Red Sox vs Tigers Prediction, Picks & Odds for Today's MLB Game

Ed Scimia - Contributor at Covers.com
Ed Scimia • Betting Analyst 17+ years betting experience
Updated: May 6, 2026 , 01:01 PM ET • 4 min read

Jack Flaherty is grinding, and it's not going well. He won't right the ship today, either, and the Red Sox will tee off on the right-hander.

MLB

May 06 • 6:40 PM ET
BOS
48 %
DET
52 %
EXPERT PICK - MONEYLINE
Boston +102 Boston +102
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Wilyer Abreu Jarren Duran Ceddanne Rafaela Boston Red Sox MLB
Photo By - Reuters Connect. Boston Red Sox outfielders Wilyer Abreu (52), Jarren Duran (16) and Ceddanne Rafaela (3) celebrate their win over the Detroit Tigers

The Boston Red Sox will look to complete a three-game sweep as they wrap up their road series against the Detroit Tigers tonight.

Detroit will send the wild Jack Flaherty to the mound, which is why I’m taking Boston to win in my Red Sox vs. Tigers predictions.

Read on to learn more and get my free MLB picks for Wednesday, May 6. 

Who will win Red Sox vs Tigers today: Red Sox moneyline (+102)

Detroit Tigers starter Jack Flaherty (0-2, 5.90 ERA) is suffering through the worst stretch of his career. Flaherty leads the AL in walks, allowing 7.8 free passes per nine innings, which has ballooned his WHIP to 1.793 over his first seven starts.

Flaherty hasn’t made it out of the fourth inning in any of his last three starts. That includes an April 20 appearance against the Boston Red Sox in which he walked six batters in 3.1 innings of work.

Boston teed off against Framber Valdez yesterday and should produce more than enough offense again tonight to finish off a series sweep.

Covers COVERS INTEL: Flaherty has produced a chase rate of just 21.2% this season, placing him in the third percentile among pitchers while walking 17.7% of batters he’s faced.

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Red Sox vs Tigers Over/Under pick: Over 8.5 (-105)

I don’t see the Red Sox needing much help to hit the Over tonight, but the Tigers should put up a few runs to help against Sonny Gray. The Boston starter is coming off the IL after suffering a hamstring strain in his last start against Detroit. 

The Tigers have been league-average in terms of scoring but far more effective against righties, hitting to a .743 OPS against right-handed pitching this year.

Detroit’s .344 xwOBA is the fourth best in the league, suggesting it's better than its results have shown. That’s enough firepower to bring the total to the Over.

Ed Scimia's 2026 Transparency Record
  • ML/RL bets: 5-11, -6.31 units
  • Over/Under bets: 5-9, -4.43 units

Red Sox vs Tigers odds

  • Moneyline: Red Sox -108 | Tigers -112
  • Run line: Red Sox -1.5 (+144) | Tigers +1.5 (-175)
  • Over/Under: Over 8.5 (-112) | Under 8.5 (-112)

Red Sox vs Tigers trend

The Red Sox and Tigers have combined to hit the Over in four straight meetings. Find more MLB betting trends for Red Sox vs. Tigers.

How to watch Red Sox vs Tigers and game info

Location Comerica Park, Detroit, MI
Date Wednesday, May 6, 2026
First pitch 6:40 p.m. ET
TV NESN, DSN
Red Sox starting pitcher Sonny Gray
(2-1, 4.30 ERA)
Tigers starting pitcher Jack Flaherty
(0-2, 5.90 ERA)

Red Sox vs Tigers latest injuries

Red Sox vs Tigers weather

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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Ed Scimia - Covers.com
Betting Analyst

Ed Scimia has been writing about the gaming industry for over 15 years. He graduated from Syracuse University with degrees in Magazine Journalism and Political Science in 2003, and has covered major gambling events like the World Series of Poker in his career. Since joining Covers in 2022, Ed has offered his sports betting analysis primarily on MLB, NFL, college football, and college basketball games, but is willing to take on any sport.

His betting strategy focuses more on finding line value based on deviations from the market rather than traditional handicapping, primarily shopping between DraftKings, FanDuel, and Fanatics in his home state of Connecticut, though he’s not afraid to do deep game analysis to find profitable bets at any book.

Outside of gambling, Ed is an avid curler who competes in mixed doubles on the World Curling Tour and runs a popular curling YouTube channel, Chess on Ice. That experience has come in handy during the Olympics, when he has proven to be a successful curling bettor as well. 

Ed's advice to new bettors is to always open multiple sportsbook accounts and check the odds at each before placing any bet. Successful sports betting is about consistently beating the closing line value, which requires finding spots where one book is offering odds far better than the rest of the market and jumping on those opportunities.

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