The Cleveland Cavaliers are riding a seven-game winning streak when they visit Paycom Center and the Oklahoma City Thunder.
The Cavs have also won five straight on the road, and my Cavaliers vs. Thunder predictions and NBA picks are backing Cleveland over shorthanded OKC on Sunday, February 22.
Cavaliers vs Thunder prediction
Cavaliers vs Thunder best bet: Cavaliers moneyline (-130)
The Cleveland Cavaliers have the edge as the Oklahoma City Thunder are missing two-way impact players in Shai Gilgeous-Alexander and Jalen Williams.
SGA and Williams aren’t just scorers. Their absence weakens the perimeter defense, a major concern given Donovan Mitchell and James Harden's recent hot hands.
Cleveland seeks an eighth straight win and is 5-0 with Harden in the lineup. The Cavaliers are the deeper, more complete group and are chasing a sixth consecutive road victory.
Rather than lay the points, I’ll back them on the moneyline against the shorthanded Thunder.
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Cavaliers vs Thunder same-game parlay
Evan Mobley has cleared his combo prop in ten of 11 games and had 21 points, rebounds, and assists in 19 minutes against Charlotte.
James Harden’s playmaking has stabilized Cleveland’s offense, and he’s dished at least nine in two of his five games with the Cavs, and twice he dropped eight.
Cavaliers vs Thunder SGP
- Cavaliers moneyline
- Mobley Over 21.5 P/R/A
- Harden Over 8.5 assists
Our "from downtown" SGP: Deep'n delicious
Jared McCain has knocked down two or more triples in four of seven games since joining the Thunder.
Cavaliers vs Thunder SGP
- Cavaliers moneyline
- Mobley Over 21.5 P/R/A
- Harden Over 8.5 assists
- McCain Over 1.5 threes
Cavaliers vs Thunder odds
- Spread: Cavaliers -1 | Thunder +1
- Moneyline: Cavaliers -115 | Thunder -105
- Over/Under: Over 223.5 | Under 223.5
Cavaliers vs Thunder betting trend to know
The Cleveland Cavaliers have hit the Moneyline in 14 of their last 16 games (+12.10 Units / 25% ROI). Find more NBA betting trends for Cavaliers vs. Thunder.
How to watch Cavaliers vs Thunder
| Location | Paycom Center, Oklahoma City, OK |
| Date | Sunday, February 22, 2026 |
| Tip-off | 1:00 p.m. ET |
| TV | ABC |
Cavaliers vs Thunder latest injuries
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