VILL 36.5 o56.5
LOU -36.5 u56.5
NORF 46.0 o56.0
UVA -46.0 u56.0
RICH 33.0 o51.0
NCST -33.0 u51.0
RUTG 3.5 o53.5
BC -3.5 u53.5
MIZZ -4.5 o51.5
KU 4.5 u51.5
USF 3.5 o46.0
ARMY -3.5 u46.0
ODU 19.5 o48.0
VT -19.5 u48.0
PSU -24.5 o51.0
TEM 24.5 u51.0
ETSU 35.5 o54.5
UNC -35.5 u54.5
ORE -22.5 o55.5
OKST 22.5 u55.5
WOF 11.5 o47.5
KENT -11.5 u47.5
ASU 15.5 o50.5
TAM -15.5 u50.5
HOW 56.5 o64.5
IU -56.5 u64.5
WSU 17.5 o49.0
KSU -17.5 u49.0
OKLA -5.5 o43.5
MICH 5.5 u43.5
APP 6.5 o56.5
ECU -6.5 u56.5
WEBB 27.5 o55.5
LIB -27.5 u55.5
WAKE -3.5 o50.0
PUR 3.5 u50.0
WKU 40.0 o55.0
UGA -40.0 u55.0
UTM 41.5 o56.5
WVU -41.5 u56.5
COLG 24.5 o49.5
CMU -24.5 u49.5
HC 30.5 o49.5
M-OH -30.5 u49.5
STON 15.5 o56.5
BALL -15.5 u56.5
UTSA 1.5 o66.0
TXST -1.5 u66.0
WEB 33.5 o53.5
COLO -33.5 u53.5
ALA -9.5 o48.0
UK 9.5 u48.0
RICE 44.5 o55.0
ND -44.5 u55.0
EMU 17.5 o50.0
MSU -17.5 u50.0
MD -11.5 o52.0
CONN 11.5 u52.0
MSST -1.5 o55.0
MINN 1.5 u55.0
ARIZ 7.5 o48.0
BYU -7.5 u48.0
UCF 7.5 o56.5
PITT -7.5 u56.5
SHU 23.5 o53.5
MASS -23.5 u53.5
CCSU 35.5 o55.5
TOL -35.5 u55.5
DUKE 5.5 o51.5
ILL -5.5 u51.5
CAL 3.5 o56.5
SYR -3.5 u56.5
RMU 27.5 o42.5
AKR -27.5 u42.5
USU 27.5 o55.5
WASH -27.5 u55.5
ULM 9.5 o54.0
UAB -9.5 u54.0
WAG 45.5 o54.5
JMU -45.5 u54.5
UNLV -3.5 o58.0
UNT 3.5 u58.0
MERCY 41.5 o52.5
UNM -41.5 u52.5
ALST 22.5 o51.5
TROY -22.5 u51.5
UCD 25.5 o58.5
SMU -25.5 u58.5
UNCO 22.5 o47.5
WYO -22.5 u47.5
DEL 20.5 o54.5
VAN -20.5 u54.5
CAMP 49.5 o66.5
FLA -49.5 u66.5
JVST 2.5 o50.0
OHIO -2.5 u50.0
BUFF 9.5 o47.5
FIU -9.5 u47.5
MEM 8.5 o56.5
BSU -8.5 u56.5
MONM 25.5 o52.5
WMU -25.5 u52.5
SUU 20.5 o57.5
CSU -20.5 u57.5
TENN -12.5 o56.0
GT 12.5 u56.0
MTU 13.5 o57.0
MRSH -13.5 u57.0
GSU 8.5 o54.5
KENN -8.5 u54.5
ILST -3.5 o47.5
NIU 3.5 u47.5
TOWS 43.5 o55.5
SOCAR -43.5 u55.5
BGSU 30.0 o50.0
NEB -30.0 u50.0
WGEO 31.5 o56.5
ARST -31.5 u56.5
TLSA -13.5 o51.5
SHSU 13.5 u51.5
WCU 36.5 o60.5
CIN -36.5 u60.5
LIN 19.5 o52.5
MOSU -19.5 u52.5
USA 9.5 o49.5
TULN -9.5 u49.5
SOU 51.5 o60.5
HOU -51.5 u60.5
SDSU 12.5 o55.0
UCLA -12.5 u55.0
WIU 38.5 o48.5
WIS -38.5 u48.5
LT 35.0 o56.0
LSU -35.0 u56.0
NAVY -4.5 o59.0
FAU 4.5 u59.0
ISU 14.5 o41.0
IOWA -14.5 u41.0
GASO 19.5 o55.0
CLEM -19.5 u55.0
TTU -26.5 o53.5
ORST 26.5 u53.5
FOR 33.5 o53.5
CCU -33.5 u53.5
OSU 1.5 o52.0
TEX -1.5 u52.0
USM 33.0 o56.5
AUB -33.0 u56.5
CHAR 45.5 o60.5
MISS -45.5 u60.5
PV 38.5 o54.5
BAY -38.5 u54.5
GRAM 43.5 o54.5
TCU -43.5 u54.5
TXSO 26.5 o53.5
UTEP -26.5 u53.5
CP 20.5 o56.5
SJSU -20.5 u56.5
NDSU -2.5 o47.0
AFA 2.5 u47.0
ARK 12.5 o55.0
UTAH -12.5 u55.0
CSUS 17.5 o45.0
FRES -17.5 u45.0
MTST -3.5 o49.5
NEV 3.5 u49.5
ULL 31.0 o59.5
USC -31.0 u59.5
NMSU 7.5 o50.0
HAW -7.5 u50.0
Final Sep 10
FAMU 7 59.5 o65.0
MIA 77 -59.5 u65.0
Iowa State 7th Big 121-0
Iowa 4th Big Ten1-0

