Tuesday night brings us a Sun Belt showdown between the South Alabama Jaguars and the Marshall Thundering Herd.
Given Marshall’s resume this season, I have a pretty easy time making my South Alabama vs. Marshall prediction. Find out why I’m backing the Jaguars below!
My college football picks have South Alabama handing the Thundering Herd their fourth loss of the season.
Kickoff is set for Tuesday, Oct. 20, at 7:30 p.m. ET on ESPN2.
TOP PICK
Who will win South Alabama vs Marshall: South Alabama moneyline
Don't be afraid to pay a little juice. With how crazy college football can get, this one feels like a weird spot, but I do endorse South Alabama -2.5, or -3 if you are not in the juice-paying business.
I'll just flat-out say it: Marshall sucks. Its resume is putrid. The Thundering Herd may be 3-3, but they're just 1-5 against the spread, and some of these performances have been pathetic.
Marshall nearly lost to Gardner-Webb as a 24.5-point favorite and almost lost to Middle Tennessee State as an 11.5-point favorite. The Thundering Herd are just a few plays away from looking exactly like their ATS record.
Marshall is coming off a loss to Coastal Carolina as a 4.5-point home favorite. The Thundering Herd racked up more than 505 total yards, outgaining the Chanticleers by nearly 200. How on earth did they fumble that game away? Turnovers. Marshall coughed up the ball three times on fumbles while throwing three interceptions.
The Jaguars should take care of business, as they've played every opponent tough. Their worst loss came against Kentucky, when they fell 45-21 as 20.5-point underdogs.
South Alabama ranks seventh in points per game but 130th in points allowed, which is a concern. However, Marshall ranks 116th in points allowed and 120th in yards allowed per game.
South Alabama or nothing here.

South Alabama vs Marshall Over/Under pick: Over 64.5
This matchup has utter chaos written all over it. Both defenses are allowing more than 33 points per game, while one offense is averaging just 22 points per game and the other is nearly hitting 40.
Although Marshall has struggled to score, it moves the ball well, and South Alabama's defense has been a revolving door. The Thundering Herd should finally find paydirt.
Despite ranking 111th in points per game, the Thundering Herd sit 64th in total offense, averaging 406.5 yards per game. If Marshall can bounce back and clean up its turnover problems, this game could soar over the total. Neither side has shown much ability to stop anyone.
I would not take this higher than it is.
South Alabama vs Marshall combo
If you’re feeling like getting your sweat on for a Tuesday night Sun Belt showdown, combo all three plays together and you’ll get 4.29x. That’s not a bad price considering how rough both defenses have been and how putrid Marshall has looked overall this season. Time to root for points and the Jaguars!
South Alabama vs Marshall combo
- South Alabama moneyline
- Over 64.5
- 1H Over 31.5
- 2026 picks: 56-42-3, +15.80 units
South Alabama vs Marshall odds
For help understanding probabilities, see our odds calculator.
- Spread: South Alabama -2.5 | Marshall +2.5
- Over/Under: Over 64.5 (51%) | Under 64.5 (50%)
- Moneyline: South Alabama 57% | Marshall 43%
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South Alabama vs Marshall weather
The weather in Huntington should be in the mid-60s at kickoff before slowly dipping into the 50s as the game goes on. Nothing but perfect football weather for a Tuesday night!
Check out our college football weather page for up-to-date info on every matchup.
South Alabama vs Marshall trend to know
The Over is 4-0 in the Jaguars' last four road games. Find more college football betting trends for South Alabama vs. Marshall.
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How to watch South Alabama vs Marshall
| Location | Joan C. Edwards Stadium, Huntington, W.Va. |
| Date | Tuesday, Oct. 20, 2026 |
| Kickoff | 7:30 p.m. ET |
| TV | ESPN2 |
South Alabama vs Marshall latest injuries
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Odds are correct at the time of publishing and are subject to change.
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