The Milwaukee Brewers dropped the series opener to the St. Louis Cardinals 6-3 at Busch Stadium.
My Brewers vs. Cardinals predictions see the road team flipping the script, facing a pitcher they’ve enjoyed plenty of success against.
Let’s dive deeper into my daily MLB picks for Tuesday, May 5.
Who will win Brewers vs Cardinals today: Brewers moneyline (-110)
Brandon Sproat’s xFIP and SIERA are two full runs less than his ERA, suggesting he hasn’t pitched as poorly as it appears on the surface.
He has also improved as the season progressed. Sproat pitched more than 16 innings over his last three starts, allowing four, four, and six hits, respectively.
If he can keep the ball in the park, the Milwaukee Brewers will be in good shape.
Andre Pallante has posted some concerning numbers against lefties (47.2% hard-hit rate, 13.2% barrel rate), and the Brewers have plenty of good ones in their lineup.

Brewers vs Cardinals Over/Under pick: Under 8.0 (-120)
Sproat has done a better job of limiting baserunners of late. Untimely homers have led to bigger run totals, which is less of a concern in 50F weather, where the winds will be blowing in.
If Sproat can hold his own early, the Brewers will turn to an excellent bullpen that ranks fifth in xFIP and is tied for third in homers allowed per nine innings.
Colder weather and Pallante’s high ground-ball rate (50%) should allow the St. Louis Cardinals to limit the long ball. That’ll make it difficult to score runs in bulk, helping keep this game Under the total.
- ML/RL bets: 12-5, +4.88 units
- Over/Under bets: 7-10, -4.06 units
Brewers vs Cardinals odds
- Moneyline: Brewers -110 | Cardinals -110
- Run line: Brewers -1.5 (+160) | Cardinals +1.5 (-190)
- Over/Under: Over 8 (+100) | Under 8 (-120)
Brewers vs Cardinals trend
The Milwaukee Brewers have hit the Game Total Under in 15 of their last 25 away games (+5.25 Units / 19% ROI). Find more MLB betting trends for Brewers vs. Cardinals.
How to watch Brewers vs Cardinals and game info
| Location | Busch Stadium, St. Louis, MO |
| Date | Tuesday, May 5, 2026 |
| First pitch | 7:45 p.m. ET |
| TV | Brewers.TV, Cardinals.TV |
| Brewers starting pitcher | Brandon Sproat (0-2, 6.75 ERA) |
| Cardinals starting pitcher | Andre Pallante (3-2, 3.73 ERA) |
Brewers vs Cardinals latest injuries
Brewers vs Cardinals weather
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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