Chiefs vs Seahawks Prediction, Picks & Odds for This Week’s NFL Preseason Game

Jones' prediction: Sam Darnold and more key contributors can get the Seahawks offense jumping early against the Chiefs.

Jeremy Jones - Contributor at Covers
Jeremy Jones • Betting Analyst
Aug 14, 2025 • 13:26 ET • 4 min read
Sam Darnold Seattle Seahawks NFL
Photo By - Imagn Images. Seattle Seahawks quarterback Sam Darnold (14) passes the ball.

Week 2 of preseason NFL football kicks off Friday night in Seattle, WA with the Kansas City Chiefs taking on the Seattle Seahawks.

We won’t see Patrick Mahomes and Travis Kelce, but we will see several other starters, including all the starters for the Seahawks.

Here are my top Chiefs vs. Seahawks predictions and NFL picks for Week 2 of the preseason on Friday, August 15.

Chiefs vs Seahawks prediction

Chiefs vs Seahawks Best bet: 1H Over 20.5 (+105)

In Week 1 of the preseason, the Kansas City Chiefs played all their starters, and the Seattle Seahawks sat most of them. Now we will get a reverse situation here in this Week 2 matchup.

It is unknown how long we will see Sam Darnold and the first team offense, but they will at least be out there for a series or two.

There is a very good chance that we see at least one score from these starters before they exit and turn things over to Drew Lock. However, last week, Lock and the second string still put up 16 points in the first half against the Las Vegas Raiders starters.

While the Chiefs did play all their starters last week, they only played one short series of 13 yards that was given to them off a fumble on the opening kickoff. They scored a touchdown and then moved on to Gardner Minshew, who will start this game.

Minshew played two drives that included a touchdown drive before turning things over to Bailey Zappe and then the scoring completely stopped.

I think we will see more than just two drives from Minshew and he and some of the other key contributors should be able to put up enough points to help hit this Over in the first half with the Seahawks starters on offense.

If you are looking for a bonus play, watch for a good second half Under in live betting. Especially if the second half is going to be Zappe and Chris Oladokun against Jalen Milroe. They may struggle to score double digits combined.

Chiefs vs Seahawks odds

  • Spread: Chiefs +3 (-110) | Seahawks -3 (-110)
  • Moneyline: Chiefs +140 | Seahawks -165
  • Over/Under: Over 39.5 (-110) | Under 39.5 (-110)

How to watch Chiefs vs Seahawks

Location: Lumen Field, Seattle, WA
Date: Friday, 8-15, 2025
Kickoff: 10:00 p.m. ET
TV: NFL Network

Chiefs vs Seahawks weather

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Jeremy Jones - Covers
Betting Analyst

Jeremy Jones was born and raised in Lexington, Kentucky and has been a massive Wildcats fans since the moment he came into the world. He wrote his first sports article at the tender age of 11 after attending a local AHL hockey game, and a few years later was writing professionally for sites such as Sports Rants, BetAmerica, and TwinSpires.

Jeremy holds a Masters in Sports Administration from Eastern Kentucky University and utilizes all seven betting options available in Kentucky to shop for odds and promos and find the greatest EV in every wager he places.

His best piece of sports betting advice is to stick to consistent unit sizes for every wager. He acknowledges there will occasionally be a bet that has a huge EV and you can play multiple units in one bet, but cautions against raising your unit size, because you can quickly lose all your winnings if you hit a minor cold streak.

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