LSU vs Mississippi Odds, Picks, and Predictions: Tigers Ready to Roll the Rebels

James Bisson - Head of Content, Betting
James Bisson • Head of Content, Betting 16+ years betting experience
Updated: Sep 30, 2023 , 03:34 PM ET • 4 min read

It's a critical SEC West showdown between the LSU Tigers and Mississippi Rebels where both teams own identical 3-1 records. LSU is the team in better form having won three straight and our betting picks suggest form will hold serve here.

Jayden Daniels LSU NCAAF
Photo By - USA TODAY Sports

A massive SEC West showdown early in the season could set the tone for these two programs for the remainder of the campaign as the LSU Tigers and Mississippi Rebels are set to clash this evening.

The Rebels took a tough loss last week at Alabama, while the Tigers were able to sneak out a close home win over Arkansas. Can the Tigers take early control of the SEC West and cover the spread in the college football odds on the road? 

Here are my free college football picks for LSU vs. Mississippi at Vaught-Hemingway Stadium in Oxford, MS on Saturday, September 30. 

LSU vs Mississippi best odds

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LSU vs Mississippi picks and predictions

LSU started the season with a tough loss to Florida State on a neutral site in a game that was never close. However, they have bounced back nicely with consecutive SEC wins over Mississippi State and Arkansas. These games are more telling to what to expect in this matchup with Ole Miss than the Florida State game. 

Last season in this matchup with several of the same key players that will be in this matchup, Ole Miss jumped out to a 17-3 lead before getting destroyed 42-3 in the rest of the game. Quarterback Jayden Daniels threw for 248 yards and two touchdowns and rushed for 121 yards and three touchdowns for the Tigers. 

Thus far this season, Daniels has 1,296 yards and 12 touchdowns through the air with only two interceptions. He also has 193 yards rushing and two touchdowns. This has led the Tigers to hold a Top 10 scoring offense, the seventh-ranked offense in total yards, and fourth-best offense in first downs gained. 

The Rebels defense has been decent this season, but still ranks 61st in yards allowed. Last week, it allowed Alabama to total 356 total yards and Jalen Milroe to complete 17 of 21 passes despite his struggles with accuracy this season. Daniels will be a completely different beast to face. 

Ole Miss also has had some issues on special teams. They have allowed two blocked kicks and a blocked punt. They also rank 129th in the nation in net punt yards. Field position is something they cannot afford to give up to these Tigers who converted 15 of 21 red zone possessions into touchdowns. 

This is going to be a big game for Daniels and LSU much like last year, where he was able to attack both through the air on the ground. It will be a tough road environment at night, but the Tigers have shown they can handle it, winning four of their past five SEC road games. LSU to cover is my best bet of the game.

If you have an account with DraftKings, they are offering a 50% profit boost for one bet on this game; use it to increase the value of this bet from -112 to +133 — giving you a price on the LSU moneyline that is significantly better than anywhere else in the market.

My best bet: LSU -2.5 (-112 at DraftKings | +133 with profit boost)
Picks made at time of writing may not reflect live odds.

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LSU vs Mississippi same-game parlay

LSU -2.5

Jayden Daniels anytime TD

Jayden Daniels Over 280.5 passing yards

The Tigers will be able to put up plenty of points in this game and Daniels is going to be a big part of it. That gives us great opportunities for a same game parlay. 

Last year, Daniels was able to score three touchdowns on the ground against Ole Miss. He also has two rushing touchdowns already this season. I think we will see another one for Daniels in this game.

The Rebels are currently giving up 226.2 passing yards per game despite not facing any great passing offenses. Daniels is averaging 338.2 passing yards per game this season. This game will trend closer to Daniels’ average than Ole Miss’s average. 

Learn how to bet a same-game parlay with these helpful tips and strategies.

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LSU vs Mississippi spread and Over/Under analysis

LSU also has a huge advantage in staying on the field on offense. Ole Miss ranks 106th in third-down percentage at 35.4%. Meanwhile, the Tigers rank 5th at 58.0%. Ole Miss also ranks 129th in time of possession. The Rebels defense will wear down and LSU will run away late. 

Understandably, the total is extremely high in this game at 67.5 points. Last season, this game saw 65 points scored. The Tigers average 42.8 points per game and the Rebels average 42.0 points. However, this total is too high for my liking. 

The Rebels struggled to score last week with only 10 points. They also are mediocre in the red zone with 11 touchdowns and four field goals in 19 attempts. It will take a lot of Ole Miss scoring for the Over to hit here and I just do not trust them enough. 

LSU vs Mississippi betting trend to know

Ole Miss has hit the Team Total Under in their last three games at home. Find more college football betting trends for LSU vs Mississippi.

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LSU vs Mississippi game info

Location: Vaught-Hemingway Stadium, Oxford, MS
Date: Saturday, September 30, 2023
Kickoff: 6:00 p.m. ET
TV: ESPN

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James Bisson
Head of Content, Betting

James Bisson is the Editor-in-Chief at Covers. He has been a writer, reporter and editor for more than 20 years, including a nine-year stint with The Canadian Press and more than five years at theScore. He has covered dozens of marquee events including the 2010 Winter Olympics, the 2006 Stanley Cup final and Wrestlemania 23, and his work has appeared in more than 200 publications, including the Los Angeles Times, the Guardian, Yahoo! Sports, the Toronto Star and The Globe and Mail.

His book, “100 Greatest Canadian Sports Moments”, was a hardcover best-seller in Canada in 2008 and earned him appearances on CBC Radio and Canada AM. He has written more than 50 sportsbook reviews, more than 200 industry news articles, and dozens of other sportsbook-related content articles.

A graduate of the broadcast journalism program at Ryerson University (now Toronto Metropolitan University), James has been an avid bettor since the early 2000s, and cites bet365 as his favorite sports betting site due to its superior functionality and quick payouts. His biggest professional highlight: Covering Canada's first Olympic gold medal on home soil – and interviewing Bret Hart. Twice.

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