Colts 3rd AFC South8-9

Rams 2nd NFC West12-5

4:05PM ET Sep 28, 2025

FOX

Colts @ Rams Odds

Game Odds

Game Odds Indianapolis Colts vs. Los Angeles Rams
	Spread	Total	Moneyline
Sports.OddsComparison.BettingLines.Models.BettingSide.SpreadBettingSideVm Indianapolis	+3.5 -105	o49.0 -118	+162
Sports.OddsComparison.BettingLines.Models.BettingSide.SpreadBettingSideVm L.A. Rams	-3.5 -105	u49.5 -105	-185

Spread

Game Odds Indianapolis Colts vs. Los Angeles Rams
	IND	LA
	+3.5 -105	-3.5 -105

Odds Comparison

ALL BOOKS	IND	LA
DraftKings logo	+3.5 -105	-3.5 -115
bet365 logo	+3.5 -115	-3.5 -105
FanDuel logo	+3.5 -118	-3.5 -112
BetMGM logo	+3.5 -115	-3.5 -105
Caesars logo	+3.5 -115	-3.5 -105

Total

Game Odds vs.
	OVER	UNDER
	o49.0 -118	u49.5 -105

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	o49.5 -115	u49.5 -105
bet365 logo	o49.5 -110	u49.5 -110
FanDuel logo	o49.5 -110	u49.5 -118
BetMGM logo	o49.0 -118	u49.0 -110
Caesars logo	o49.5 -110	u49.5 -110

Moneyline

Game Odds Indianapolis Colts vs. Los Angeles Rams
	IND	LA
	+162	-185

Odds Comparison

ALL BOOKS	IND	LA
DraftKings logo	+154	-185
bet365 logo	+155	-185
FanDuel logo	+146	-188
BetMGM logo	+155	-190
Caesars logo	+162	-195

Passing Yards

Matthew Stafford Projection 272.17

Game Odds vs.
OVER	UNDER
o251.5 -112	u255.5 -115

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	o253.5 -111	u253.5 -113
bet365 logo	-	-
FanDuel logo	o251.5 -112	u251.5 -112
BetMGM logo	o255.5 -115	u255.5 -115
Caesars logo	o251.5 -125	u251.5 -110

Daniel Jones Projection 227.64

Game Odds vs.
OVER	UNDER
o216.5 -115	u219.5 -111

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	o218.5 -112	u218.5 -112
bet365 logo	-	-
FanDuel logo	o219.5 -112	u219.5 -112
BetMGM logo	o216.5 -115	u216.5 -115
Caesars logo	o219.5 -121	u219.5 -111

Rushing Yards

Jonathan Taylor Projection 70.81

Game Odds vs.
OVER	UNDER
o86.5 -110	u89.5 -115

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	o86.5 -110	u86.5 -115
bet365 logo	-	-
FanDuel logo	o87.5 -112	u87.5 -112
BetMGM logo	o89.5 -115	u89.5 -115
Caesars logo	o87.5 -113	u87.5 -120

Kyren Williams Projection 65.8

Game Odds vs.
OVER	UNDER
o69.5 -112	u71.5 -120

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	o70.5 -114	u70.5 -110
bet365 logo	-	-
FanDuel logo	o69.5 -112	u69.5 -112
BetMGM logo	o71.5 -110	u71.5 -120
Caesars logo	o70.5 +100	u70.5 -135

Daniel Jones Projection 33.26

Game Odds vs.
OVER	UNDER
o24.5 -110	u26.5 -115

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	o26.5 -109	u26.5 -115
bet365 logo	-	-
FanDuel logo	o25.5 -112	u25.5 -112
BetMGM logo	o24.5 -110	u24.5 -118
Caesars logo	o25.5 -115	u25.5 -117

Matthew Stafford Projection 1.12

Game Odds vs.
OVER	UNDER
o0.5 +145	u0.5 -200

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	-	-
bet365 logo	-	-
FanDuel logo	-	-
BetMGM logo	o0.5 +145	u0.5 -200
Caesars logo	-	-

Game Odds vs.
OVER	UNDER
o2.5 -118	u2.5 -115

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	-	-
bet365 logo	-	-
FanDuel logo	-	-
BetMGM logo	o2.5 -118	u2.5 -115
Caesars logo	-	-

Game Odds vs.
OVER	UNDER
o21.5 -112	u22.5 -116

Odds Comparison

ALL BOOKS	OVER	UNDER
DraftKings logo	o22.5 -108	u22.5 -116
bet365 logo	-	-
FanDuel logo	o21.5 -112	u21.5 -112
BetMGM logo	o22.5 -110	u22.5 -118
Caesars logo	o21.5 -138	u21.5 +105

Receiving Yards

Receptions Made

Rushing Attempts

Passing Attempts

Passing Completions

Interceptions Thrown

Rush and Rec Yards

Passing and Rushing Yards

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