Seahawks vs Titans Prediction, Picks & Odds for Tonight's NFL Preseason Game

Jason Ence - Contributor at Covers.com
Jason Ence • Betting Analyst 13+ years betting experience
Updated: Aug 22, 2026 , 03:28 PM ET • 4 min read

With the Titans starters expected to see considerable playing time, we're backing Tennessee to cover as a 4.5-point favorite.

NFL

Match starts: 26 hrs
SEA
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TEN
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EXPERT PICK - SPREAD
Tennessee -4.5 (-103) Tennessee -4.5 (-103)
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Cam Ward of the Tennessee Titans NFL
Photo By - Reuters Connect. Cam Ward of the Tennessee Titans NFL

Robert Saleh has confirmed the Tennessee Titans will run Cam Ward and the starting unit out for a large portion of Sunday night's NFL preseason game against the Seattle Seahawks.

That's why the Titans (-4.5) are favored to win at home, and a key reason why I'm backing them to do just that.

I also explain why scoring will be at a premium in my Seahawks vs. Titans prediction and NFL picks with kickoff at 8 p.m. ET in Nashville. 

Seahawks vs Titans predictions

Pick Kalshi
Probabillity
Titans -4.5 48%
Under 37.5 48%

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Who will win Seahawks vs Titans: Titans -4.5 

Kalshi probability: 48%

We touched on last week how seriously Robert Saleh takes the preseason, so it’s not a surprise the Tennessee Titans won last week.

It’s also not surprising he’s confirmed his starters will go “about 20-25 plays” against the Seattle Seahawks, indicating they might even play the entire first half. 

Friday’s joint practice between the two teams saw the Titans give the Seahawks quite a fight, and Cam Ward looked very effective in the red zone portion of the practice. They also ran the ball with plenty of success. 

With the Seahawks likely to play their starters very little—if at all—I am not sure I see improvement over their first preseason game, when the Cowboys held them to just 156 yards of offense. 

Take the Titans and lay the points out to a -5.5 spread. 

 TOP PICK
Seahawks vs Titans Over/Under pick: Under 37.5 

Kalshi probability: 48%

It's that poor offensive output for the Seahawks that has me backing a low-scoring affair.

The Titans secondary registered a pick-6 off Sam Darnold in the joint practice and caused him issues throughout. Their pass rush also got home on Seattle's QB quite often.

Drew Lock didn't look terribly convincing against the Cowboys, throwing for just 40 yards on 13 passes. Now he's going to be short-handed a bit. WR Jake Bobo, who had five targets on Seattle's 20 throws, suffered a season-ending knee injury in Friday's scrimmage. 

While I see the Titans winning comfortably, I don't trust their backups to put up numbers. That will keep the scoring low enough for the Under to hit with room to spare.

Take this down to 35.5 points.

Seahawks vs Titans live odds

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Seahawks vs Titans weather

With temperatures in the upper 70s at kickoff and no rain, players should be in for a comfortable evening. 

How to watch Seahawks vs Titans

Location Nissan Stadium, Nashville, TN
Date Sunday, Aug. 23, 2026
Kickoff 8 p.m. ET
TV FOX

Seahawks vs Titans latest injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Jason Ence - Covers
Betting Analyst

Jason has been hooked on football since watching Real Madrid and Manchester United in the 2003 Champions League, and has been betting on the sport for nearly 15 years. He has given soccer gambling and fantasy advice for nearly a decade, writing for sites including Rotowire, SB Nation, and The TwinSpires Edge.

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