The Philadelphia 76ers look to end a three-game losing skid when they visit Gainbridge Fieldhouse and the Indiana Pacers.
Indiana competes every night, and my 76ers vs. Pacers predictions expect the Pacers to cover again as massive underdogs.
Read on for my NBA picks for Friday, April 10.
76ers vs Pacers prediction
76ers vs Pacers best bet: Pacers +15 (-110)
Tonight's game isn't about whether the Philadelphia 76ers will beat the Indiana Pacers or not, because they probably will.
This game is about whether Philadelphia can sustain the kind of dominant, wire-to-wire performance required to win by at least 16 points against a team that has quietly been one of the most reliable covers in the league.
The Pacers are 8-2 against the spread in their last 10 games. That number doesn’t lie. It doesn’t care about the moneyline or that Indiana is usually a massive underdog.
Indiana is playing at one of the fastest paces in the league, and they’re shooting an efficient 59.8 eFG% over that 10-game stretch.
The Pacers aren’t a team surviving on effort alone. The Pacers can score, and they do it efficiently. Philadelphia is allowing 118.7 points per game, and Indiana is giving up 121.9, so stops are going to be hard to find.
That sets the tone for the entire matchup: fast pace, quick shots, and constant scoring runs.
In games like that, big spreads become fragile. You’re not just asking the 76ers to win, you’re asking them to maintain focus, energy, and execution for 48 minutes.
That’s a much bigger ask than it looks. Take the points and the Pacers to cover this massive line.

76ers vs Pacers same-game parlay
Three angles, one direction. Indiana covers because neither defense can stop anyone right now.
That same offensive freedom is exactly why VJ Edgecombe gets his points in a track-meet pace game, and he’s scored at least 17 points in three of his previous five.
And when both teams are bleeding 119 plus points per game with the pace we’ll see tonight, we’ll take a stab at the Over.
76ers vs Pacers SGP
- Pacers +15
- V.J. Edgecombe Over 16.5 points
- Over 233.5
Our "from downtown" SGP: Tons of triples
Jay Huff didn’t attempt a 3-point shot in the Pacers' victory over Brooklyn, but he’s made at least two triples in three of his past five games.
Kelly Oubre has been letting it fly, and he’s made at least two long-range bombs in three of his previous five games.
Paul George is coming off a 0-for-5 3-point stinker but has made at least three triples in seven of his previous eight games.
Tyrese Maxey averages three made threes per night. He went 5-for-10 last night from downtown, snapping a five-game skid where he failed to make three triples or more.
76ers vs Pacers SGP
- Jay Huff Over 1.5 made threes
- Kelly Oubre Over 1.5 made threes
- Paul George Over 2.5 made threes
- Tyrese Maxey Over 2.5 made threes
76ers vs Pacers odds
- Spread: Philadelphia -15.5 | Indiana +15.5
- Moneyline: Philadelphia -1300 | Indiana +800
- Over/Under: Over 234.5 | Under 234.5
76ers vs Pacers betting trend to know
The Pacers are 8-2 ATS in their last 10 games. Find more NBA betting trends for 76ers vs. Pacers.
How to watch 76ers vs Pacers
| Location | Gainbridge Fieldhouse, Indianapolis, IN |
| Date | Friday, April 10, 2026 |
| Tip-off | 7:30 p.m. ET |
| TV | NBC Sports Philadelphia, FDSN Indiana |
76ers vs Pacers latest injuries
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