With Victor Wembanyama expected back for Game 4, my Spurs vs. Trail Blazers predictions expect San Antonio to deliver another win on the road and cover a modest spread.
Here are my best free NBA picks for Game 4 on Sunday, April 26, from Moda Center.
Spurs vs Trail Blazers prediction
Spurs vs Trail Blazers best bet: Spurs -5.5 (-110)
The San Antonio Spurs and Portland Trail Blazers have faced off six times this season, including the playoffs, and San Antonio is 4-2 ATS in those contests.
San Antonio is 24-17-1 ATS on the road and 14-12-1 ATS as the road favorite. The visiting team covered the spread in 25 of 45 games when favored by at least 5.5 points, including a 10-7 mark when favored by that many on the road.
The Spurs were one of the best two-way teams in the Association this season. San Antonio boasted the second-best net rating (8.4), the third-best offensive rating (118.7), and the third-best defensive rating (110.4).
On the road, the Spurs were even better defensively, with a 109.4 defensive rating, the second-best mark in the league. San Antonio’s 8.4 net rating on the road ranked second in the Association.
Conversely, the Blazers have struggled on both ends of the floor this season. Portland ranks 21st in offensive rating (113.1), 11th in defensive rating (113.5), and 19th in net rating (-0.4).
At Moda Center, Portland has been even worse, ranking 23rd in offensive rating (110.6) and 17th in net rating (-3.2).
Portland was comfortably defeated in Games 1 and 3, and it took a mid-game injury to Victor Wembanyama and a career scoring night from Scoot Henderson to come away with a three-point win in Game 2.
Wemby’s return should fuel the Spurs to victory, as they look ahead to Game 5 and a gentleman’s sweep at home.
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Spurs vs Trail Blazers same-game parlay
Five of six head-to-head matchups between the Spurs and Blazers have gone Under, and at 219 points, I expect that trend to continue in Game 4. With Defensive Player of the Year Victor Wembanyama back in action, the Spurs can lock down Portland’s offense and keep this matchup low-scoring.
Wembanyama delivered 35 points in Game 1 before getting concussed in Game 2 and missing most of the contest. Including that shortened stint on the court, Wemby has averaged 29.7 points over his last 18 games, scoring 28+ 10 times. He’s cashed the Over on this scoring line in five of his last six healthy games.
Spurs vs Trail Blazers SGP
- Spurs -5.5
- Under 219
- Victor Wembanyama Over 27.5 points
Our "from downtown" SGP: Spurs Roll!
Reigning Rookie of the Year Stephon Castle and 2026 first-round pick Dylan Harper led the Wembanyama-less Spurs to victory in Game 3, and I expect them to stay productive in Game 4.
Stephon Castle finished with a 33/2/5 line in Game 3 after posting 30 and 31 in Games 1 and 2. Castle has averaged 34.2 PRA across his last 12 games while cashing the Over on this line eight times.
Dylan Harper finished his rookie season with averages of 19.1 PRA, going for at least 17 in 44 of 69 total appearances. He reached that mark in 24 of 38 road games, and he posted a monster 27/10/3 line in Game 3.
Spurs vs Trail Blazers SGP
- Spurs -5.5
- Victor Wembanyama Over 27.5 points
- Stephon Castle Over 30.5 points+rebounds+assists
- Dylan Harper Over 16.5 points+rebounds+assists
Spurs vs Trail Blazers odds for Game 4
- Spread: Spurs -5.5 | Trail Blazers +5.5
- Moneyline: Spurs -220 | Trail Blazers +180
- Over/Under: Over 219 | Under 219
Spurs vs Trail Blazers betting trend to know
The San Antonio Spurs have covered the 1H Spread in 28 of their last 35 away games (+20.05 Units / 49% ROI). Find more NBA betting trends for Spurs vs. Trail Blazers.
How to watch Spurs vs Trail Blazers Game 4
| Location | Moda Center, Portland, OR |
| Date | Sunday, April 26, 2026 |
| Tip-off | 3:30 p.m. ET |
| TV | ESPN |
Spurs vs Trail Blazers latest injuries
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