Anytime Touchdown Scorer Cowboys vs Lions Prediction: TD Picks for Thursday Night Football Week 14

A total of 54.5 indicates plenty of scoring, and our Cowboys vs. Lions anytime touchdown picks focus on a pair of young wide receivers.

Kyle LaRusic - Betting Analyst at Covers.com
Kyle LaRusic • Betting Analyst
Dec 3, 2025 • 14:22 ET • 4 min read
Dallas Cowboys wide receiver George Pickens (3) reacts after scoring a touchdown against the Las Vegas Raiders during the first half at Allegiant Stadium.
Photo By - Imagn Images. Dallas Cowboys wide receiver George Pickens (3) reacts after scoring a touchdown against the Las Vegas Raiders during the first half at Allegiant Stadium.

Finally, some competent offenses take the stage on Thursday Night Football when the Dallas Cowboys do battle with the Detroit Lions.

Both quarterbacks have a plethora of weapons at their disposal, and my Cowboys vs. Lions anytime touchdown picks single out one per side.

For more NFL picks, our full Cowboys vs. Lions predictions have you covered for Thursday, December 4.

Cowboys anytime touchdown pick

George Pickens (+120 at bet365)

Not one, not two, but three receivers caught touchdown passes for the Packers on Thanksgiving, and the Detroit Lions now have to deal with Dak Prescott & Co.

The Lions' secondary is once again depleted, and Prescott has two top receivers he can use to pick them apart. Both CeeDee Lamb and George Pickens have odds of +120 to find paydirt, but it's the latter who has my attention.

Pickens has been everything as advertised since coming to Dallas, and he's become one of Dak's favorite targets. The "WR2" is tied for the team lead with eight touchdowns and ranks first in both targets and catches.

That holds when the Cowboys reach the red zone, with Pickens catching seven of his team-high 15 RZ targets. Despite Lamb being the No. 1 option, Pickens always finds ways to be effective.

I expect Detroit to do its best to slow CeeDee down, leaving Pickens to do his thing. Both receivers may very well score, but at the same price, I see better upside riding with the former Steeler.

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Lions anytime touchdown pick

Isaac TeSlaa (+165 at bet365)

It's Isaac TeSlaa time, baby.

The third-round pick out of Arkansas caught two catches for 35 yards and a touchdown last week, picking up more snaps following Amon-Ra St. Brown's injury.

With Dan Campbell's psychotic mind having a whole week to integrate him into more plays, TeSlaa could see a huge boost. 

The 23-year-old has just six receptions on the season, but three of those came in the end zone. He's a trusted target when the Lions get in deep, and he can also beat you downfield. That's music to Jared Goff's ears, especially inside a dome.

Before last week, his highest snap percentage came in Week 6 against the Chiefs when he played in 46%. Last week's 92% snap percentage was a clear indication that Campbell trusts TeSlaa to be a big part of this offense moving forward — especially with key players like St. Brown and Sam LaPorta MIA.

And sometimes, opportunity is all you need. At +165, I'll happily take a stab at the rook finding paydirt vs. a Cowboys defense near the bottom of the league in almost every category.

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Kyle LaRusic - Covers
Betting Analyst

Kyle LaRusic joined Covers in 2020 with a Holland College diploma in Journalism and a Mount Saint Vincent Degree in Public Relations. Stints at Amherst News and the Cape Breton Post helped sharpen his skills in a newsroom setting, while working for MSVU and Dalhousie’s athletic departments landed Kyle in his comfort zone.

Kyle has been an avid bettor for over five years, starting with just one Sports Interaction account before discovering both the beauty and importance of price shopping. bet365 and Pinnacle are his go to books, but accounts at 10+ sportsbooks give him an array of options. “Rusty” will bet on anything under the sun as long as there’s value and good reasoning behind it, but NHL and NFL are his two favorite leagues to watch and wager on — especially with friends.

Kyle’s biggest tip for any bettor is simple: gamble responsibly. Only bet what you’re willing to lose and make sure to install a proper bankroll method to keep track of your ROI. If you’re still dwelling on the amount you lost the next day, it’s time to decrease your spending.

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