Iowa State vs Iowa   Picks & Props

ISU vs IOWA Picks

NCAAF Picks
Game Prop
Iowa State Cyclones image thumbnail u13.5 Team Total (-127)
Best Odds
Pick made: 2 hours ago
Rob Paul logo
Rob Paul
Betting Analyst

Iowa State has a massive talent disadvantage in this game, with eight of its 11 starters being transfers from the G6 or FCS level. That includes QB Jaylen Raynor, who struggled in P4 matchups while at Arkansas State. In four starts against P4 programs the last two years, Raynor's team averaged 13.7 PPG. And this Iowa defense is better than any he's faced (it's ranked No. 11 by SP+).

Total
Iowa State Cyclones image thumbnail Iowa Hawkeyes image thumbnail u41.5 (-116)
Best Odds
Pick made: 2 hours ago
Rob Paul logo
Rob Paul
Betting Analyst

New Iowa State starting QB Jaylen Raynor was terrible against P4 opponents while at Arkansas State. In four games against P4 teams, Raynor accounted for 11 turnover-worthy plays and threw just one TD. Iowa's defense is one of the best (ranked 11th by SP+), but its offense leans heavily on the run game, which will help the Under.

Passing Yards
JR Jaylen Raynor u149.5 Passing Yards (-115)
Best Odds
Pick made: 5 hours ago
JD Yonke logo
JD Yonke
Betting Analyst

Jaylen Raynor completed just eight of his 16 pass attempts in the opener against an FCS school, so it's difficult to expect much from him against Iowa. The Cyclones have a green offensive line that has 15 career FBS starts and features zero full-time FBS starters, making life difficult for Raynor and this entire offense in a slow-paced contest.

Receiving Yards
TD Tony Diaz o49.5 Receiving Yards (-155)
Best Odds
Pick made: 5 hours ago
JD Yonke logo
JD Yonke
Betting Analyst

Diaz hails from UT Rio Grande Valley, where he was a Freshman All-American after catching 68 passes for 890 yards and 11 touchdowns. He saw a whopping 13 targets in the opener, which he took for 84 yards and a score. He's in line to be the alpha of this pass-catching corps and very well may be the best wideout this program has seen in a long hwile. 

