 3 hours ago
EV Model Rating
Star rating: 4 out of 5
Oneil Cruz projects as the 11th-best home run hitter in the majors, per the leading projection system (THE BAT X).. Oneil Cruz is projected to bat 1st in the batting order in this matchup.. On average, the fence height at Globe Life Field is the 6th-lowest among all major league baseball stadiums.. The Globe Life Field roof figures to be closed today, making conditions in this contest 6° hotter than the average outdoor game of the day — favorable for offense.. Oneil Cruz will receive the benefit of the platoon advantage against Kumar Rocker in today's matchup... and moreover, Rocker has a large platoon split.
Total Bases
Corey Seager logo
Corey Seager o1.5 Total Bases (+135)
Projection 1.72
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 3 out of 5
Corey Seager projects as the 8th-best batter in the game, per the leading projection system (THE BAT X).. Corey Seager is penciled in 3rd in the batting order in this matchup.. On average, the fence height at Globe Life Field is the 6th-lowest among all major league baseball stadiums.. The Globe Life Field roof figures to be closed today, making conditions in this contest 6° hotter than the average outdoor game of the day — favorable for offense.. Corey Seager will have the benefit of the platoon advantage against Carmen Mlodzinski in today's game.
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San Diego Padres logo SD @ Colorado Rockies logo COL Tue, Apr 21 • 8:40 PM ET
1 Expert Pick 10 Computer Picks
Total Home Runs
Brenton Doyle logo Brenton Doyle o0.5 Total Home Runs (+700)
Best Odds
Pick made: 5 hours ago
Josh Inglis image
Josh Inglis
Betting Analyst

Brenton Doyle might hit near the bottom of the Colorado Rockies lineup, but his +700 home run price at home vs. Randy Vásquez is a great number that I’d play down to +600. Coors Field is always a strong backdrop, but it stands out even more on this slate and projects as the top hitting environment on Tuesday. The snow is gone, temperatures are up to 80 degrees, and the wind is blowing out to left field — all pointing to a favorable home run setup. Vásquez can allow solid contact and ranks among the worst pitchers in baseball in Blast Contact% through the first month. Doyle may only have one homer so far, but it came against Vásquez two weeks ago, and he also brings one of the fastest swings in the Colorado lineup.

Total Bases
Manny Machado logo
Manny Machado o1.5 Total Bases (+125)
Projection 2.14
Best Odds
Pick made: 4 hours ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects Manny Machado in the 90th percentile when assessing his overall offensive talent.. Manny Machado is projected to bat 4th in the batting order in this game.. The #1 venue in baseball for boosting offensive stats, via the leading projection system (THE BAT), is Coors Field.. Built 5197 feet above sea level, Coors Field has the highest elevation among all major league stadiums, which generally leads to higher offensive output.. The weather report calls for the most suitable hitting weather of all games on the slate today, as it relates to temperature and humidity.
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Toronto Blue Jays logo TOR @ Los Angeles Angels logo LAA Tue, Apr 21 • 9:38 PM ET
5 Expert Picks 10 Computer Picks
Total Home Runs
Vladimir Guerrero Jr. logo Vladimir Guerrero Jr. o0.5 Total Home Runs (+600)
Best Odds
Pick made: 5 hours ago
Mike DiStefano image
Mike DiStefano
Betting Analyst

Guerrero Jr. has been known to hit his homers in bunches, so I’ll bet on him getting another one tonight in Angel Stadium after going yard last night. Additionally, Vladdy does seem to torture sinker ballers. He has a 56.6% hard-hit rate against the pitch this season, while posting a .532 slug-rate against it in 2025.

 

Total Bases
Vladimir Guerrero Jr. logo Vladimir Guerrero Jr. o1.5 Total Bases (+110)
Best Odds
Pick made: 5 hours ago
Mike DiStefano image
Mike DiStefano
Betting Analyst

Vladimir Guerrero Jr. has been one of the most consistent hitters in baseball this season, batting .354, the second-highest average in the majors. Vladdy is also currently riding an 11-game hitting streak, averaging 2.54 bases per contest in that stretch. 

