College Football Picks Against the Spread for Week 12

Our Week 12 ATS college football picks are taking the points with Texas against Georgia and backing Alabama against Oklahoma at home.

Chris Gregory - Betting Analyst at Covers.com
Chris Gregory • Betting Analyst
Nov 11, 2025 • 13:52 ET • 4 min read
Arch Manning Texas Longhorns SEC college football
Photo By - Imagn Images. Arch Manning drops back to pass against Kentucky.

Week 12 in college football is headlined by two massive battles in the SEC: Oklahoma at Alabama and Texas at Georgia. With the regular season winding down, the stakes couldn't be higher.

I pick a side for those big games and more in my Week 12 ATS college football picks below.

College football picks against the spread for Week 12

Matchup Pick
Notre Dame Notre Dame vs Pittsburgh Pittsburgh Pittsburgh (+11.5)
South Carolina South Carolina vs Texas A&M Texas A&M Texas A&M (-18.5)
Wisconsin Wisconsin vs Indiana Indiana Indiana (-29.5)
Iowa Iowa vs USC USC USC (-6.5)
Oklahoma Oklahoma vs Alabama Alabama Alabama (-5.5)
Utah Utah vs Baylor Baylor Utah (-8.5)
Texas Texas vs Georgia Georgia Texas (+6.5)
TCU TCU vs BYU BYU BYU (-4.5)

Lines courtesy of FanDuel as of 11-11.

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Expert Week 12 CFB ATS picks

Notre Dame (-11.5) vs Pittsburgh: Pittsburgh Pittsburgh +11.5 

Pittsburgh is far from perfect, but has an offense that can score with the best of them. This could be a tricky spot for Notre Dame.

South Carolina vs Texas A&M (-18.5): Texas A&M Texas A&M -18.5

Texas A&M has avoided the obvious slip-ups of years past and has looked the part of a true national title contender. Aggies roll at home.

Wisconsin vs Indiana (-29.5): Indiana Indiana -29.5

Don't be fooled by Wisconsin's upset win over Washington; its leading passer was its punter. Indiana will dominate from start to finish.

Iowa vs USC (-6.5): USC USC -6.5

I worry about Iowa emptying the tank against Oregon last week, and USC has been dominant at home this season (4-1 ATS, 49.2 points per game)

Oklahoma vs Alabama (-5.5): Alabama Alabama -5.5

Oklahoma taking down Tennessee two weeks ago masks the fact that they got outgained by 105 yards. Joey Aguilar threw for 393 yards and three scores in that game, and I suspect Ty Simpson will do something similar.

Utah (-8.5) vs Baylor: Utah Utah -8.5

Utah has looked dominant since losing to BYU three weeks ago, but has work to do to book a spot in the Big 12 title game. The Utes won't take this lightly.

Texas vs Georgia (-6.5): Texas +6.5

Georgia seems to be peaking at the right time, but Texas is also playing its best ball. Give me the points in one of the more important games of the year.

TCU vs BYU: BYU BYU -4.5

You almost throw out what BYU's offense did against Texas Tech but Texas Tech's defense is simply that good. This is a good spot to get back on track


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Chris Gregory Covers.com
Betting Analyst

In his four years on the Covers editorial team, Chris Gregory has helped bolster the site’s golf and college football coverage. He brings a journalism and marketing background to his work as a Publishing Editor and can be found across our site covering the Masters, college football futures, and more.

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