Receiving Yards
DV DJ Vonnahme o33.5 Receiving Yards (-114)
Best Odds
Pick made: 5 hours ago
JD Yonke logo
JD Yonke
Betting Analyst

Vonnahme is the latest edition of what "Tight End U" has to offer. He averaged 74 receiving yards over the final five games of 2025 and has 42 yards in the opener. He averaged the highest yards per route run (3.1) of any returning tight end and is in store for a monster season.

Spread
Iowa Hawkeyes image thumbnail IOWA -13.5 (-120)
Best Odds
Pick made: yesterday
Colby Marchio logo
Colby Marchio
Contributor

Iowa returns home for another edition of the Cy-Hawk rivalry, and the Hawkeyes have a great opportunity to finally take care of business against Iowa State. The Cyclones have won three of the last four meetings, but this is a different program after Matt Campbell’s departure for Penn State. Iowa, meanwhile, remains under longtime head coach Kirk Ferentz. With the rivalry meaning so much to both sides, expect the Hawkeyes to be locked in from the opening whistle. Iowa has already lost the last two meetings by a combined 4 points, but I’m backing the Hawkeyes to win by two touchdowns.

Spread
Iowa Hawkeyes image thumbnail IOWA -13.5 (-120)
Best Odds
Pick made: 3 days ago
Rob Paul logo
Rob Paul
Betting Analyst

The battle for the Cy-Hawk Trophy is set to be lopsided this year, with Iowa State being a completely different team than last year. New head coach Jimmy Rogers is relying heavily on G6 and FCS transfers to bolster a roster that ranked outside the Top 100 in returning production (45%). Iowa, meanwhile, has a dominant offensive line once again and a defense ranked Top 20 by SP+. 

3 LEG PARLAY
Iowa State Cyclones image thumbnail Iowa Hawkeyes image thumbnail
1st Half u20.5
1st Half Total
Iowa Hawkeyes image thumbnail
IOWA -14.5
Spread
Iowa State Cyclones image thumbnail Iowa Hawkeyes image thumbnail
u41.5
Total
Bet now
Pick made: an hour ago
Rob Paul logo
Rob Paul
Betting Analyst

The Cy-Hawk series tends to lack offense, and that should be especially true this year because of Iowa State. In Week 1 against a bad FCS team, the Cyclones had just 303 total yards. Against an Iowa defense ranked 11th by SP+, Iowa State will struggle to put up more than 13 points. An ugly first half should give way to Iowa's ground attack owning the second half.

Passing Yards
JR
Jaylen Raynor o144.5 Passing Yards (-115)
Projection 168.6827 (Over)
Best Odds
Pick made: 10 hours ago
EV Model Rating
Star rating: 5 out of 5
Receiving Yards
TD
Tony Diaz o51.5 Receiving Yards (-115)
Projection 60.8144 (Over)
Best Odds
Pick made: 3 hours ago
EV Model Rating
Star rating: 5 out of 5
Receiving Yards
KM
Kamari Moulton o3.5 Receiving Yards (-120)
Projection 8.0108 (Over)
Best Odds
Pick made: 10 hours ago
EV Model Rating
Star rating: 5 out of 5
Receiving Yards
DV
DJ Vonnahme o32.5 Receiving Yards (-114)
Projection 35.4697 (Over)
Best Odds
Pick made: 16 hours ago
EV Model Rating
Star rating: 4 out of 5

ISU vs IOWA Consensus Picks

More Consensus

Consensus Picks

Our consensus picks show you what percentage of the public is betting on, you'll need to decide whether you want to bet with or against the public.

Spread

63% picking Iowa State

63%
37%

Total Picks ISU 307, IOWA 180

Spread
ISU
IOWA
Total

54% picking Iowa State vs Iowa to go Under

46%
54%

Total PicksISU 140, IOWA 166

Total
Over
Under

ISU vs IOWA Props

GAME & PLAYER PROPS PROJECTIONS ANALYSIS BEST ODDS
PASSING YARDS
ISU
Iowa State Cyclones image thumbnail
J. Raynor (QB) o144.5 Passing Yards
168.68 OVER PROJECTION
+24.2 DIFFERENCE
26.04% EV
Rating: Star rating: 5 out of 5
Best odds bet365
Best Odds
ISU
Iowa State Cyclones image thumbnail
J. Raynor (QB) o144.5 Passing Yards

