It’s going down Friday night in Tempe when the Arizona State Sun Devils host the TCU Horned Frogs in a matchup between two of the Big 12’s best teams.
See why I’m bullish on the Frogs with my TCU vs. Arizona State predictions and college football picks for Friday, September 26.
TCU vs Arizona State prediction
TCU vs Arizona State best bet: TCU +2.5 (-110)
Kenny Dillingham proved his worth a year ago when he brought the Arizona State Sun Devils from irrelevance to the playoffs, and don’t forget ASU was a 4th & 13 miracle conversion away from toppling Texas in the first round.
Still, I have to side with the TCU Horned Frogs on Friday night as they’ve simply looked like the superior squad through the first couple of weeks.
Josh Hoover (9.7 yards per attempt) is one of the best quarterbacks in the country. He commands a potent offense that should be able to take advantage of a beatable Arizona State defense ranked 96th in success rate.
On the flip side, Dillingham’s offense is still searching for its identity. He’s mostly opted for 12 personnel, slowing the game down and avoiding throwing the ball due to a one-dimensional attack that’s only featured one viable receiver thus far in Jordyn Tyson.
Sonny Dykes’ TCU squad looks like a true threat in the Big 12 and is firing on all cylinders.
TCU vs Arizona State same-game parlay
Wide receiver Eric McAlister was the star of the college football world in Week 4, catching eight passes for 254 yards and three scores against SMU.
He even had a fourth touchdown wiped off the board when he was ruled out of bounds, so he’s clearly a potent weapon and is primed for a monster season.
Sam Leavitt’s legs are going to be utilized a lot this season for an offense that’s bogged down in the red zone sans Cam Skattebo, and that’s evident in the quarterback’s rushing production (219 rushing yards and four touchdowns) through four games.
TCU vs Arizona State SGP
- TCU +2.5
- Eric McAlister anytime touchdown
- Sam Leavitt anytime touchdown
Our deep-ball SGP: Hoov away
Hoover has thrown for at least 280 yards in every game and will continue to be relied on every week, especially with starting running back Kevorian Barnes banged up.
TCU vs Arizona State SGP
- TCU +2.5
- Eric McAlister anytime touchdown
- Sam Leavitt anytime touchdown
- Josh Hoover Over 285.5 passing yards
TCU vs Arizona State odds
- Spread: TCU +2.5 | Arizona State -2.5
- Moneyline: TCU +110 | Arizona State -132
- Over/Under: Over 55.5 | Under 55.5
TCU vs Arizona State trend to know
TCU is 6-1 ATS in its last seven games. Find more college football betting trends for TCU vs Arizona State.
How to watch TCU vs Arizona State
| Location | Mountain America Stadium, Tempe, AZ |
| Date | Friday, September 26, 2025 |
| Kickoff | 9:00 p.m. ET |
| TV | FOX |
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