Texans vs Panthers Prediction, Picks & Odds for Tonight's NFL Preseason Game

Shawn Krest - Betting Analyst at Covers.com
Shawn Krest • Betting Analyst 20+ years betting experience
Updated: Aug 28, 2026 , 06:00 AM ET • 4 min read

Carolina’s backups have delivered this preseason, and with both teams resting their starters, I’m backing the Panthers and the Over in Friday’s finale.

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Carolina Panthers quarterback Kenny Pickett (12) hands off to running back Anthony Tyus III.
Photo By - Reuters Connect. arolina Panthers quarterback Kenny Pickett (12) hands off to running back Anthony Tyus III.

The bad news for the Carolina Panthers is that they got dominated by the Houston Texans in a joint practice on Wednesday, losing badly on both sides of the ball in an effort that Carolina coach Dave Canales called “lopsided.”

The good news for the Panthers is that none of those guys will play in Friday’s preseason finale.

That’s why my Texans vs. Panthers predictions call for Carolina to win.

Check out our latest NFL picks for more preseason betting analysis.

Texans vs Panthers prediction

Pick Kalshi
Probability
Panthers moneyline 49%
Over 36.5 49%

Percentages courtesy of Kalshi, one of the best prediction market apps.

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Who will win Texans vs Panthers: Panthers moneyline

Kalshi probability: 49%

Both coaches plan to rest their starters in the final preseason game, allowing the second- and third-string units to resolve any remaining depth-chart or roster-spot battles. That’s bad news for a Houston Texans team whose starters have won the first quarters of their two preseason games by a combined 20-3 margin. Houston has lost the second halves of its games by a 36-0 margin this preseason and has been outscored 44-3 after the first quarter.

The Carolina Panthers have been just the opposite. The starting unit has managed just one first-quarter touchdown in three games while the starting defense has allowed 13 points. Carolina’s reserves have then scored 74 points after the first quarter ends and 37 in the second halves.

 TOP PICK
Texans vs Panthers Over/Under pick: Over 36.5

Kalshi probability: 49%

As good as the Panthers’ offense has been after the starters depart, the Carolina defense has made opposing reserves look just as good. The Panthers have given up as many second-half points as they’ve scored — 37 — and have surrendered 63 after the first quarter. The Houston defense is also shaky, blowing a 17-0 lead against Oakland.

While Houston won’t have any starters in the game, there will be plenty of star power catching passes from the backup quarterbacks. The team has added Zay Jones and Sterling Shepard, then traded for Kayshon Boutte. The trio have combined for 22 NFL seasons, 381 games, 823 catches, and 52 touchdowns, and all will be making their preseason debut with Houston.

Covers COVERS INTEL: Brett Rypien, who will see time for Houston in this game after backup Davis Mills, hasn’t thrown a pass in the NFL since 2023. He was signed after the first preseason game, when expected third-string quarterback Graham Mertz suffered a season-ending injury. In his first action, he threw an interception, lost a fumble, and failed to lead the Texans to a point. He may be playing for his job, as the Texans could opt to start the year with only two quarterbacks.

Texans vs Panthers trend to know

The Panthers have gone Over in all three of their preseason games. Combined, the Over is 4-1 in the two teams’ five preseason games.

Texans vs Panthers live odds

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Texans vs Panthers weather

Temperatures will be in the 80s with a chance of a heavy thunderstorm, which could create wet conditions and potentially impact the passing and kicking games.

How to watch Texans vs Panthers

Location Bank of America Stadium, Charlotte, NC
Date Friday, Aug. 28, 2026
Kickoff 7 p.m. ET
TV KTRK, WSOC

Texans vs Panthers latest injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Shawn Krest
Betting Analyst

Since quitting his job as bank assistant vice-president in 2000, Shawn has covered Final Fours, Super Bowls, World Series games and title fights in boxing and UFC. His work has appeared on ESPN, MLB.com, Sports Illustrated and dozens of other outlets. His book, Baseball Meat Market was published in 2018. He lives in North Carolina with his dog Toby, eight turtles, and wife.

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