College Football Week 14 Picks: ChatGPT Predicts the Winner of Every Big Game

Sit back and let AI take the wheel during Week 14 with moneyline picks for every matchup involving an AP Top-25 team.

Ryan Murphy - Managing Editor at Covers.com
Ryan Murphy • Managing Editor
Nov 26, 2025 • 10:25 ET • 4 min read
Ohio State Buckeyes quarterback Julian Sayin (10) warms up.
Photo By - Imagn Images. Ohio State Buckeyes quarterback Julian Sayin (10) warms up.

Rivalry Week is here, which means grudges, chaos, and more bad beats than your bankroll deserves. From backyard brawls to playoff-shaping showdowns, every snap suddenly feels like life or death for your tickets.

So this time, let the robot stress for you. We fed all the FanDuel lines into ChatGPT and told it to spit out straight up moneyline winners for every Week 14 matchup featuring an AP Top 25 team.

No spreadsheets, no late-night injury digging, just AI-made college football picks so you can plant on the couch, crack a beverage, and enjoy the carnage (mostly) sweat-free.

NCAAF Week 14 moneyline picks

Matchup Pick
No. 7 Mississippi Mississippi vs Mississippi State Mississippi State Mississippi  -290
No. 13 Utah Utah vs Kansas Kansas Utah  -480
No. 4 Georgia Georgia vs No. 23 Georgia Tech Georgia Tech Georgia  -650
No. 2 Indiana Indiana vs Purdue Purdue Indiana  -10000
No. 3 Texas A&M Texas A&M vs No. 16 Texas Texas Texas A&M  -120
No. 25 Arizona Arizona vs No. 20 Arizona State Arizona State Arizona  -118
No. 1 Ohio State Ohio State vs No. 15 Michigan Michigan Ohio State  -410
No. 5 Texas Tech Texas Tech vs West Virginia West Virginia Texas Tech  -3500
No. 12 Miami Miami vs No. 22 Pittsburgh Pittsburgh Miami  -255
UCF UCF vs No. 11 BYU BYU BYU  -1250
No. 6 Oregon Oregon vs Washington Washington Oregon  -260
LSU LSU vs No. 8 Oklahoma Oklahoma Oklahoma  -410
No. 14 Vanderbilt Vanderbilt vs No. 19 Tennessee Tennessee  Tennessee  -152
UCLA UCLA vs No. 17 USC USC USC  -2300
Virginia Tech Virginia Tech vs No. 18 Virginia Virginia Virginia  -360
No. 10 Alabama Alabama vs Auburn Auburn Alabama  -230
No. 21 SMU SMU vs Cal California SMU  -580
Charlotte Charlotte vs No. 24 Tulane Tulane Tulane  -10000
No. 9 Notre Dame Notre Dame vs Stanford Stanford Notre Dame  -20000

Odds courtesy of FanDuel.

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No. 7 Mississippi vs Mississippi State

Moneyline prediction: Mississippi (-290)
Odds: Mississippi -7.5; total 62.5.

The Egg Bowl can get weird, but FanDuel still has Mississippi as more than a touchdown favorite and -290 on the moneyline. That price reflects an expectation the Rebels simply have more ways to score over four quarters. Mississippi State’s generous underdog payout is tempting for rivalry-week chaos, yet the market is clearly leaning toward the ranked side taking care of business. For a straight up pick, Mississippi is the choice.

No. 13 Utah vs Kansas

Moneyline prediction: Utah (-480)
Odds: Utah -11.5; total 59.5.

Laying 11.5 on the road and priced at -480, Utah is being treated as clearly superior. That kind of moneyline suggests a comfortable win more often than not, even if Kansas can score enough to keep the spread interesting. Upsets happen, but backing a sizable favorite SU is usually how casual bettors stay alive through the early window. For a moneyline play only, the AI ride is with Utah.

No. 4 Georgia vs No. 23 Georgia Tech

Moneyline prediction: Georgia (-650)
Odds: Georgia -13.5; total 59.5.

This line screams “talent gap.” Georgia is nearly a two-touchdown favorite on the road and a hefty -650 on the moneyline. Georgia Tech has a live offense and rivalry motivation, but the odds say the Yellow Jackets need a lot to break their way to pull the upset. If you’re not chasing a longshot, it’s tough to argue against the team priced like a playoff contender. The pick to win outright is Georgia.