PROJECTION

168.68 OVER PROJECTION
+24.2 DIFFERENCE
26.04% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o144.5 -115
bet365 logo
RECEIVING YARDS
IOWA
Iowa Hawkeyes image thumbnail
T. Diaz (WR) o51.5 Receiving Yards
60.81 OVER PROJECTION
+9.3 DIFFERENCE
25.39% EV
Rating: Star rating: 5 out of 5
Best odds Fanatics Sportsbook
Best Odds
IOWA
Iowa Hawkeyes image thumbnail
T. Diaz (WR) o51.5 Receiving Yards

PROJECTION

60.81 OVER PROJECTION
+9.3 DIFFERENCE
25.39% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o49.5 -125
Fanatics Sportsbook logo
RECEIVING YARDS
IOWA
Iowa Hawkeyes image thumbnail
K. Moulton (RB) o3.5 Receiving Yards
8.01 OVER PROJECTION
+4.5 DIFFERENCE
25.26% EV
Rating: Star rating: 5 out of 5
Best odds bet365
Best Odds
IOWA
Iowa Hawkeyes image thumbnail
K. Moulton (RB) o3.5 Receiving Yards

PROJECTION

8.01 OVER PROJECTION
+4.5 DIFFERENCE
25.26% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o3.5 -120
bet365 logo
RECEIVING YARDS
IOWA
Iowa Hawkeyes image thumbnail
D. Vonnahme (TE) o32.5 Receiving Yards
35.47 OVER PROJECTION
+3.0 DIFFERENCE
19.73% EV
Rating: Star rating: 4 out of 5
Best odds bet365
Best Odds
IOWA
Iowa Hawkeyes image thumbnail
D. Vonnahme (TE) o32.5 Receiving Yards

PROJECTION

35.47 OVER PROJECTION
+3.0 DIFFERENCE
19.73% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o31.5 -115
bet365 logo
RECEPTIONS
IOWA
Iowa Hawkeyes image thumbnail
K. Moulton (RB) o0.5 Receptions
1.00 OVER PROJECTION
+0.5 DIFFERENCE
-21.43% EV
Rating: Star rating: 1 out of 5
Best odds bet365
Best Odds
IOWA
Iowa Hawkeyes image thumbnail
K. Moulton (RB) o0.5 Receptions

PROJECTION

1.00 OVER PROJECTION
+0.5 DIFFERENCE
-21.43% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o0.5 -220
bet365 logo
  • Proj. Diff: Low to High
  • Proj. Diff: High to Low
  • Proj. Rating: Low to High
  • Proj. Rating: High to Low
  • +EV: Low to High
  • +EV: High to Low
PASSING YARDS
ISU
Iowa State Cyclones image thumbnail
J. Raynor (QB) o144.5 Passing Yards
168.68 OVER PROJECTION
+24.2 DIFFERENCE
26.04% EV
Rating: Star rating: 5 out of 5
Best odds bet365
Best Odds
ISU
Iowa State Cyclones image thumbnail
J. Raynor (QB) o144.5 Passing Yards

PROJECTION

168.68 OVER PROJECTION
+24.2 DIFFERENCE
26.04% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o144.5 -115
bet365 logo
RECEIVING YARDS
IOWA
Iowa Hawkeyes image thumbnail
T. Diaz (WR) o51.5 Receiving Yards
60.81 OVER PROJECTION
+9.3 DIFFERENCE
25.39% EV
Rating: Star rating: 5 out of 5
Best odds Fanatics Sportsbook
Best Odds
IOWA
Iowa Hawkeyes image thumbnail
T. Diaz (WR) o51.5 Receiving Yards

PROJECTION

60.81 OVER PROJECTION
+9.3 DIFFERENCE
25.39% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o49.5 -125
Fanatics Sportsbook logo
RECEIVING YARDS
IOWA
Iowa Hawkeyes image thumbnail
K. Moulton (RB) o3.5 Receiving Yards
8.01 OVER PROJECTION
+4.5 DIFFERENCE
25.26% EV
Rating: Star rating: 5 out of 5
Best odds bet365
Best Odds
IOWA
Iowa Hawkeyes image thumbnail
K. Moulton (RB) o3.5 Receiving Yards

