The Minnesota Twins are in a great position to take down the Houston Astros tonight with Joe Ryan on the hill.
Behind the righty's recent dominance, my Twins vs Astros predictions target a win for the visitors.
Read more in my MLB picks for Tuesday, June 30.
Who will win Twins vs Astros today: Twins (-112)
The Minnesota Twins hand Joe Ryan the baseball this evening. He's in great form, posting a 2.19 FIP over his last two appearances while allowing just 0.82 HR/9. Ryan has also compiled a respectable 3.82 FIP over the last month.
As for Houston Astros starter Mike Burrows, he has an alarming 6.65 FIP across his last five outings while allowing a 42.7% hard hit rate during that span.
Burrows comes up against a Twins offense swinging it well right now. They have a .262 average as a team across the last seven days and 106 wRC+.
Minnesota will add to Burrows' struggles, and Ryan will contain Houston.
I'll play this pick to -130.
COVERS INTEL: The Astros have a 32.8% hard hit rate across their last seven games, compared to a 37.4% mark overall this season. They're not consistently squaring up the baseball. 
Twins vs Astros Over/Under pick: Over 8.5 (+101)
While I do expect Ryan to bring his best tonight, the Twins' bullpen is a slight concern when he exits.
They own a 6.01 xERA across the last week while allowing 2.91 HR/9. Houston's offense has a .185 ISO over its last seven contests, and has the power to capitalize if Minnesota's relievers continue making mistakes.
Houston's bullpen has been much steadier with a 3.94 xERA over the last week, but I expect Minnesota's hot offense to do most of its damage against Burrows before the relievers enter. That should be enough to help push this game Over the total.
A 5-4, 6-4 scoreline is possible.
I'll play this pick to -120.
- ML/RL bets: 32-28, +1.62 units
- Over/Under bets: 33-26, +2.39 units
Twins vs Astros weather
Twins vs Astros odds
- Moneyline: Twins -108 | Astros +104
- Run line: Twins -1.5 (+156) | Astros +1.5 (-163)
- Over/Under: Over 8.5 (+104) | Under 8.5 (-108)
Twins vs Astros trend
The Twins have hit the game total Over in 22 of their last 35 games (+10.00 Units / 26% ROI). Find more MLB betting trends for Twins vs. Astros.
How to watch Twins vs Astros and game info
| Location | Daikin Park, Houston, TX |
| Date | Tuesday, June 30, 2026 |
| First pitch | 8:10 p.m. ET |
| TV | Twins.TV, SCHN |
| Twins starting pitcher | Joe Ryan (5-4, 3.18 ERA) |
| Astros starting pitcher | Mike Burrows (3-8, 5.48 ERA) |
Twins vs Astros latest injuries
Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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