There’s a new No. 1 team in the country as the Duke Blue Devils travel to South Bend tonight to take on the Notre Dame Fighting Irish.
Notre Dame sits at just 3-11 in ACC play, but my Duke vs. Notre Dame predictions are backing the Irish to keep this one closer than expected.
Here are my best free college basketball picks for this conference clash on Tuesday, February 24.
Duke vs Notre Dame prediction
Duke vs Notre Dame best bet: Notre Dame +17.5 (-110)
The Duke Blue Devils are coming off a statement win over then-No. 1 Michigan and have a showdown with No. 11 Virginia looming on Saturday. That makes this road trip to face the struggling Notre Dame Fighting Irish feel like a classic letdown spot.
Notre Dame has quietly covered spreads against quality competition, cashing tickets in recent games versus Virginia, Louisville, and SMU — all Top-30 teams in the NET rankings.
The Irish also play at a snail’s pace, limiting possessions and making it tougher for Duke to create separation. Add in their size and a defensive rebounding rate that ranks 23rd nationally, and Notre Dame has the profile to limit second-chance opportunities and keep this one within reach.
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Duke vs Notre Dame same-game parlay
The Irish lost leading scorer Markus Burton to a season-ending injury in December, and while Jalen Haralson has stepped up offensively, he’s expected to miss his third straight game with an ankle sprain.
Without their top two scoring options against Duke’s elite defense, Notre Dame will struggle to generate consistent offense, setting the stage for a slower, lower-scoring contest.
Wooden Award favorite Cameron Boozer averages 10.0 rebounds per game, but he may see reduced minutes if Duke builds a comfortable lead early. Pair that with the projected sluggish tempo, and the overall rebounding opportunities could be limited.
Duke vs Notre Dame SGP
- Notre Dame +17.5
- Under 140
- Cameron Boozer Under 9.5 rebounds
Our beyond the arc SGP: Coach's Son
Someone will have to shoulder the scoring load for Notre Dame, and that role will likely fall to Braeden Shrewsberry, son of head coach Micah Shrewsberry.
Shrewsberry has scored 16 or more points in six of his last eight games and grabbed at least three rebounds in 10 of his last 15 contests.
Duke vs Notre Dame SGP
- Notre Dame +17.5
- Under 140
- Braeden Shrewsberry Over 11.5 points
- Braeden Shrewsberry Over 3.5 rebounds
Duke vs Notre Dame odds
- Spread: Duke -17.5 (-110) | Notre Dame +17.5 (-110)
- Moneyline: Duke -2000 | Notre Dame +1000
- Over/Under: Over 140 (-110) | Under 140 (-110)
Duke vs Notre Dame betting trend to know
The Blue Devils have gone 19-8 to the Under this season. Find more college basketball betting trends for Duke vs. Notre Dame.
How to watch Duke vs Notre Dame
| Location | Purcell Pavilion, South Bend, IN |
| Date | Tuesday, February 24, 2026 |
| Tip-off | 7:00 p.m. ET |
| TV | ESPN |
Duke vs Notre Dame key injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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