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Chicago White Sox logo CHW @ Arizona Diamondbacks logo AZ Tue, Apr 21 • 9:40 PM ET
10 Computer Picks
Total Bases
Munetaka Murakami logo
Munetaka Murakami u1.5 Total Bases (-165)
Projection 0.79
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
In Major League Baseball, the 10th-highest fence height (on average) are at Chase Field.. Today, Munetaka Murakami is at a disadvantage facing the league's 3rd-deepest CF center field fences given that he hits his flyballs towards center field at a 38.8% rate (91st percentile).. Playing on the road typically weakens hitter stats across the board due to the lack of home field advantage, which should be the case for Munetaka Murakami in today's game.. The leading projection system (THE BAT X) estimates Munetaka Murakami's true offensive talent to be a .343, providing some evidence that he has been very fortunate this year given the .041 discrepancy between that figure and his actual .384 wOBA.
Total Bases
Adrian Del Castillo logo
Adrian Del Castillo u1.5 Total Bases (-185)
Projection 0.79
Best Odds
Pick made: an hour ago
EV Model Rating
Star rating: 4 out of 5
In Major League Baseball, the 10th-highest fence height (on average) are at Chase Field.. Adrian Del Castillo hits a high percentage of his flyballs to center field (37.9% — 76th percentile) and will be challenged by the game's 3rd-deepest CF fences in today's matchup.. Typically, batters like Adrian Del Castillo who hit a lot of flyballs usually hit worse when facing pitchers who also induce a lot of flyballs such as Sean Burke.. In terms of his batting average, Adrian Del Castillo has experienced some positive variance since the start of last season. His .255 mark has been inflated compared to the leading projection system (THE BAT X)'s version of Statcast-based Expected Batting Average (xBA) at .201.. Adrian Del Castillo has shown bad plate discipline since the start of last season, checking in at the 13th percentile with a 6.05 K/BB rate.
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Athletics Athletics logo ATH @ Seattle Mariners logo SEA Tue, Apr 21 • 9:40 PM ET
10 Computer Picks
Total Bases
Nick Kurtz logo
Nick Kurtz o1.5 Total Bases (+145)
Projection 1.8
Best Odds
Pick made: 6 hours ago
EV Model Rating
Star rating: 4 out of 5
Nick Kurtz projects as the 9th-best home run hitter in the majors, via the leading projection system (THE BAT X).. Nick Kurtz is penciled in 1st on the lineup card in this game.. T-Mobile Park has the 9th-lowest fences in Major League Baseball.. Nick Kurtz will have the handedness advantage against Luis Castillo today... and the cherry on top, Castillo has a large platoon split.. Nick Kurtz has a 92nd percentile opposite-field rate on his flyballs (36%) and is a great match for the park considering he'll be hitting them in the direction of the game's 9th-shallowest LF fences in today's game.
Total Bases
Lawrence Butler logo
Lawrence Butler o1.5 Total Bases (+230)
Projection 1.41
Best Odds
Pick made: 2 minutes ago
EV Model Rating
Star rating: 4 out of 5
The leading projection system (THE BAT X) projects Lawrence Butler in the 80th percentile when it comes to his home run skill.. T-Mobile Park has the 9th-lowest fences in Major League Baseball.. Given Luis Castillo's large platoon split, Lawrence Butler will have a tremendous advantage hitting from the opposite side of the dish today.. Lawrence Butler has a 95th percentile opposite-field rate on his flyballs (37.2%) and will have a big advantage hitting them towards baseball's 9th-shallowest LF fences in today's matchup.. The Seattle Mariners infield defense profiles as the weakest among every team today.
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Los Angeles Dodgers logo LAD @ San Francisco Giants logo SF Tue, Apr 21 • 9:45 PM ET
4 Expert Picks 10 Computer Picks
FirstFiveInnings Run Line
Los Angeles Dodgers logo LAD FirstFiveInnings -0.5 (-115)
Best Odds
Pick made: 3 hours ago
Joe Osborne image
Joe Osborne
Senior Betting Analyst

The Dodgers have a clear early edge, leading MLB in runs scored in innings 1–5 on the road, while the Giants rank dead last at home. Los Angeles is also in better form, leading the league in OPS over the past week compared to San Francisco at 18th. Yoshinobu Yamamoto has been dominant, allowing just two earned runs in his last two starts and has owned Giants hitters, holding them to a combined .485 OPS in 79 at-bats, while Landen Roupp posted a 8.22 ERA in two appearances vs LA last season.

Total
Los Angeles Dodgers logo San Francisco Giants logo u7.5 (-125)
Best Odds
Pick made: 8 hours ago
JD Yonke image
JD Yonke
Betting Analyst

With temperatures in the mid-50s, it should be a pitcher-friendly environment. Yamamoto and Roupp have been two of the better starting pitchers in the league and should thrive. 

There are two quality bullpens behind them as well — L.A. ranks seventh in SIERA in relief (3.45) while San Francisco (3.55) isn’t far behind at ninth and has all of its top options well-rested and at the ready.

View 14 Picks

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