No. 2 Indiana vs Purdue

Moneyline prediction: Indiana (-10000)
Odds: Indiana -28.5; total 54.5.

When a team is laying 28.5 points and sits at -10000 on the moneyline, you’re not handicapping a winner, you’re asking whether the favorite can avoid total disaster. The number here essentially treats Indiana as a near lock to win, with Purdue needing almost everything to go right just to make it close. Upset hunters should look elsewhere. As a simple moneyline call, Indiana is the pick without overthinking it.

No. 3 Texas A&M vs No. 16 Texas

Moneyline prediction: Texas A&M (-120)
Odds: Texas A&M -2.5; total 51.5.

Finally, a number that looks like an actual coin flip. A&M is a narrow 2.5-point favorite and just -120 on the moneyline, signaling a game that could hinge on a late drive or key turnover. Texas offers a modest plus-money price for home-field believers, but the market’s tiny lean toward the Aggies is enough for this exercise. In a SU sense, I’ll follow the line and side with Texas A&M.

No. 25 Arizona vs No. 20 Arizona State

Moneyline prediction: Arizona (-118)
Odds: Arizona -1.5; total 48.5.

This is one of the tightest lines on the board. The market is sending a clear message: these rivals are basically equals, with a slight edge to the Wildcats. In spots like this, leaning into the side already shaded by the books is usually safer than trying to out-guess them. For a SU wager, I’ll ride with Arizona.

No. 1 Ohio State vs No. 15 Michigan

Moneyline prediction: Ohio State (-410)
Odds: Ohio State -10.5; total 44.5.

Ohio State enters as the deeper, more complete team, with high-end athletes at every level and a track record and efficiency metrics that show it thrives in big spots. Its offense combines explosive passing with a downhill run game, stressing Michigan vertically and horizontally.

Defensively, the Buckeyes have the speed to contain perimeter runs and force the Wolverines into uncomfortable passing downs. Special teams and overall depth also tilt slightly toward the Buckeyes, helping them withstand swings of momentum. Ohio State’s overall talent edge should prevail.

No. 5 Texas Tech vs West Virginia

Moneyline prediction: Texas Tech (-3500)
Odds: Texas Tech -23.5; total 53.5.

A 23.5-point spread and -3500 moneyline make Texas Tech one of the biggest favorites of the weekend. West Virginia’s +1280 is a fun lotto ticket, but this is the kind of game where the moneyline is primarily useful as a parlay piece, not a solo dart. Given how lopsided FanDuel’s projection is, it would be more surprising if Texas Tech lost outright than if it simply failed to cover.

No. 12 Miami vs No. 22 Pittsburgh

Moneyline prediction: Miami (-255)
Odds: Miami -6.5; total 51.5.

Miami as a 6.5-point favorite and -255 on the moneyline suggests modest but real separation. Pitt’s home crowd and +205 price will attract underdog players, yet the line still assumes the Hurricanes win this game more often than not. When you’re betting purely on who survives, you generally want the team with the shorter number unless you have strong information otherwise. Straight up, the AI pick is Miami.

UCF vs No. 11 BYU

Moneyline prediction: BYU (-1250)
Odds: BYU -17.5; total 47.5.

BYU is laying 17.5 and sits at -1250, positioning UCF as a sizable dog. That total Under 50 suggests a slower game script, meaning the spread is large relative to projected points, but the moneyline still implies BYU holds a big overall edge. Unless you’re banking on turnovers or special-teams chaos, the safer SU ticket is the ranked home team. I’ll trust the number and take BYU to win.

No. 6 Oregon vs Washington

Moneyline prediction: Oregon (-260)
Odds: Oregon -6.5; total 51.5.

Oregon is a 6.5-point road favorite with a -260 moneyline, which is meaningful respect in a potentially tricky spot. Washington’s +210 price reflects a realistic upset path, but not one the book expects more than about one time in three. Without current-season stats to lean on, I’m content to follow the market’s fairly strong confidence in the Ducks’ overall quality. Oregon handles business and gets the win.

LSU vs No. 8 Oklahoma

Moneyline prediction: Oklahoma (-410)
Odds: Oklahoma -10.5; total 36.5.

A total of just 36.5 paired with Oklahoma -10.5 creates an interesting profile: the market is projecting a low-scoring game where the Sooners still control things. LSU’s +320 moneyline is a big payoff for believers, but the spread and odds together suggest Oklahoma’s defense, pace, or both could tilt the contest. In low-total games, favorites can be vulnerable, yet the lines still lean heavily toward OU.

