The latest edition of the Hudson River Derby on Friday night kicks off a jam-packed weekend of MLS action.
Our MLS preview for Matchday 27 dives into an entertaining match between New England and Orlando for important playoff points, while rivalries take the stage in Dallas and San Jose.
Here are our MLS moneyline picks for Matchday 27!
MLS moneyline picks for Matchday 27
For help understanding Kalshi probabilities, please see our odds calculator.
| Game | Pick |
|---|---|
 New York Red Bulls vs  New York City FC |
Draw 24% |
 D.C. United vs  Charlotte FC |
Charlotte 42% |
 New England Revolution vs  Orlando City SC |
New England 50% |
 CF Montreal vs  Columbus Crew SC |
Draw 26% |
 San Jose Earthquakes vs  LAFC |
Draw 24% |
 FC Dallas vs  Austin FC |
Dallas 57% |
 Houston Dynamo vs  FC Cincinnati |
Houston 51% |
 Sporting Kansas City vs  Philadelphia Union |
Philadelphia Union 59% |
 Minnesota United FC vs  LA Galaxy |
Draw 21% |
 St. Louis CITY SC vs  Toronto FC |
St. Louis 60% |
 Colorado Rapids vs  Seattle Sounders FC |
Colorado 52% |
 Nashville SC vs  Chicago Fire |
Nashville 54% |
 Real Salt Lake vs  Vancouver Whitecaps FC |
Vancouver 53% |
 Portland Timbers vs  Atlanta United FC |
Portland 46% |
 Inter Miami FC vs  San Diego FC |
Inter Miami 68% |
Percentages courtesy of Kalshi, one of the best prediction market apps
Start trading with Kalshi today!
Sign up now using our Kalshi promo code 'COVERS60' and trade $25 on any event contracts to get $60 — including MLS!
*Eligible U.S. locations only
Expert MLS moneyline picks for Matchday 27
New York Red Bulls vs New York City FC pick: Draw
NYCFC have owned the Hudson River Derby of late, winning five of the last seven. That said, neither club is performing well at the moment and NYCFC has taken just 16 points from 13 home matches. They'll share the spoils for the second time in the league this season.
DC United vs Charlotte FC pick: Charlotte
DC United come in unbeaten in their last three, but they've also managed just to score three goals in their last five outings. Charlotte has 10 goals in that same span, and offer value as a road favorite below 45% probability.
New England Revolution vs Orlando City pick: New England
There is value on New England in this spot. Orlando's five-match unbeaten run came to an end in Columbus on Wednesday in the US Open Cup, and they fielded a fairly strong side. The Revs return home after wins at Chicago and NYCFC, and only Nashville has claimed more points per match at home in the East.
CF Montreal vs Columbus Crew SC pick: Draw
Both Montreal and the Crew played mid-week and wonm with Montreal defeating Montreal in the Canadian Championship semi-finals. Fatigue is likely to be a factor, and neither club has shown consistent form. This is a great price for the draw.
San Jose Earthquakes vs LAFC pick: Draw
These sides don't like each other, and LAFC will want revenge for their 4-1 home defeat to San Jose in April. That San Jose side is long gone though, although their recent four-match unbeaten run has fans hopeful. LAFC have just one victory in their last eight in all comps, and the 3-1 shocking loss to Sporting KC has me leery to take them to win. The draw is the way to go.
FC Dallas vs Austin FC pick: Dallas
Austin have put together a decent run, with a shocking win in Vancouver giving them eight of a possible 12 points. But Dallas have taken 10 of 12, are 4-1-0 in their last five with Austin, and will have the advantage of Austin CB Guilherme Biro missing out due to suspension.
Houston Dynamo vs FC Cincinnati pick: Houston
Both clubs come in with just one win and two defeats in their last five matches, having faced some difficult sides in the process. But Houston does something Cincinnati does not—defend. FCC has conceded 12 goals in their last three matches, while Houston has allowed just two. That's why they'll get the victory.
Sporting Kansas City vs Philadelphia Union pick: Philadelphia Union
There isn't a hotter team in MLS right now than the Union, and Cavan Sullivan is tearing the league apart. Sporting pulled off a surprising win over LAFC last week, but their defense will have no answer for a Philly side with 15 goals scored in their last four matches.
Minnesota United FC vs LA Galaxy pick: Draw
The suspension to Minnesota RWB Kyle Duncan is a significant one for a side that struggles to generate chances. It also puts the replacement in a tough spot dealing with Chuckie Lozano, who is starting to link up with with Marco Reus. That said, the Galaxy have won just three of their last 30 away fixtures in MLS. This one will end level.
St. Louis CITY SC vs Toronto FC pick: St. Louis
The St. Louis steamroller can't be stopped, as their US Open Cup semi-final win on Wednesday saw them push their unbeaten streak to 17 matches in all competitions. Toronto must deal with the loss of Nelson Palacio for the season after just one match with the club, and do so away from home—where they've taken just nine of a possible 33 points.
Colorado Rapids vs Seattle Sounders pick: Colorado
The Rapids have dropped just nine points in 12 home matches this season, and have yet to share the spoils. The Sounders have done nothing but draw of late, with their last four fixtures ending all square. Their injury list continues to be a burden, and the only clubs to win in Colorado this season are St. Louis (twice) and Dallas. The Sounders aren't going to join that group, nor will they get a point.
Nashville SC vs Chicago Fire pick: Nashville
The Fire have been anything but of late, with their loss to New England last weekend seeing them woefully underperform their xG. Nashville's recent skid has come away from home, but they've won nine straight MLS fixtures at home and are unbeaten in 11 league outings at GEODIS Park. They'll get back to winning ways with a week's rest.
Real Salt Lake vs Vancouver Whitecaps pick: Vancouver
Vancouver was left stunned last week by Austin, and then fell midweek in the Canadian Championship to Montreal. But any hopes Real Salt Lake had of springing an upset went to the wayside with Thursday's news that Diego Luna's season is over due to a knee injury. The Whitecaps will get back on track against a reeling RSL side without its leader.
Portland Timbers vs Atlanta United pick: Portland
The addition of Breel Embolo has not solved Atlanta United's inability to get wins, as a 0-0 draw with DC United left them with two points from a possible 12 and all but eliminated from playoff contention. The Timbers are holding onto a playoff spot out West, and are 4-0-2 at home in league play since the World Cup break. They'll keep pace with the other playoff contenders and get all three points.
Inter Miami FC vs San Diego FC pick: Inter Miami
New Inter Miami maanger Kily Gonzalez will make his MLS managerial debut off the back of Wednesday's Campeones Cup victory over Cruz Azul, which saw their unbeaten run pushed to five matches. San Diego's cross-country trip will see them lose for the fourth match on the trot, although perhaps not as poorly as their 5-0 thrashing last weekend at the hands of Philly.
That said, as long as the probability on this one is north of 64%, it is a NON-PLAY.
- Moneyline picks: 125-177, -6.0 units
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.
