Texas vs Duke Prediction, Picks & Odds for Tonight's College Basketball Game

Ponnaiya's prediction: Duke rolls Texas.

Rohit Ponnaiya - Betting Analyst at Covers.com
Rohit Ponnaiya • Betting Analyst
Nov 4, 2025 • 13:34 ET • 4 min read

NCAAB

Match starts: 2 hrs
DUKE
53 %
TEX
47 %
EXPERT PICK - SPREAD
Duke -9.5 (-110) Duke -9.5 (-110)
Read Analysis
Duke forward Cameron Boozer (12) and guard/forward Nikolas Khamenia (14).
Photo By - Imagn Images. Duke forward Cameron Boozer (12) and guard/forward Nikolas Khamenia (14).

The Duke Blue Devils open their 2025-26 season with a clash against the Texas Longhorns at the Dick Vitale Invitational on Tuesday night.

The Blue Devils are the No. 6-ranked team in the country and with freshman Cameron Boozer leading the charge, my Texas vs. Duke predictions expect them to roll the unranked Longhorns.

Here are my best free college basketball picks for this marquee matchup on November 4.

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Texas vs Duke prediction

Texas vs Duke best bet: Duke -9.5 (-110)

The Duke Blue Devils lost their biggest names from last year's Final Four team, with Cooper Flagg, Kon Kneuppel, and Khaman Maluach all in the NBA.

That said, there are several returning rotation players who should thrive in bigger roles. That includes guard Caleb Foster, defensive stopper Maliq Brown, center Patrick Ngongba II, and sophomore Isaiah Evans, who had some big scoring games despite limited minutes. 

Add them to the No. 1 recruiting class in the country, led by No. 1-ranked power forward Cameron Boozer and No. 4 point guard Cayden Boozer, and this school will be a title contender again. This is a talented squad that has depth, length, athleticism, positional versatility, and shooting. 

I'm a lot less optimistic about the unranked Texas Longhorns, who went just 8-15 against high-major opponents last season while losing in the First Four.

Texas said goodbye to its top two scorers (including star SG Tre Johnson) as well as starting center Kadin Shedrick. Transfer Dailyn Swain will shoulder a big load, but the other transfers won't do much, and I don't see any of the incoming freshmen making an impact early. 

Texas had a recent closed-door scrimmage against TCU that it lost 91-72. Meanwhile, Duke was able to build on-court chemistry in exhibition wins against UCF (96-71) and No. 17 Tennessee (83-76) in front of a sold-out crowd in Knoxville. 

While this contest is at a neutral site, the fans in Charlotte should provide a home-court atmosphere for Duke. Back the Blue Devils to roll to a double-digit win tonight.

Texas vs Duke same-game parlay

The 2025 college basketball recruiting class was viewed as having three elite players: Darryn Peterson, AJ Dybantsa, and Cameron Boozer. Peterson and Dybantsa scored more than 20 points in their college debuts last night, and I expect the same from Boozer. 

The 6-9, 250-pound power forward averaged 28.5 ppg and 17.5 rpg in two exhibition games. He'll torch a banged-up Texas frontcourt that is likely missing bigs Lassina Traore and Matas Vokietaitis.

Texas vs Duke SGP

  • Duke -9.5
  • Cameron Boozer Over 20.5 points
  • Cameron Boozer Over 10.5 rebounds

Our beyond the arc SGP: Duke's Cameron goes crazy

Since I'm expecting Duke to cover a sizable spread and backing Boozer to eclipse his points total, it also makes sense to take the full game Over.

New head coach Sean Miller should get Texas playing at a faster pace than previous years, and Duke's best defensive player, Maliq Brown, might not be ready to return to the lineup after minor knee surgery. 

Texas vs Duke SGP

  • Duke -9.5 
  • Cameron Boozer Over 20.5 points
  • Cameron Boozer Over 10.5 rebounds
  • Over 153

Texas vs Duke odds

  • Spread: Texas +9.5 | Duke -9.5
  • Moneyline: Texas +350 | Duke -450
  • Over/Under: Over 153 | Under 153

Texas vs Duke betting trend to know

The Blue Devils have covered the first half spread in 20 of their last 26 games (+13.10 Units / 44% ROI. Find more NCAAB betting trends for Texas vs. Duke.

How to watch Texas vs Duke

Location Spectrum Center, Charlotte, NC
Date Tuesday, November 4, 2025
Tip-off 8:45 p.m. ET
TV ESPN

Texas vs Duke key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Rohit Ponnaiya
Betting Analyst

With a background playing soccer, rugby, and boxing, combined with a journalism degree, it's little surprise that Rohit gravitated towards the world of sports betting. He specializes in betting on UFC and college basketball, two sports where the eyeball test can tell you a lot more about matchups than analytics. Rohit has years of experience handicapping NFL and NBA games as well as niche betting markets such as politics. He's also the resident CFL expert and formerly hosted "The Chez and Ro Show" with former CFL star Davis Sanchez.

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