Two stud quarterbacks meet on Sunday Night Football when the Tampa Bay Buccaneers sail west to take on the Los Angeles Rams.
Our Buccaneers vs. Rams predictions are chock-full of NFL picks for this marquee matchup on November 23.
Buccaneers vs Rams SNF predictions
- Buccaneers +6.5 (-110 at FanDuel)
- Over 49.5 (-108 at FanDuel)
- Davante Adams anytime TD (+185 at FanDuel)
- Baker Mayfield o242.5 pass yds (-114 at FanDuel)

Buccaneers vs Rams SNF best bets
Buccaneers +6.5
Jason Logan expects Baker Mayfield & Co. to go shot-for-shot with the Rams in L.A.
"The Bucs’ run defense won’t let Sean McVay get going on the ground, while the Tampa offense can trade shots with L.A. This spread is too big."
Over 49.5
JLo also expects points aplenty at SoFi on SNF.
"Tampa keeps scoring despite missing some key offensive weapons, and the Rams may have to pass more than they want against a stingy run-stopping unit. I bet the Over 49 earlier in the week and like this one below the key total of 51 points.
Buccaneers vs Rams SNF TD picks
Davante Adams
Quinn Allen thinks Matthew Stafford will link with his favorite red zone target tonight.
"Davante Adams has formed terrific chemistry with Matthew Stafford. The wideout only had one catch in a Week 11 win over the Seattle Seahawks, but it was for a touchdown. In fact, he’s found the end zone in four straight games, collecting seven touchdowns during that span. Adams is a real threat, especially in the red zone."
Buccaneers vs Rams SNF props
Baker Mayfield Over 242.5 passing yards
Rohit Ponnaiya expects Baker Mayfield to air it out on SNF.
"The Rams are 7-point home favorites, which should lead to a negative game script and high passing volume from the Bucs. That's been a theme for the 8-2 Rams, who have allowed the fifth-most pass attempts per game (36.4). This is a five-star play according to EV Analytics, which is projecting 263.2 passing yards for Mayfield.
Buccaneers vs Rams odds
Buccaneers vs Rams game info
| Location: | SoFi Stadium, Inglewood, CA |
| Date: | Sunday, November 23, 2025 |
| Kickoff: | 8:20 p.m. ET |
| TV: | NBC |
Buccaneers vs Rams latest injuries
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