March Madness 2 vs 15 Seed History: Who Will Defy the Odds in 2025?

James Bisson - Head of Content, Betting
James Bisson • Head of Content, Betting 16+ years betting experience
Updated: Mar 17, 2025 , 09:08 AM ET • 4 min read

It's become increasingly common in recent years to see a No. 2 seed knock off a No. 15 seed in the NCAA Tournament. We examine every time it's happened and present the odds of it happening again in 2025.

Saint Peter's Peacocks head coach Shaheen Hollway reacts after defeating the Kentucky Wildcats during the first round of the 2022 NCAA Tournament.
Photo By - Imagn Images. Saint Peter's Peacocks head coach Shaheen Hollway reacts after defeating the Kentucky Wildcats during the first round of the 2022 NCAA Tournament.

Major upsets are a big part of what makes March Madness so special.

The No. 2 vs. No. 15 matchups always offer intrigue, as we’ve seen David topple Goliath many times throughout the years.

Below, we will look at the history of 15 seeds versus 2 seeds in the NCAA men’s basketball tournament.

How many times has a 15 seed beaten a 2 seed in March Madness?

In 156 NCAA Tournament matchups, the 15 seed has knocked off the 2 seed 11 times. That’s a record of 11-145. 

So, it happens... just not every year.

We did not see a 15-seed win last year. In 2023, however, Princeton stunned 2-seed Arizona. 

Crazy enough, that was the third straight March in which a 15 seed won a game. In 2022, Saint Peter’s shocked Kentucky, and in 2021 Oral Roberts defeated Ohio State.

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What are the odds that a 15 seed wins against a 2 seed?

Teams seeded No. 15 have a 7.05% chance of beating a 2 seed. These odds are increasing over time, likely due to more and more parity in college basketball.

Consider that in the 1990s, a 2 seed beating a 15 seed occurred just three times. In the 2000s, it happened just once.

The turning point happened early in the 2010s. In 2012, there were a pair of No. 15 vs. No. 2 upsets in the same tournament. Another came in 2013, and yet another came in 2016.

There have been three so far this decade, and we aren’t even halfway through it.


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No. 2 vs. No. 15 seed history

Here is a look at the 11 times a No. 15 seed has upset a No. 2 seed.

  • 2023: Princeton over Arizona, 59-55
  • 2022: Saint Peter’s over Kentucky, 85-79
  • 2021: Oral Roberts over Ohio State, 75-72
  • 2016: Middle Tennessee over Michigan State, 90-81
  • 2013: Florida Gulf Coast over Georgetown, 78-68
  • 2012: Norfolk State over Missouri, 86-84
  • 2012: Lehigh over Duke, 75-70
  • 2001: Hampton over Iowa State, 58-57
  • 1997: Coppin State over South Carolina, 78-65
  • 1993: Santa Clara over Arizona, 64-61
  • 1991: Richmond over Syracuse, 73-69

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James Bisson
Head of Content, Betting

James Bisson is the Editor-in-Chief at Covers. He has been a writer, reporter and editor for more than 20 years, including a nine-year stint with The Canadian Press and more than five years at theScore. He has covered dozens of marquee events including the 2010 Winter Olympics, the 2006 Stanley Cup final and Wrestlemania 23, and his work has appeared in more than 200 publications, including the Los Angeles Times, the Guardian, Yahoo! Sports, the Toronto Star and The Globe and Mail.

His book, “100 Greatest Canadian Sports Moments”, was a hardcover best-seller in Canada in 2008 and earned him appearances on CBC Radio and Canada AM. He has written more than 50 sportsbook reviews, more than 200 industry news articles, and dozens of other sportsbook-related content articles.

A graduate of the broadcast journalism program at Ryerson University (now Toronto Metropolitan University), James has been an avid bettor since the early 2000s, and cites bet365 as his favorite sports betting site due to its superior functionality and quick payouts. His biggest professional highlight: Covering Canada's first Olympic gold medal on home soil – and interviewing Bret Hart. Twice.

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