PROJECTION

8.01 OVER PROJECTION
+4.5 DIFFERENCE
25.26% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o3.5 -120
bet365 logo
RECEIVING YARDS
IOWA
Iowa Hawkeyes image thumbnail
D. Vonnahme (TE) o32.5 Receiving Yards
35.47 OVER PROJECTION
+3.0 DIFFERENCE
19.73% EV
Rating: Star rating: 4 out of 5
Best odds bet365
Best Odds
IOWA
Iowa Hawkeyes image thumbnail
D. Vonnahme (TE) o32.5 Receiving Yards

PROJECTION

35.47 OVER PROJECTION
+3.0 DIFFERENCE
19.73% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o31.5 -115
bet365 logo
RECEPTIONS
IOWA
Iowa Hawkeyes image thumbnail
K. Moulton (RB) o0.5 Receptions
1.00 OVER PROJECTION
+0.5 DIFFERENCE
-21.43% EV
Rating: Star rating: 1 out of 5
Best odds bet365
Best Odds
IOWA
Iowa Hawkeyes image thumbnail
K. Moulton (RB) o0.5 Receptions

PROJECTION

1.00 OVER PROJECTION
+0.5 DIFFERENCE
-21.43% EV

ANALYSIS

There is no analysis available at the moment. Please check back later.

o0.5 -220
bet365 logo

ISU vs IOWA Top User Picks

More Picks

User Picks

Our user picks are made by you, our valued users - we highlight the best user picks, sharing the users who are on a hot streak.

Spread

'johnmartellejr' is picking Iowa State to cover (+14.5)

johnmartellejr is #1 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Total

'johnmartellejr' picks Iowa State vs Iowa to go Under (42.5)

johnmartellejr is #1 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Total

'mlevine' picks Iowa State vs Iowa to go Under (41.5)

mlevine is #1 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Spread

'mlevine' is picking Iowa to cover (-13.5)

mlevine is #1 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Spread

'jrw424' is picking Iowa State to cover (+13.5)

jrw424 is #2 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Total

'stjula' picks Iowa State vs Iowa to go Over (42.5)

stjula is #4 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Spread

'stjula' is picking Iowa to cover (-11.5)

stjula is #4 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Total

'Monsmon45' picks Iowa State vs Iowa to go Under (42.5)

Monsmon45 is #5 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Spread

'tasok' is picking Iowa to cover (-14.5)

tasok is #5 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Spread

'Monsmon45' is picking Iowa State to cover (+14.5)

Monsmon45 is #5 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Total

'tasok' picks Iowa State vs Iowa to go Under (41.5)

tasok is #5 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Total

'ChiTownSteppers' picks Iowa State vs Iowa to go Over (41.5)

ChiTownSteppers is #7 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Total

'csmooth515' picks Iowa State vs Iowa to go Under (42.5)

csmooth515 is #7 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Spread

'csmooth515' is picking Iowa State to cover (+14.5)

csmooth515 is #7 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Spread

'ChiTownSteppers' is picking Iowa State to cover (+14.5)

ChiTownSteppers is #7 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Total

'sportsdool1123' picks Iowa State vs Iowa to go Under (42.5)

sportsdool1123 is #8 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Spread

'sportsdool1123' is picking Iowa State to cover (+11.5)

sportsdool1123 is #8 on picking games that Iowa State is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Total

'Technique' picks Iowa State vs Iowa to go Under (42.5)

Technique is #8 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Total
Over
Under
Spread

'Technique' is picking Iowa State to cover (+14.5)

Technique is #8 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA
Spread

'whosat' is picking Iowa State to cover (+13.5)

whosat is #9 on picking games that Iowa is in with a record of (1-0-0) and +1000 units on the season.

Spread
ISU
IOWA

Pages Related to This Topic

Weather Forecast

//Trends script for picks tab