Travis Kelce Picks, Predictions & Best Bets for Friday Night Football Today

Find out why our NFL betting picks believe Travis Kelce (and Hollywood Brown) will benefit from a matchup with the Chargers defense in Week 1.

Neil Parker - Analyst at Covers.com
Neil Parker • Betting Analyst
Sep 5, 2025 • 15:46 ET • 4 min read
Kansas City Chiefs NFL Travis Kelce
Photo By - Imagn Images. Kansas City Chiefs tight end Travis Kelce (87) celebrates after a catch.

All eyes will be on the 2025 International Series on Friday, September 5 with the Kansas City Chiefs and star tight end Travis Kelce going up against the Los Angeles Chargers at Corinthians Arena in Sao Paulo, Brazil. 

Here are my NFL picks for the Travis Kelce odds ahead of this Week 1 AFC West clash tonight.

Travis Kelce prop pick

Travis Kelce best bet: Over 50.5 receiving yards (-110 at bet365)

While the best is definitely in the rearview mirror for the 10-time Pro Bowl tight end, Travis Kelce still projects as a go-to target in the Kansas City Chiefs offense.

I’m anticipating the Chiefs needing to attack through the air, too. The Los Angeles Chargers finished eighth in PFF run defense while allowing the ninth-lowest rush EPA, after all.

Kelce also has a long history of torching the Bolts, with 51 or more receiving yards in seven of his past eight games against Los Angeles. He’s also hit the triple-digit mark four times.

Additionally, while the Chargers were tough on opposing tight ends in terms of yards per target (6.16), they sported middling ranks in catch percentage (72.4%) and receptions (97) to the position.

A quick peek at the schedule also showcases Los Angeles faced the furthest thing from a string of tight ends headed to Canton, OH in 2024.

I also value K.C. quarterback Patrick Mahomes and head coach Andy Reid attacking on short and intermediate passes more than ever last year and expect the trend to continue. Mahomes threw for a career-low 7.0 yards per attempt, and Kelce has thrived on short and intermediate targets throughout his career.

Travis Kelce same-game parlay

Travis Kelce Over 50.5 receiving yards

Hollywood Brown Over 36.5 receiving yards

Justin Herbert Over 226.5 passing yards

Chargers quarterback Justin Herbert has aired it out for 236 or more yards in seven of nine games against the Chiefs, and he also threw for a career-high 7.7 yards per attempt last season. Los Angeles upgraded the talent surrounding Herbert heading into 2025, too.

Chiefs wide receiver Hollywood Brown has a go-to role in Week 1, and he also caught nine of 15 targets for 91 yards across his two regular-season games last year. Of course, Brown’s underlying numbers have also been solid with a 12.5 aDOT and 11.9 yards per reception for his career.

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Neil Parker - Covers
Betting Analyst

Neil Parker is, first and foremost, a sports fan. A huge supporter of the Cowboys, Cubs, and Maple Leafs, he has managed to parlay his passion into writing gigs at some of the top websites in the industry.

Neil takes a numbers-based approach to his handicapping and complements his in-depth statistical analysis with a keen eye on the markets to provide the best available odds. He loves to lean on his rolodex of idioms to offset his inner nerd. When it comes to wagering, he throws down on anything that catches his eye at bet365, Betway and BetVictor. He also keeps a close eye on CoolBet because the polar bear brand often has outlier NHL and NFL moneyline prices.

Neil graduated with honors from St. Thomas University in 2007 before completing his BEd at Acadia University in 2010. After teaching a myriad of courses and subjects, he found a groove delivering fun lessons to exceptional learners in non-traditional classroom environments. If his decade-plus teaching run taught him anything about sports betting, it’s to stay the course and use the summer – or offseason – to refresh and prepare to be better in the year to come.

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