My Rockies vs. White Sox prediction and MLB picks for Sunday, Sept. 27, back Chicago as a 62% favorite.
After a 9-6 Rockies win on Saturday, Chicago looks to dominate Rockies left-hander Kyle Freeland to keep the hot bats alive heading into October.
The first pitch flies at 3:10 p.m. ET.
Who will win Rockies vs White Sox today: White Sox
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It is the Chicago White Sox or nothing in this matchup, as the South Siders draw veteran left-hander Kyle Freeland, who will likely be making his final start as a Rockie.
The southpaw from Colorado has the worst pitcher rating on the day over at Batters-Box, where he draws a lineup with not only six elite-rated hitters, but another with a strong rating. The White Sox are also the highest-rated team in the current season dataset.
Anthony Kay takes the bump for Chicago. He has not been the sexiest pitcher alive, but he has limited hard contact and barrels very well over his last five starts — holding opposing hitters to just a 35% hard-hit rate and an 8% barrel rate.
The White Sox have been turning it up at the plate over their last six games, posting a 117 wRC+, 43% hard-hit rate, and .761 OPS during that stretch.
The Colorado Rockies did have a great Saturday against the South Siders, but the White Sox left so many guys in scoring position. They will go all out in Game 162.
COVERS INTEL: The Rockies have posted a 64 wRC+, .278 wOBA, and 4.6% barrel rate over their last six games, per Handigraphs.
Rockies vs White Sox Over/Under pick: Over 8.5
Despite missing out on the AL Central, the White Sox can’t afford to let off the gas, as they finally seem to have snapped their cold streak.
Now they face a left-hander with a 10.13 ERA and 2.34 WHIP, while allowing a 55% hard-hit rate over his last three starts.
The White Sox left EIGHT guys on base in last night’s 9-6 loss. Both teams have extremely gritty, scrappy lineups, and I don’t see either side letting off the gas in Game 162. Over or nothing for this writer.
Rockies vs White Sox home run prediction: Chase Meidroth
One of the scrappiest bats in the Chicago White Sox lineup is easily second baseman Chase Meidroth, who owns an .833 SLG and .389 ISO while posting a 30% ground-ball rate and 15.4% barrel rate over his last 10 games.
Left-handed pitchers have been his bread and butter, as the 25-year-old has posted a 1.000 SLG and .480 ISO against the last 30 he has faced, while generating a 50% hard-hit rate and 12.5% barrel rate.
He has been a major spark plug for this team all season, and he is easily my favorite look in this matchup.
- 2026 Season: 532-1057, +2.50 units
- Home Run picks: 134-460, +29.10 units
Rockies vs White Sox weather
The weather at first pitch will be in the mid-60s with light winds, which should have little to no effect on the game. It should be a marvelous 162 on the South Side.
Rockies vs White Sox odds
- Moneyline: Rockies 39% | White Sox 62%
- Run line: Rockies +1.5 (56%) | White Sox -1.5 (44%)
- Over/Under: Over 8.5 (50%) | Under 8.5 (50%)
Rockies vs White Sox trend
The Chicago White Sox have hit the first five Innings team total Over in 29 of their last 45 games (+12.25 Units / 22% ROI). Find more MLB betting trends for Rockies vs. White Sox.
How to watch Rockies vs White Sox and game info
| Location | Rate Field, Chicago, IL |
| Date | Sunday, Sept. 27, 2026 |
| First pitch | 3:10 p.m. ET |
| TV | Rockies.TV, CHSN |
| Rockies starting pitcher | Kyle Freeland (4-11, 6.58 ERA) |
| White Sox starting pitcher | Anthony Kay (9-9, 4.53 ERA) |
Rockies vs White Sox latest injuries
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