NFL Week 12 has five games on the go before the weekend, including the standard three matchups on Thanksgiving Thursday.
Thought you would hit up your hometown bar and see the high school pals on Wednesday, November 25? Nope.
There’s a “Thanksgiving Eve” game on the go, with the Los Angeles Rams hosting the Green Bay Packers.
Planned on door-crashing the Best Buy for a killer deal on a new TV? You’d better be back in time to set it up for the standalone showdown on Black Friday.
With the 2026 NFL schedule release here, I’m getting a head start on planning my holiday viewing and making early NFL picks for the five games during Thanksgiving Week.
2026 Thanksgiving Week Schedule & Odds
For the first time ever, the NFL will play a game on “Thanksgiving Eve” with a standalone showcase on Wednesday, November 25.
Green Bay visits the L.A. Rams for an 8 p.m. ET primetime kickoff. That contest and the Black Friday game between the Denver Broncos and Pittsburgh Steelers bookend the usual three Thursday matchups.
Here's the schedule and look-ahead lines for those five contests.
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NFL Thanksgiving Schedule 2026
- Nov. 25, 8 p.m. ET:
Green Bay Packers at 
Los Angeles Rams - Nov. 26, 1 p.m. ET:
Chicago Bears at 
Detroit Lions - Nov. 26, 4:30 p.m. ET:
Philadelphia Eagles at 
Dallas Cowboys - Nov. 26, 8:20 p.m. ET:
Kansas City Chiefs at 
Buffalo Bills - Nov. 27, 3 p.m. ET:
Denver Broncos at 
Pittsburgh Steelers
NFL Thanksgiving Odds 2026
| Matchup | Spread | Moneyline | Over/Under |
|---|---|---|---|
 Packersvs  Rams |
+4.5 -120 -4.5 -102 |
+176 -210 |
o49.5 -115 u49.5 -105 |
|
|
+2.5 -115 -2.5 -105 |
+108 -126 |
o53.5 -112 u53.5 -108 |
|
|
+1.5 -118 -1.5 -104 |
-102 -116 |
o49.5 -115 u49.5 -105 |
|
|
+2.5 -106 -2.5 -114 |
+120 -142 |
o50.5 -105 u50.5 -115 |
|
|
-1.5 -110 +1.5 -110 |
-120 +102 |
o39.5 -110 u39.5 -110 |
Bears
Lions
Eagles
Cowboys
Chiefs
Broncos
SteelersPackers vs. Rams Early Prediction
Pick: Packers +4.5 (-120 at FanDuel)
Without knowing what’s going on in Week 11 for either side, I’m inclined to take the Green Bay Packers with the hook at +4.5.
Green Bay is expected to be one of the top contenders in the NFC, and while the Los Angeles Rams belong in that tier as well, the short week, combined with 11 games of wear and tear, could become an issue for veteran quarterback Matthew Stafford.
Bears vs. Lions Early Prediction
Pick: Under 53.5 (-108 at FanDuel)
The Detroit Lions have a new OC in Drew Petzing, who is focused on running the ball.
That's been the Chicago Bears' biggest soft spot on defense, so we could see the Lions grind out gains on the ground and keep Caleb Williams and the Bears offense on the sideline.
Both teams are disruptive on defense, with Chicago snatching INTs and Detroit bringing QB pressure.
Eagles vs. Cowboys Early Prediction
Pick: Cowboys -1.5 (-104 at FanDuel)
The Dallas Cowboys don’t have a great track record on Thanksgiving, going 4-11 ATS in their last 15 Turkey Day games. Dallas did, however, win and cover against Kansas City in last year’s annual holiday showcase.
Dak Prescott & Co. have also been dominant at home against NFC East opponents since 2021, going 13-2 SU and 12-3 ATS. I’ll lay the short number with America’s Team on Thanksgiving Day.
Chiefs vs Bills Early Prediction
Pick: Bills moneyline (-142 at FanDuel)
A lot could change for these teams between now and Thanksgiving (all eyes on Patrick Mahomes’ ACL recovery), but from what we know about this rivalry, we can predict a barnburner in Buffalo.
I’m going to pass on the point spread and simply take the Buffalo Bills to win outright. Six of the last 10 instalments in this rivalry have been decided by one score, with three of those coming by a field goal.
The brand new Highmark Stadium will be rocking with a well-oiled Bills Mafia, running on both Wild Turkey and actual turkey.
Broncos vs Steelers Early Prediction
Pick: Under 39.5 (-110 at FanDuel)
The Black Friday game is currently off the board as the Pittsburgh Steelers’ quarterback situation remains up in the air.
Maybe it’s Aaron Rodgers? Maybe it's Mason Rudolph?
The Denver Broncos also have concerns at quarterback, with Bo Nix coming off a broken ankle and two surgeries this offseason, though he’s expected to be ready for Week 1.
What we do know is that this matchup should feature a low total, fitting for those low, low prices on Black Friday.
