Monday Night Football Computer Picks: Our Best Week 12 Player Prop Projections

Our NFL player prop projections expect both passing attacks to find success tonight, highlighting our best Panthers vs. 49ers computer picks.

Jared Hochman - Content Operations Manager at Covers.com
Jared Hochman • Content Manager
Nov 24, 2025 • 09:04 ET • 4 min read
Panthers vs 49ers computer picks Bryce Young
Photo By - Imagn Images. Carolina Panthers quarterback Bryce Young (9) reacts to a touchdown.

Two NFC teams vying for a playoff spot clash on Monday Night Football tonight, with the Panthers visiting the 49ers to wrap up Week 12.

Our NFL player prop projections have identified the best MNF prop values for tonight, with a favorable outlook for both passing attacks.

Panthers vs 49ers computer picks for Monday Night Football

Panthers Panthers 49ers 49ers
Young o213.5 pass
-110
Purdy o255.5 pass
-110
Dowdle o18.5 rec
-110
McCaffrey o43.5 rec
-110
McMillan o63.5 rec
-120
Jennings o47.5 rec
-110
Sanders o17.5 rec
-110
Kittle o4.5 catches
-135
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Panthers MNF computer picks

Bryce Young Over 213.5 passing yards (-110)

Projection: 230.6 yards

Young is coming off a monstrous 448-yard performance, and while we don't project that type of outburst again, we do think he'll go Over his passing yardage total tonight.

Alternate-total bet
225+ yards (+135) - This prop is showing phenomenal value.

Rico Dowdle Over 18.5 receiving yards (-110)

Projection: 23.3 yards

The Carolina RB had 55 receiving yards last week and has multiple catches in five of his last seven games, so we're projecting him to be again involved in the pass game.

Tetairoa McMillan Over 63.5 receiving yards (-120)

Projection: 73.7 yards

We're projecting the star rookie to again finish above his receiving total, which would mark the fourth time in five games he's topped 60 yards.

Alternate-total bet
70+ yards (+105) - This price displays a good value.

Ja'Tavion Sanders Over 17.5 receiving yards (-110)

Projection: 21.7 yards

Sanders has topped this number in three of his last four games, and our projections put him Over tonight too.


More Monday Night Football picks from Covers


49ers MNF computer picks

Brock Purdy Over 255.5 passing yards (-110)

Projection: 262.9 yards

Purdy only threw for 200 yards in his return from injury last week, but we're projecting him to post a bigger number in what should be a more competitive game.

Christian McCaffrey Over 43.5 receiving yards (-110)

Projection: 47.2 yards

CMC averages 66.5 receiving yards per game and has topped 40 yards in every game — and we expect the dual-threat RB to be a major receiving threat again tonight.

Jauan Jennings Over 47.5 receiving yards (-110)

Projection: 59.3 yards

We're projecting the Niners WR to top this number for the third straight week against a suspect Carolina secondary.

Alternate-total bet
60+ yards (+160) - This prop shows decent value.

George Kittle Over 4.5 receptions (-135)

Projection: 4.5 receptions

Our projections put the star TE right at this line, but he does have 15 catches in his last two games and 4+ catches in four straight games.

Not intended for use in MA.
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Jared Hochman Content Operations Manager at Covers.com
Content Manager

Before Jared Hochman joined the Covers team in 2020, he worked for newspaper outlets such as the Chronicle Herald and The Coast, worked in marketing for SkipTheDishes and Vivid Seats, and previously ran a magazine. A journalism graduate from the University of King's College in, Halifax, N.S., "Hoch" brings more than a decade of experience in sports betting, having worked as a freelance handicapper, making appearances on Monumental Sports Network and the Sharp 600 podcast, and now also filling in occasionally as host of Covers' NHL Puck Props. 

Awarded Covers' company MVP for 2023, Jared is an avid bettor of MLB, NFL, NHL, and NBA, while also wagering on some soccer and WNBA. His best advice for sports bettors? Price shop, which is something he does daily across 10 different sportsbook apps.

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