No. 14 Vanderbilt vs No. 19 Tennessee

Moneyline prediction: Tennessee (-152)
Odds: Tennessee -2.5; total 65.5.

At Tennessee -2.5 and -152 on the moneyline, this rivalry is priced like a competitive, high-scoring affair. The 65.5 total hints at plenty of fireworks, which can introduce variance, but the Vols are still the side getting the favorite tag. Vanderbilt’s +126 moneyline has appeal for plus-money chasers, yet the point spread keeps nudging us toward Tennessee as the slightly stronger team. For a straight-up pick, the call is Tennessee.

UCLA vs No. 17 USC

Moneyline prediction: USC (-2300)
Odds: USC -21.5; total 59.5.

USC enters as a massive favorite: -21.5 against the spread and -2300 on the moneyline, numbers that signal a huge perceived gap between the Trojans and Bruins. A total of 59.5 suggests a high-scoring game, and the market clearly expects USC to supply most of that offense. USC’s recruiting depth and quarterback play give it a higher ceiling. If the Trojans avoid turnovers and finish drives, their talent edge and home-field advantage should easily push them past UCLA on Saturday.

Virginia Tech vs No. 18 Virginia

Moneyline prediction: Virginia (-360)
Odds: Virginia -9.5; total 52.5.

Virginia giving 9.5 points and sitting at -360 on the moneyline indicates a clear but not overwhelming edge over its in-state rival. Hokies backers are rewarded with a +280 price, but you’re paying for real upset risk there. Rivalry volatility is always a concern, yet the line says Virginia is the more complete team in the aggregate.

No. 10 Alabama vs Auburn

Moneyline prediction: Alabama (-230)
Odds: Alabama -5.5; total 46.5

Alabama enters the Iron Bowl as a 5.5-point favorite and -230 on the moneyline at FanDuel, signaling clear market respect. Oddsmakers are essentially saying the Crimson Tide will win this game more often than not, thanks to superior depth, recruiting talent, and coaching stability.

Auburn’s +188 price reflects real upset potential at home, but a lower projected total of 46.5 suggests fewer possessions, which often benefits the more efficient, fundamentally sound side. If Alabama limits explosive plays, finishes drives in the red zone, and leans on its defensive front, they are well positioned to grind out a rivalry win this Saturday.

Charlotte vs No. 24 Tulane

Moneyline prediction: Tulane (-10000)
Odds: Tulane -29.5; total 52.5.

Tulane is an enormous 29.5-point favorite and a staggering -10000 on the moneyline, putting this in “only useful for parlays” territory. Charlotte’s +2800 number is massive, but it’s priced that way for a reason: the book sees a major gulf in quality. Anything can happen in college football, yet this is exactly the sort of spot where casual moneyline bettors tend to side with the ranked powerhouse. The SU call is Tulane.

No. 21 SMU vs California

Moneyline prediction: SMU (-580)
Odds: SMU -13.5; total 53.5.

California’s +420 is intriguing if you’re dead-set on a home upset angle, but the spread implies the Mustangs are multiple scores better on a neutral field. When books hang this kind of price, they’re usually confident in the favorite’s offensive ceiling and depth. For a straight-up wager, I’m comfortable backing SMU to come out on top.

No. 9 Notre Dame vs Stanford

Moneyline prediction: Notre Dame (-20000)
Odds: Notre Dame -32.5; total 51.5.

This is the biggest mismatch on your board. Notre Dame is laying 32.5 and carries an eye-watering -20000 moneyline, essentially saying a Fighting Irish loss would be one of the shocks of the season. Stanford’s +3500 number is pure lottery-ticket material. From a moneyline-only perspective, there’s almost no handicapping to do: the book expects Notre Dame to win easily. The AI prediction follows suit and takes Notre Dame straight-up.

ChatGPT has gone 193-47 so far this season for +128.45 units. 

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Ryan Murphy Managing Editor at Covers
Managing Editor

Ryan Murphy began his love affair with sports journalism at the age of nine when he wrote his first article about his little league baseball team. He has since authored his own weekly column for Fox Sports and has been a trusted voice within the sports betting industry for the past eight years with stops at XL Media and Churchill Downs. He’s been proud to serve as Managing Editor at Covers since 2022.

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